• 제목, 요약, 키워드: Osteoporosis

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폐경기 이후 여성의 골다공증 위험요인 (The Risk Factors of Osteoporosis in Korean Postmenopausal Women)

  • 이혜영;박원숙
    • 성인간호학회지
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    • v.21 no.3
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    • pp.303-313
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    • 2009
  • Purpose: The purpose of this study was to investigate bone mineral density(BMD) and identify risk factors of osteoporosis in Korean postmenopausal women. Methods: The subjects consisted of 328 women. The BMD of the calcaneus were measured with peripheral dual energy x-ray absorptiometry. The risk factors were collected by a self-report standardized questionnaire. The differences among the osteoporosis, osteopenia, and normal group were compared by one way analysis of variance test, Scheffe's multiple comparison tests and Logistic regression. Results: The average age was 65 years old and the average T-score was 28.7% with osteoporosis. The Risk factors of osteoporosis were inclined by 24% in age (OR = 1.24, CI = 1.16 ~ 1.31), 53% in menarchal age (OR = 1.53, CI = 1.24 ~ 1.88), 3.5 times in vegetarian (OR = 3.52, CI = 1.66 ~ 7.47), 2 times in small-bowel disease (OR = 2.01, CI= 1.03 ~ 3.94), 5.3 times in arthritis (OR = 5.33, CI = 1.61 ~ 17.67), 5.5 times in eating disorder (OR = 5.50, CI = 1.43 ~ 21.17), 6 times in health perception (OR = 6.08, CI = 2.30 ~ 16.06). The Risk factors of osteoporosis were reduced by 10% in weight (OR = 0.90. CI = 0.83 ~ 0.97), and 10% in menopausal age (OR = 0.90. CI = 0.84 ~ 0.98). Conclusion: The risk factors of osteoporosis were in the general characteristics, menstrual history, history of disease, life style & diet, and health perception. Eating disorder and health perception are highest on the risk factor of osteoporosis in Korean postmenopausal women.

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High dairy products intake reduces osteoporosis risk in Korean postmenopausal women: A 4 year follow-up study

  • Park, Seon-Joo;Jung, Ji Hye;Ki, Myung-Sunny;Lee, Hae-Jeung
    • Nutrition Research and Practice
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    • v.12 no.5
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    • pp.436-442
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    • 2018
  • BACKGROUND/OBJECTIVES: The aim of this study was to identify the effect of dairy products, milk and yogurt on osteoporosis incidence among Korean postmenopausal women using prospective cohort data. MATERIALS/METHODS: Between 2001 and 2003, 10,038 participants were recruited in rural and urban areas for a baseline examination of a community-based cohort study. Of those, 1,573 postmenopausal women (aged 40-69 years at baseline) were eligible for the present study. Intakes of dairy products, milk, and yogurt were assessed using a validated semi-quantitative food frequency questionnaire. The speed of sound at the radius and tibia were measured using a quantitative ultrasound device and osteoporosis was defined based on the WHO criteria (T-score ${\leq}-2.5$). RESULTS: During the 4-years follow-up study, the cumulative incidence of osteoporosis was 18.4% (273 cases) in the radius and 33.6% (407 cases) in the tibia. The subjects with higher frequency of dairy product consumption showed a decreased risk of radius osteoporosis after adjusting for potential confounders [hazard ratio (HR) = 0.51, 95% confidence interval (CI): 0.33-0.80 for >1 time/day vs. non consumer; P for trend = 0.0027]. Similarly, high frequency of milk and yogurt consumption had a protective effect on radius osteoporosis risk [milk: HR = 0.60, 95% CI: 0.42-0.87 for > 5-6 times/week vs. non consumer (P for trend = 0.0130), yogurt: HR = 0.51, 95% CI: 0.30-0.85 for > 5-6 times/week vs. non consumer (P for trend = 0.0167)]. However, high dairy products consumption was not related with tibia osteoporosis. CONCLUSIONS: This study suggests that daily intake of dairy products could potentially reduce radius osteoporosis incidence among Korean postmenopausal women.

