• Title, Summary, Keyword: Herbal medicine

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Anti-inflammatory Effects of Sam-chul-kun-bi-tang

  • Lee, Jin-Ah;Ha, Hye-Kyung;Jung, Da-Young;Lee, Ho-Young;Lee, Nam-Hun;Lee, Jun-Kyoung;Huang, Dae-Sun;Shin, Hyeun-Kyoo
    • The Journal of Korean Medicine
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    • v.31 no.3
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    • pp.47-54
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    • 2010
  • Objective: To derive information on the efficacy of Sam-chul-kun-bi-tang (SKT), by evaluating its anti-inflammatory effect. SKT is a widely-used herbal formula in traditional Korean medicine. In man y studies, plant-derived anti-inflammatory efficacies have been investigated for their potential inhibitory effects on lipopolysaccharide (LPS)-stimulated macrophages. This study was performed to examine the anti-inflammatory effects of SKT extract on LPS-stimulated RAW 264.7 cells. Methods: The production of nitric oxide (NO), prostaglandin $(PG)E_2$, tumor necrosis factor (TNF)-$\alpha$ and interleukin (IL)-6 were examined in a macrophage cell line, RAW 264.7 cells, in the presence of SKT. RAW 264.7 cells were incubated with LPS 1 ${\mu}g/mL$ and SKT for 18 hrs. The anti-inflammatory activity of SKT was investigated by carrageenan-induced paw edema in rats. The paw volume was measured at 2 and 4 hrs following carrageenan-induced paw edema in rats. Results: SKT showed inhibitory effect on $PGE_2$, TNF-$\alpha$ and IL-6 in LPS-stimulated RAW 264.7 cells. But SKT was not inhibitory effect on NO by LPS-stimulated RAW 264.7 cells. Administration of SKT (1 g/kg) also showed a reduction in carrageenan-induced paw edema on rats. Conclusion: These results suggest that SKT has anti-inflammatory activities in both in vitro and in vivo models.

Review on Case Reports of Syndrome differentiation and Herbal Medicine Treatment for Tic Disorder (틱 장애의 한의학적 변증 및 한약치료 치험례에 대한 고찰)

  • Lee, Ye Ji;Jeon, Ju Hyun;Kim, Eun seok;Kim, Young Il
    • Journal of Haehwa Medicine
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    • v.28 no.1
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    • pp.13-25
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    • 2019
  • Objectives : This study analyzed domestic case reports of syndrome differentiation and herbal medicine treatment for tic disorder published from 2000 to 2018 and aimed to seize the latest trend of Korean herbal medicine treatment according to syndrome differentiation. Methods : We searched herbal medicine treatment of tic disorder through five major Korean academic literature databases; NDSL, KTKP, KISS, RISS, DBPIA. Results : 12 articles were included in this study from 49 articles. These studies were analyzed by year, evaluation criteria, Korean treatments, treatment effects, syndrome differentiation, herbal medication, duration of medication, and type of herbal medicine. Treatment results were assessed by YGTSS. Most cases accompanied Korean integrative treatments and only one case report used herbal medicine alone. Most common type of syndrome differentiation for patients was spleen. Duration of medication varied according to each case and decoction was the most used type of herbal medication. Conclusions : It has been reported that herbal medicine treatment according to the syndrome differentiation could be effective in treating tic disorder. This study suggests that additional studies will be required to justify classification of syndrome differentiation and the sole effectiveness of herbal medicine on tic disorder.

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Study on newly established herbal markets;Focused on the origin and growth of Jecheon Herbal Market (근대 신설 약령시 연구;제천약령시의 발생과 성장을 중심으로)

  • Kwon, Oh-Min;Lee, Jeong-Hwa;Ha, Jeong-Yong;Park, Sang-Young;Ahn, Sang-Woo
    • Korean Journal of Oriental Medicine
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    • v.14 no.1
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    • pp.41-48
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    • 2008
  • This article examines the origin and growth of Jecheon Herbal Market(JHM). JHM was established in 1928 at the Jecheon Market Main causes of the growth of JHM is widely considered as the fact that it was located to the sources of herbal product, domestic or wild, and its convenient access in transportation aspect. Since the Independence of Korea, the control of the import of herbal medications from abroad served for the main factor of JHM's growth. Nowadays JHM is estimated as second to Gyungdong Herbal Market in total. However, among production-oriented markets it has been ranked first.

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Investigation for the Induction of Quality Inscription System with Herbal Medicine (한약재 품질 표시 제도의 도입을 위한 조사)

  • Lee, Mi-Young;Kim, Ho-Kyoung;Jeon, Won-Kyung;Jung, Gye-Jin;Ju, Young-Seung;Ju, Young-Seung;Ko, Byoung-Seob
    • Korean Journal of Oriental Medicine
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    • v.6 no.1
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    • pp.59-68
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    • 2000
  • The purpose of this study is to encourage the circulation of good quality of oriental medicine and to improve national welfare. Investigation for the induction of quality inscription system was conducted by mail and interview. The data were analyzed by SAS. The major results were as follows: The portion of subjects agree to necessity of quality inscription was 78.5%. In the question of side effect against quality inscription, the rate of negative was 67.7%. The responses answered that the necessity of quality inscription was not economical profit but authority of knowledge and improvement on health(37.8%), established market for herbal medicine(34.7%) and effect of clinical care(23.9%), respectively These results might be useful information for establishing of quality inscription system for herbal medicine.

