• Title, Summary, Keyword: Lavandula angustifolia

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Effects of Lavandula angustifolia Aroma on Electroencephalograms in Female Adults with Sleep Disorders (라벤더향이 수면장애가 있는 여자 성인의 뇌파에 미치는 영향)

  • Jung, Han-Na;Choi, Hyun-Ju
    • Journal of Life Science
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    • v.22 no.2
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    • pp.192-199
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    • 2012
  • This study investigated the effects of Lavandula angustifolia (L. angustifolia) aroma on the brain electrical activity evaluated by electroencephalogram (EEG) in female adults with sleep disorders. The subjects were 28 healthy female adults and their sleep disorders were classified by the Pittsburgh Sleep Quality Index. EEG electrodes were attached at the frontal (F3, F4), temporal (T3, T4), occipital (O1, O2), parietal (P3, P4), reference, and ground regions according to the International 10-20 system. Subjects were exposed to the L. angustifolia aroma for 3 min. Results showed that L. angustifolia aroma decreased the occipital and parietal alpha powers, and increased the frontal theta power and occipital beta power in subjects with good sleep quality. On the other hand, L. angustifolia aroma increased the theta power in the all cranial regions after aroma treatment in subjects with poor sleep quality. In conclusion, L. angustifolia aroma diminishes a state of wakefulness in the brain and helps individuals to fall asleep. Therefore, L. angustifolia aroma may have beneficial effect for female adults with sleep disorders.

Effects of Lavandula angustifolia aroma on electroencephalogram in male adults with good sleep quality and poor sleep quality (라벤더향이 수면질이 좋은 남자 성인과 수면질이 나쁜 남자 성인의 뇌파에 미치는 영향)

  • Jung, Hanna;Choi, Hyun Ju
    • Science of Emotion and Sensibility
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    • v.15 no.4
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    • pp.453-468
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    • 2012
  • This study investigated the effects of Lavandula angustifolia (L. angustifolia) aroma on the brain electrical activity evaluated by an electroencephalogram (EEG) in the male adults since many researches were performed with females and few with males. Sleep quality of 35 male adults were analyzed by Pittsburgh sleep quality index, and they were divided into two groups of good sleep quality and poor sleep quality. EEG electrodes were attached at the frontal (F3, F4), temporal (T3, T4), occipital (O1, O2), and parietal (P3, P4) regions according to the International 10-20 system. EEG was measured for 3 min per each period of before, during, and after L. angustifolia aromatherapy. Subjects with good sleep quality showed increases in the delta power at the parietal region of both cerebral hemispheres and in the theta power at the temporal region of right hemisphere (p<0.05), and a decrease in the alpha at the parietal region of both cerebral hemispheres (p<0.05). And subjects with poor sleep quality showed increases in the delta power at the frontal region of left cerebral hemisphere and in the theta power at the frontal region of both hemispheres (p<0.05). It is concluded that L. angustifolia aroma has effects on decreasing an awakening status related-brain wave and increasing the sleep status related-brain waves in the male adults with good sleep quality, and has also effects on increasing the sleep status related-brain waves in the male adults with poor sleep quality.

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Anti-Aging Activity of Lavandula angustifolia Extract Fermented with Pediococcus pentosaceus DK1 Isolated from Diospyros kaki Fruit in UVB-Irradiated Human Skin Fibroblasts and Analysis of Principal Components