노인요양시설 간호제공자의 골다공증 관련 지식과 골다공증 예방활동 (Knowledge and Prevention Activity of Osteoporosis among Care Providers in Nursing Home)

  • 심하은;박미화;박명숙
    • 융합정보논문지
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    • v.9 no.12
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    • pp.71-80
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    • 2019
  • 본 연구는 노인요양시설 간호제공자의 골다공증 관련 지식과 골다공증 예방활동을 파악하기 위한 서술적 조사연구이다. 연구대상자는 S시와 Y시의 노인요양시설 4곳에서 근무 중인 간호제공자 142명이며 자료 수집기간은 2019년 7월 1일부터 7월 20일까지이다. 연구 자료는 SPSS 24.0 Version을 이용하였으며 t-test, ANOVA, Pearson's correlation coefficient를 실시하였다. 연구결과, 간호제공자의 골다공증 관련 지식은 중간수준으로 간호제공자의 학력, 골다공증 관리 교육 경험, 입소자 수, 노인 뼈 건강 중요도 인식에 따라 차이를 보였으며, 골다공증의 예방활동은 골다공증 관리 교육 경험, 노인 뼈 건강 중요도 인식에 따라 차이를 보였다. 연구대상자의 골다공증 관련 지식과 골다공증 예방활동은 정적 상관이 있었다. 따라서 노인 요양시설 간호제공자의 노인 골다공증 관리와 노인 뼈 건강 중요도 인식을 향상시키기 위한 교육 프로그램의 개발과 그에 따른 교육이 필요하며, 향후 교육의 효과를 확인하는 추가연구가 필요하다.

중년여성의 골다공증에 대한 지식과 건강신념이 골다공증 예방행위에 미치는 영향 (The Effect of the Knowledge and Health Beliefs on Osteoporosis Preventive Health Behaviors among Middle-aged Women)

  • 이종경
    • 지역사회간호학회지
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    • v.14 no.4
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    • pp.629-638
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    • 2003
  • Purpose: This study investigated the effects of knowledge and health belief on osteoporosis preventive health behaviors. Methods: The subjects of this study were 266 middle-aged women. Data were collected using a self-reporting questionnaire with 101 questions. The period of data collection was from the 3rd of January to the 28th of February 2003. Data were analyzed using SPSS 10.0 PC+ program. Results: The results were summarized as follows: 1. The average score of knowledge about osteoporosis was 16.93 out of 27. Particularly, middle-aged women had knowledge more about osteoporosis prevention measures than about risk factors. 2. Knowledge, self efficacy and barriers were significantly correlated with osteoporosis preventive health behaviors. 3. As for the relationship between subjects' general characteristics and their health preventive behaviors, the size of living district, economic status, BMI. family history of osteoporosis and perception of health status were found to have significant effects on health preventive behaviors. Conclusions: According to the results presented above, preventive health behaviors may be promoted by increasing knowledge and perceived self-efficacy as well as decreasing individuals' perceived barriers through health education.

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난소적출 랫트 비골의 시간경과에 따른 골다공증성 변화 (Time Course of Fibular Osteoporosis in Ovariectomized Rats)

  • 배춘식;박창현;엄창섭
    • Applied Microscopy
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    • v.29 no.3
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    • pp.377-382
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    • 1999
  • 12주령 랫트의 양측 난소를 적출한 후, 난소적출이 골다공증 형성에 미치는 영향을 이해하고자 본 연구를 시행하였던 바 아래와 같은 결과를 얻었다. 난소적출 후 매주 골소실이 일어나기 시작하였으며 5주부터 시작하여 7주에서는 정상대조군에 비하여 골소실의 증가가 두드러지게 나타났다. 이상의 결과를 종합해보면 랫트의 난소를 적출하여 여성호르몬의 결점을 유발하면 난소적출 후 5주부터 시작하여 7주에는 골다공증이 발생되었다.

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한국 폐경 여성의 골다공증 위험 인자에 관한 연구 (Risk Factors for Postmenopausal Osteoporosis in Korea)

