• Title, Summary, Keyword: Measuring glucose concentration

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Application of Radio Frequency Microwave Technique for Glucose Detection (포도당 검출을 위한 라디오 주파수 마이크로파의 적용)

  • Kim Tae-Woo;Park Byoung-Soo;Cho Dong-Uk;Han Khil-Sung;Cho Tae-Kyung
    • The Journal of the Korea Contents Association
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    • v.4 no.4
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    • pp.171-178
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    • 2004
  • Radio frequency (RF) microwave can be used to predict glucose concentration in a sample. This paper presents preliminary results in determining the concentration by measuring relative permittivity in the solutions of distilled water, saline, human serum, and human blood containing glucose. It was shown that the microwave method has larger penetration depth of about 100times of NIR, than NIR technique in measuring glucose concentration for the tissue like a human muscle. The larger penetration depth of the method has advantages because it is more useful to detect glucose in a human body non-invasively. In the experiments, sensitivity for detecting glucose concentration in blood solutions was almost 57mg/dl at the frequency of approximately 5.8GHz.

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On-line Monitoring of a Glucose Concentration on a Fermentation Process of Wine for an Automatic Control of a Fermentation Process (발효공정 자동제어를 위한 포도주 발효 중 포도당 농도 온라인 측정)

  • Song, Dae-Bin
    • Journal of Biosystems Engineering
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    • v.33 no.4
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    • pp.276-281
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    • 2008
  • A flow injection analysis method (FIA), which analyzes sample conditions after injecting a sample and reagents into a continuous stream, are recognized as the most adequate analyzing method according to the increase of sampling frequency, the decrease of measuring time and the diversity of measuring targets. Specially, the FIA is considered to be used effectively for the control of a fermentation process to produce fermentation food and useful microbial production by activation of a fermentation industry for development of biological materials. In this study, a flow injection analysis sensor unit was developed for on-line monitoring of the fermentation process. The performance was verified by on-line measuring the concentration of glucose of the fermentation process of wine. The glucose concentrations of the samples were measured every 12 hours during the whole fermentation process and compared with those by a HPLC. The concentration relative errors of glucose on the fermentation process of wine showed below 30% within 72 hours and over 50% after the 72 hours. The sensor unit had potential to on-line monitoring of the fermentation process but some problems to overcome for an commercial application.

Electrochemical Determination of Glucose Concentration Contained in Salt Solution (소금용액에 포함된 글루코오스 농도의 전기화학적 측정)

  • 김영한
    • Journal of Korean Port Research
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    • v.14 no.4
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    • pp.475-479
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    • 2000
  • A possibility of the implementation of a quartz crystal sensor to the determination of chemical oxygen demand is examined by checking the electrochemical behavior of the sensor in a glucose solution. Since the surface of a quartz crystal has to be oxidized, a relatively active metal is coated on the surface of a usual 9 MHz AT-cut crystal. The electrochemical behavior is investigated by measuring the changes of current, resonant frequency and resonant resistance while a constant potential is applied. The crystal is installed in a specially designed container, and a quartz crystal analyzer is utilized to measure the frequency and resistance simultaneously. The variations of the measurements are examined at different concentrations of glucose solution, and a proper relation between the concentrations of glucose solution, and a proper relation between the concentration and the measurements is analyzed. As a result, it is found that a linear relation between the concentration of less than 900 ppm and the peak current when a constant potential of -180 mV (SSCE) is applied. The relation can be utilized for the determination of glucose concentration in sea water, and considering a direct relation between gluose concentration and chemical oxygen demand tells a possibility of the measurement of chemical oxygen demand using quartz crystal oscillators.