  • Ha, Ji Hoon;Kim, A Rang;Lee, Keon-Soo;Xuan, Song Hua;Kang, Hee Cheol;Lee, Dong Hwan;Cha, Mi Yeon;Kim, Hye Jin;An, Mi;Park, Soo Nam
    • Journal of Microbiology and Biotechnology
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    • v.29 no.1
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    • pp.21-29
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    • 2019
  • The effects of Lavandula angustifolia extract fermented with Pediococcus pentosaceus DK1 on UVB-mediated MMP-1 expression and collagen decrease in human skin fibroblasts were determined, and the conversion of its components was also analyzed. Fermentation was performed at varying L. angustifolia extract and MRS medium concentrations, and optimal fermentation conditions were selected. L. angustifolia extracts showed decreased cytotoxicity after fermentation in the fibroblasts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extract showed MMP-1 expression 8.2-14.0% lower than that in UVB-irradiated fibroblasts treated with non-fermented extract. This was observed even at fermented extract concentrations lower than those of non-fermented extracts. Fibroblasts treated with fermented L. angustifolia extract showed 20% less reduction in collagen production upon UVB irradiation than those treated with non-fermented extracts. UVB-irradiated fibroblasts treated with fermented L. angustifolia extracts showed 50% higher inhibition of ROS generation than those treated with non-fermented extract. Luteolin and apigenin glycosides of L. angustifolia were converted during fermentation, and identified using RP-HPLC and LC/ESI-MS. Therefore, the effects of L. angustifolia extract on MMP-1 expression and collagen decrease in UVB-irradiated human skin fibroblasts were increased through fermentation by P. pentosaceus.

Composition Analysis and Antioxidant Activities of the Essential Oil and the Hydrosol Extracted from Rosmarinus officinalis L. and Lavandula angustifolia Mill. Produced in Jeju (제주산 로즈마리와 라벤더(Rosmarinus officinalis L., Lavandula angustifolia Mill.)로부터 추출한 essential oil과 hydrosol의 성분 분석 및 항산화 활성)

  • Jeon, Deok Hyeon;Moon, Jeong Yong;Hyun, Ho Bong;Kim Cho, Somi
    • Journal of Applied Biological Chemistry
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    • v.56 no.3
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    • pp.141-146
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    • 2013
  • Constituents of the essential oil (EO)s and hydrosol of rosemary (Rosmarinus officinalis L.) and lavender (Lavandula angustifolia Mill.) were analyzed by gas chromatography-mass spectrometry (GC-MS). The identified major constituents were ${\alpha}$-pinene (40.96%), camphor (34.44%), verbenone (45.31%), and camphor (67.04%) in rosemary EO, lavender EO, rosemary hydrosol, and lavender hydrosol, respectively. The antioxidant activity of EO and hydrosol extracted from rosemary and lavender were evaluated. Both EO showed di(phenyl)-(2,4,6-trinitrophenyl) iminoazanium (DPPH) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) free radical scavenging activities as well as $Fe^{2+}$ ion chelating activity but no alkyl radical scavenging activity. Rosemary EO showed higher DPPH radical scavenging activity than lavender, whereas lavender EO showed higher $Fe^{2+}$ ion chelating activity. Both rosemary and lavender hydrosols showed alkyl radical scavenging activity, but only lavender hydrosol showed an activity on $Fe^{2+}$ chelating assay. Both rosemary and lavender hydrosols also protected the dermal fibroblast and the HaCaT keratinocytes against $H_2O_2$-induced cytotoxicity.

Antioxidant Activity and Component Analysis of Fermented Lavandula angustifolia Extracts (라벤더 발효추출물의 항산화 활성과 성분 분석)