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Effects of High Frequency Herbal Medication Administrations on the Liver Functions in Rats - Focusing on Sipjeondaebo-tang, Yukmaijihwang-tang, Bojungikgi-tang, and Ojeoksan - (다용 한약처방 투여가 흰쥐의 간기능에 미치는 영향 - 십전대보탕, 육미지황탕, 보중익기탕 및 오적산을 중심으로 -)

  • Han Yong-Joo;Lee Sun-Dong;Choi Jong-Hwan;Park Jong-Goo;Jang In-Soo;Park Hae-Mo
    • The Journal of Korean Medicine
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    • v.27 no.1
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    • pp.78-90
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    • 2006
  • Background : Traditional herbal medicine is used extensively among the Korean populations, and other Asian countries employ similar therapies as well. In recent years, extensive focus was laid on adulteration of the herbal medicine with liver damage. The use of herbal preparations as remedies for various medical conditions has continuously increased in Korea. Large proportions of Korean patients use herbal medicinal products, folk remedies, and health food. However, studies on the safety of herbal products are conducted on a less than sufficient basis even in the countries like Korea where herbal medicine is being used extensively. Some of the reports on the safety of herbs were done by the doctors of western medicine but lack of knowledge and misclassification led to misunderstandings. Objectives : This study aims to verify the evidences on safety of frequently used 4 herbal medications (Sipjeondaebo-tang, Bojungikgi-tang, Ohjeok-San, Yukmaijihwang-tang) in the lab animal model. Methods : Sprague-Dawley rats was treated by 4 herbal medications during 31 days. After 1 month, we checked body weight, liver weight, and serum enzyme associated with liver function. Results : There is no significant difference in body weight and liver weight after 1 month of administrations. In all experimental groups, no abnormal findings was observed in histotogical research and lab liver Functions test(AST, ALT etc). Conclusions : These four herbal medications, frequently used in oriental medicine clinics and hospitals, are safe from hepatoxic events in the lab animal model.

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Six Cases of Acne Vulgaris Treated by Sasang Constitutional Treatment with Herbal Steam Therapy (사상체질처방과 훈증요법을 병행한 여드름 치험 6례)

  • Kim, Ki-Bae;Kim, Tae-Wook;Choi, Sung-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.29 no.2
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    • pp.130-141
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    • 2016
  • Objectives : This study was to performed to investigate the effect of herbal steam therapy on acne vulgaris. Methods : 6 patients with acne vulgaris were treated with korean medicine therapy (herbal medicine and acupunture) including herbal steam therapy. We evaluated the effect by Korean Acne Grading System(KAGS) and Pictures. Results : After treatment, the KAGS Grade of all patients treated with korean medicine therapy including herbal steam therapy is 1. Based on this, we could find that korean medicine therapy including herbal steam therapy is effective and available to ameliorate for the symptoms of acne vulgaris. Conclusions : This clinical cases study shows us that korean medicine therapy including herbal steam therapy seem to be effective to improve symptoms of acne vulgaris. Further studies will be needed to identify herbal steam therapy is beneficial to acne vulgaris.

New Approach for Herbal Formula Research: Network Pharmacology (방제 연구를 위한 새로운 접근: 네트워크 약리학)

  • Han, Sang Yong;Kim, Yun Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.30 no.6
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    • pp.385-396
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    • 2016
  • It is a fact that the existing pharmacological research method is difficult to explain the effect and mechanism of action of herbal formula of Korean medicine. We are now very pleased with the development of modern science and the development of a methodology for studying herbal formula characterized by network targets and multi-component therapeutics over the human body. In this review, systems pharmacology or network pharmacology is demonstrated how these are applied to explain the effectiveness of herbal medicine. The post-genomic era provides a unique opportunity for the two fields to understand and benefit from each other. In particular, recent research trends, research methodology, useful databases and results of research on herbal formula are introduced. China already has a policy of scientific development of traditional chinese medicine (TCM) and the development of Chinese medicine industry with a focus on herbal formula research at national level, and in Korea, it is urgent to support and nurture the methodology appropriate to the characteristics of the herbal formula in order to study the safety and efficacy of Korean medicine.

A Elementary Study on Protect Intellectual Property of Herbal Medicines (한약제제의 권리보호에 대한 초보적인 고찰)

  • Kim, Yun-Kyung;Ahn, Sang-Woo;Kim, Hong-Jun;Choi, Hwan-Soo
    • Korean Journal of Oriental Medicine
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    • v.10 no.1
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    • pp.81-95
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    • 2004
  • The discussion of intellectual property protection with TK, GR in WIPO begin Herbal medicines get a important basis in a development of modern new medicine. For the protection of intellectual property, we set up this study. For the protection of intellectual property with herbal medicines, We analyze as follows. First, we analyze the specific theory and character of traditional herbal medicines. Second, we analyze the existing system on protecting them in Korea. The intellectual property protection with herbal medicines must maintain the specific character of that. We must select the basic traditional herbal medicines. The next, we must protect from intellectual property on add and subtract, combine, create of the traditional herbal medicines. In order that we must construct database on the Herbal medicines.

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