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Real-time Monitoring of Glucose Using a Differential Refractive Index Detector (시차 굴절률 측정에 의한 실시간 글루코오스 모니터링)

  • 정진갑;이명희;최은경
    • Textile Coloration and Finishing
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    • v.16 no.2
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    • pp.47-51
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    • 2004
  • A differential refractive index detector was used for monitoring glucose contents in textile processing solutions. The sensitivity of the device was high enough to measure 0.05% aqueous glucose solution that could not be measured by normal refractive index measurement. The device was set to monitor glucose concentration continuously in real time by measuring differential refractive index and calibrated by standard glucose solutions in a range of 0.1 to 1.0%. The possibility of industrial application of the device was demonstrated by real-time monitoring of glucose concentration in textile processing solutions such as desizing bath and cellulase treatment bath. Both of solutions contained glucose as a major degraded product. The device would be able to control the weight loss of cellulosic fiber during cellulase treatment since the amount of degraded products in a processing bath is proportional to its weight loss.

Comparison of Glucose Concentration of Tracheal Secretions by Measuring Times and Feeding Methods in Enterally Fed Patients (폐흡인군과 비폐흡인군의 측정 시간대 별 기관분비액 당농도와 경장영양액 제공 방법 비교)

  • Kim, Hwa Soon;Yoon, Mi Ja
    • Korean Journal of Adult Nursing
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    • v.18 no.5
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    • pp.718-726
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    • 2006
  • Purpose: The purpose of this study was to investigate differences between a pulmonary aspiration group and a non-pulmonary aspiration group in glucose concentration of tracheal secretions by measuring time and feeding methods. Method: The subjects were 36 ICU patients who were receiving formula via nasogastric tubes and had endotracheal tubes or tracheostomy tubes. Tracheal secretions were collected by connecting suction traps to a suction catheter in three different times(within 1 hour after feeding, between 1 to 2 hours after feeding, and between 2 to 3 hours after feeding) for 2 days, overall six times. Glucose concentration of tracheal secretions was measured with the glucometer(Accucheck II). Results: Glucose concentration of tracheal secretions increased in progression after feeding. The mean of specimens collected last(between two to three hours after feeding) was shown to be the highest value(M=61.61mg/dl) in the pulmonary aspiration group. Significantly(p=.000) more subjects(94.44%) in the pulmonary aspiration group received formula via a 50cc syringe than those in the non-pulmonary aspiration group(22.22%). Conclusion: Critically ill patients may need more time for head-elevation after tube feeding to prevent pulmonary aspiration. In practice, enteral formula should not be given the patients via a $50_cc$ syringe anymore, instead a feeding bag or infusion pump should be used to prevent pulmonary aspiration.

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Application for Measuring the Glucose, Ammonia nitrogen, and Tylosin Concentration using Near Infrared Spectroscopy

  • Kim, Jong-Soo;Cho, Hoon
    • Journal of environmental and Sanitary engineering
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    • v.23 no.2
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    • pp.19-25
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    • 2008
  • For measurement of tylosin, ammonia nitrogen, and glucose concentration during the culture of Streptomyces fradiae using Near Infrared Spectroscopy, the calibration using various mathematical models was performed and then, based on the linear model, the validation was carried out. In the case of sucrose concentration using the MLR method, the Standard Error of Prediction and Multiple correlation coefficient were 1.97, and 0.991, respectively. In the case of ammonia nitrogen concentration using the PLSR method, the Standard Error of Prediction and Multiple correlation coefficient were 0.13, and 0.990, respectively. In the case of tylosin concentration using the PLSR method, the standard Error of Prediction and Multiple correlation coefficient were 0.54, and 0.984, respectively.

Influence of Other Blood Components in Predicting Glucose Concentration using Design of Experiment (실험계획 법에 의한 혈중 글루코즈 측정 시 타 성분의 영향 분석)

  • 김연주;윤길원;전계진
    • Journal of Biomedical Engineering Research
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    • v.22 no.6
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    • pp.497-502
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    • 2001
  • Influence of other blond components on measuring glucose concentration was analyzed B)food phantom containing five major components was made. The prediction model was developed based on the measurement of absorption spectra including the first overtone glucose band, i.e.. 1500 ∼ 1850 nm. The concentrations were Predicted using the Partial least squares regression. Factor analysis based on Design of Experiment was Performed to study the influence of other components in predicting glucose concentration. Triglyceride does not influence. Albumin and globulin haute minor effects. However, hemoglobin showed substantial response and the compensation of hemoglobin concentration appears to be required for the model of glucose measurement.