  • Park, Soo-Nam;Ahn, You-Jin;Won, Bo-Ryoung;Kang, Myung-Kyu;Kim, Jai-Hyun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.2
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    • pp.125-134
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    • 2009
  • In this study, the antioxidative effects, inhibitory effects on tyrosinase, and component of non-fermented and fermented Lavandula angustifolia extracts were investigated. The ethyl acetate fraction of fermented extract (5.95 ${\mu}g/mL$) showed the most prominent the free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity ($FSC_{50}$). Reactive oxygen species (ROS) scavenging activities ($OSC_{50}$) of L. angustifolia extracts on ROS generated in $Fe^{3+}-EDTA/H_2O_2$ system were investigated using the luminol-dependent chemiluminescence assay. The ethyl acetate fraction of fermented extract (1.45 ${\mu}g/mL$) showed the most prominent ROS scavenging activity. The protective effects of extract/fractions of L. angustifolia on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The L. angustifolia extracts suppressed photohemolysis in a concentration dependent manner (1 ${\sim}$ 50 ${\mu}g/mL$). The inhibitory effect of L. angustifolia extracts on tyrosinase was investigated to assess their whitening efficacy. Inhibitory effects ($IC_{50}$) on tyrosinase were determined with ethyl acetate fraction of L. angustifolia extract (144.80 ${\mu}g/mL$) and ethyl acetate fraction of fermented extract (122.40 ${\mu}g/mL$). Fractions of ethyl acetate and fermented extracts showed both 3 band in TLC and 3 peaks, 2 peaks in HPLC (340 nm), respectively. In each chromatography, fractions of ethyl acetate both from non-fermented and fermented L. angusfifolia have rosmarinic acid in common. These results indicate that the component and content of non-fermented and fermented extracts of L. angustifolia are different. Both of the extract of L. angustifolia can be used as an antioxidant.

Verification of lavender(Lavandula angustifolia cv.Hidcote) and lawn(Zoysia japonica Steud.)'s Curative Effect, as a Green Space Composition Factor (녹지구성 인자로써 라벤더(Lavandula angustifolia cv.Hidcote)와 잔디(Zoysia japonica Steud.)의 치유적 효과)

  • Yutaka, Iwasaki;Kim, Yu-Yeong;Cho, Tae-Dong
    • Journal of Environmental Science International
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    • v.21 no.12
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    • pp.1487-1494
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    • 2012
  • This study has been carried out to verify curative effect of lavender and lawn, a green space composition factor. Thus, the physiological index value of blood pressure, heart rate and salivary amylase were measured with object of 16 women in their 20~30s for stress relaxation effect at lavender garden and lawn square, and impression assessment upon SD method as for psychological value was performed in this study. And a survey was conducted on necessity and reason of urban green space with object of 345 men and women urban workers. As a result of variance analysis between groups and multi test of Turkey upon object place, the blood pressure was lowered the same at lavender garden and lawn square, and especially, high blood pressure was greatly lowered to 30 mmHG at lavender garden. On the other hand, low blood pressure group showed the tendency of a little increasing at the same places. And for the pulse, there was difference between high blood pressure group and normal group at the same places. To conclude, at lavender garden and lawn square the blood pressure was made to be lowered when it's high, and when it's low, the effect of returning to sound status, the function of increasing, was verified. In case of impression assessment upon SD method, the lawn square was assessed as resting place and lavender garden diversional place. And over 90% of urban workers responded to the green space's necessity and curative effect, diversion and resting place were adopted for the reason in high-ranking items. As above the green space pattern that urban workers require and curative effect of lavender garden and lawn square were verified. Therefore, the functional green space plan is required, which curative effect, diversion and resting place are considered, for the future green space plan design.

Anti-Aspergillus Activities of Plant Essential Oils and Their Combination Effects with Ketoconazole or Amphotericin B

  • Shin, Seung-Won
    • Archives of Pharmacal Research
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    • v.26 no.5
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    • pp.389-393
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    • 2003
  • The essential oils from Cedrus atlantica, Styrax tonkinensis, Juniperus communis, Lavandula angustifolia, Melaleuca alternifolia, Pelargonium graveolens, Pogestemon patchouli and Rosmarinus officinalis were analyzed by GC-MS. Antifungal activities of the oils were investigated by disk diffusion assay and the broth dilution method against Aspergillus niger and A. flavus. The effects of geraniol and the essential oil fraction from P. graveolens on the antifungal activity of amphotericin Band ketoconazole were examined using a checkerboard microtiter assay against both Aspergillus fungi. Most of the tested essential oils, with the exception of C. atlantica, J. communis, and P. patchouli, significantly inhibited growth of A. niger and to a lesser extent that of A. fIavus, with MICs (minimal inhibitory concentrations) in the range 0.78-12.5 mg/mL. The essential oil fraction of P. graveolens and its main components, geraniol and citronellol, exhibited additive effects with amphotericin B and with ketoconazole against both Aspergillus species, resulting in fractional inhibitory concentration (FIC) indices ranging from 0.52 to 1.00.

Study on antifungal activity of herb oils against Trichophyton spp

  • Shin, Seung-Won;Kim, Ji-Hyun;Lim , Sook;Pyun, Mi-Sun
    • Proceedings of the PSK Conference
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    • pp.384.1-384
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    • 2002
  • The antifungal activities of the essential oils from Citrus borgamia. Ciderus atlantica. Cymbopogon ditratus, Eucalyptus globulus. Juniperus communis. Lavandula angustifolia. Melaeuca aterinfolia. Pelargonium graveolens. Pogestemon patchouli. Rosmarinus officinalis. Styrax tonkinensis. and Thymus vulgaris, which are recommended for the treatment of microbial infections in aromatherapy and complementary medicines. were tested against Trichophyton spp. The activities were measured by broth dilution method and disk diffusion assay. As the results, most of the test oils inhibited growth of T. tonsurans. T.mentagrophytes. T. ferugineum. and T. rubrum. Eapecially, the essential oils from C. atlantica. C. ditratus. e. globulus, and P. graveolens showed the strongest activity among the tested herb oils showing MICs between < 0.09 and 0.39 mg/ml.

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Antifungal Activities of Herbal Essential Oils and Combination Effects with Ketoconazole against Candide spp. (수종 허브정유의 Candida속 진균에 대한 억제 활성 및 Ketoconazole과의 병용효과)

  • 신승원
    • YAKHAK HOEJI
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    • v.46 no.3
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    • pp.203-207
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    • 2002
  • The antifungal activities of the essential oils from Anthemis nobilis, Ciderus atlantica, Juniperus communis, Lavandula angustifolia, Pelargonium graveolens, Pogestemon patchouli, Rosmarinus officinalis, and Styrax tonkinensis which are recommended for the treatment of microbial infections in aromatherapy and complementary medicines were tested against Candida spp. The activities were measured by broth dilution method and disk diffusion assay. Most of the test oils inhibited growth of Candida albicans, C. utilis and C. tropicalis. Especially, the essential oil from Pelargonium graveolens and its main component, citronellol showed the strongest activity among the herbs except benzoic acid from Styrax tonkinensis which is well-known antimicrobial compound. As a result of checkerboard microtiter test. synergistic effect of citronellol, was shown when the component was combinated with ketoconazole, displaying a fractional inhibiting concentration (FIC) index of 0.37 against C. albicans.

Recovery Effect of Blending Oil on Skin Barrier Damaged by Atopic Dermatitis (아토피피부염의 손상된 피부장벽에 대한 혼합오일의 회복 효과)

  • Seo, Young Mi
    • Journal of East-West Nursing Research
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    • v.20 no.1
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    • pp.57-62
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    • 2014
  • Purpose: The purpose of this study was to evaluate the effect of a mixture of ARL oils, Agastache rugosa, Rosemarinu officinalis, and Lavandula angustifolia on atopic dermatitis (AD) model on NC/Nga mice. Methods: Twenty-four, 6 week-NC/Nga mice were assigned to a control group (C, n=8), an AD-induced group (E, n=8), and an ARL oil-treated group (E, n=8) that had two treatments per day for 6 days. Epidermis thickness, total amount of collagen and expression of TGF-${\beta}$ in the AD induced mice were measured. Results: The ARL oil-treated group showed a significantly decreased epidermis thickness, and a greater amount of collagen and expression of TGF-${\beta}$ compared with the AD-induced group. Conclusison: ARL oil may be a putative resources for care or treatment of AD in the view of nursing intervention.