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Effect of Gaewool-Whadam-Jian on Transport Ability of Small Intestine and Secretion of Gastric Juice in the Rat (개울화담전(開鬱化痰煎)이 흰쥐 소장(小腸) 수송능(輸送能)과 위액분비에 미치는 영향)

  • Kim Hee-Chul;Lee Young-Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.5
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    • pp.1330-1336
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    • 2005
  • This study was carried out to investigate the motor activity and glucose transport and metabolism of Gaewool-Whadam-Jian(GWJ) in rat gastro-intestinal tract. The motor activity of the rat gastro-intestinal tract has been investigated by means of measuring barium sulfate passage degrees. Atropine treatment significantly delayed barium sulfate transit, and GWJ pretreatment increased intestinal motor activity, but not significant. GWJ administration showed no toxicity to kidney and liver. Transport and metabolism of glucose were studied in everted sac of rat small intestine with incubation under several conditions. The transport and metabolism of glucose were greater at jejunum than ileum. So, everted jejunum of rat were used to study the effect of GWJ. When GWJ were treated, the concentration of glucose were higher than untreated group. This result was thought to be influenced by the glucose in GWJ. When 2, 4 dinitrophenol and phlorizin were treated, the transport and metabolism of glucose were decreased, but GWJ treated together, the concentration of glucose in serosal solution increased. Gastric juice secretion and total acidity significantly decreased by administration of GWJ through duodenum region. The mechanism of effect of GWJ was still unidentified, Dut through continuous investigation, the effect of GWJ should be investigated.

Blood Glucose Measurement Principles of Non-invasive Blood Glucose Meter: Focused on the Detection Methods of Blood Glucose (무채혈 혈당 측정기의 혈당 측정 원리: 혈당 검출방법 중심으로)

  • Ahn, Wonsik;Kim, Jin-Tae
    • Journal of Biomedical Engineering Research
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    • v.33 no.3
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    • pp.114-127
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    • 2012
  • Recent technical advancement allows noninvasive measurement of blood glucose. In this literature, we reviewed various noninvasive techniques for measuring glucose concentration. Optical or electrical methods have been investigated. Optical techniques include near-infrared spectroscopy, Raman spectroscopy, optical coherence technique, polarization, fluorescence, occlusion spectroscopy, and photoacoustic spectroscopy. Electrical methods include reverse iontophoresis, impedance spectroscopy, and electromagnetic sensing. Ultrasound, detection from breath, or fluid harvesting technique can be used to measure blood glucose level. Combination of various methods is also promising. Although there are many interesting and promising technologies and devices, there need further researches until a commercially available non-invasive glucometer is popular.

Optimization of Maillard Reaction between Glucosamine and Other Precursors by Measuring Browning with a Spectrophotometer

  • Ogutu, Benrick;Kim, Ye-Joo;Kim, Dae-Wook;Oh, Sang-Chul;Hong, Dong-Lee;Lee, Yang-Bong
    • Preventive Nutrition and Food Science
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    • v.22 no.3
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    • pp.211-215
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    • 2017
  • The individual Maillard reactions of glucose, glucosamine, cyclohexylamine, and benzylamine were studied at a fixed temperature of $120^{\circ}C$ under different durations by monitoring the absorbance of the final products at 425 nm. Glucosamine was the most individually reactive compound, whereas the reactions of glucose, cyclohexylamine, and benzylamine were not significantly different from each other. Maillard reactions of reaction mixtures consisting of glucosaminecyclohexylamine, glucosamine-benzylamine, glucose-cyclohexylamine, and glucose-benzylamine were also studied using different concentration ratios under different durations at a fixed temperature of $120^{\circ}C$ and pH 9. Maillard reactions in the pairs involving glucosamine were observed to be more intense than those of the pairs involving glucose. Finally, with respect to the concentration ratios, it was observed that in most instances, optimal activity was realized, when the reaction mixtures were in the ratio of 1:1.