  • 이동윤;구승엽;김석현;최영민;문신용;김정구
    • 한국건강관리협회지
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    • v.2 no.2
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    • pp.137-148
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    • 2004
  • Objective : To identify the risk factors for postmenopausal osteoporosis in Korea Materials and methods : Bone mineral density (BMD) at the lumbar spine and femoral neck was measured by dual energy X-ray absorptiometry in 808 apparently normal postmenopausal Korean women. Questions about life style, demographic parameters, medical history and social habits etc. were asked on these women; 2ll women with normal bone mineral density, and 597 women with osteopenia or osteoporosis. Results 'Age of >50 years, low body mass index (BMI; <18.5 kg/m2), long duration of menopause(>10 years), and previous history of fracture were associated with increased prevalence of osteopenia or osteoporosis. Women without the outside activity also showed a higher frequency of low bone mass, Risk for osteopenia or osteoporosis was low in women with high BMI (>23 kg/m2) and women with job. The prevalence of low bone mass appeared to be independent of the following parameters: socioeconomic status, familial history, smoking, drinking, exercise, previous use of oral contraceptive, coffee or milk consumption, and degree of sunlight exposure. Conclusion 'Age, BMI, duration of menopause, previous history of fracture and degree of outside activity are the risk factors for postmenopausal osteoporosis in Korea.

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의료봉사활동에서 시행한 골밀도 검사의 유소견 연구 (Research on the Bone Mineral Density Performed in Volunteer Medical Service)

  • 박창희
    • 대한디지털의료영상학회논문지
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    • v.10 no.2
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    • pp.5-10
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    • 2008
  • Thanks to recent development of science and technology, economic standard has been improved and life expectation has been gradually increased. Accordingly, disease aspect and demand for health have been changed in the concept from conventional center of disease to health improvement As the health issue in middle and senior age has also been vital in the national health, osteoporosis, one of the physical maladies occuring in these age group, is on the rise as a matter of important concern so that the researches on the osteoporosis have being accomplished actively in several medical domains. Research has been earned out for 735 examined objects, who have received medical examination of bone mineral density in the volunteer medical service of Daegu and Kyungbuk province for recent 4 years. The result indicated that serious osteoporosis prevailed over osteoporosis for male while osteopenia was majority to osteoporosis and that abnormal bone mineral density was more prominent than normal bone mineral density for both male and female. This study is to present basic data which is indispensible to preparation of senior citizen dominated society afterward, investigating the prevalence rate of osteoporosis.

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비만의 양면성: 강원도 중장년 여성의 대사증후군과 골다공증 (Two Sides of Obesity: Metabolic Syndrome and Osteoporosis in Elderly Women, Gangwon-do, Korea)

  • 장성옥;이성화;이종석
    • 보건교육건강증진학회지
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    • v.31 no.1
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    • pp.13-26
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    • 2014
  • Objectives: This study aimed to assess whether metabolic syndrome (MS) is related to osteoporosis and investigate the association between the MS components and bone mineral density (BMD). Methods: We conducted a cross-sectional study for 4,365 women aged over 50 years who completed health examination from 2008 to 2012 in Korea Association of Health Promotion Gangwon Branch. Height, body weight, waist circumference, blood pressure, fasting plasma glucose, serum lipid profiles, and BMD were measured. Results: Obesity measured as body mass index (BMI) was detrimental to all of the MS components but positively correlated with BMD at three skeletal sites (lumbar spine, femoral neck, and total hip). There were no significant differences in the MS prevalence between women without osteoporosis and those with osteoporosis. In age-adjusted analysis, women with MS had significantly higher BMD at three sites when compared to those without MS. After adjusting for BMI and age, these significances disappeared, such that MS was not associated with higher BMD. Conclusions: Our findings indicate that obesity increases the risk of MS whereas underweight increases that of osteoporosis. The association between MS and higher BMD was explained by the higher BMI in those with MS. MS may not be associated with osteoporosis.

AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells

  • Im, Jin Young;Min, Woo-Kie;Park, Min Hee;Kim, NamOh;Lee, Jong Kil;Jin, Hee Kyung;Choi, Je-Yong;Kim, Shin-Yoon;Bae, Jae-Sung
    • BMB Reports
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    • v.47 no.8
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    • pp.439-444
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    • 2014
  • Inhibition of an increase of osteoclasts has become the most important treatment for osteoporosis. The CXCR4 antagonist, AMD3100, plays an important role in the mobilization of osteoclast precursors within bone marrow (BM). However, the actual therapeutic impact of AMD3100 in osteoporosis has not yet been ascertained. Here we demonstrate the therapeutic effect of AMD3100 in the treatment of ovariectomy-induced osteoporosis in mice. We found that treatment with AMD3100 resulted in direct induction of release of SDF-1 from BM to blood and mobilization of hematopoietic stem/progenitor cells (HSPCs) in an osteoporosis model. AMD3100 prevented bone density loss after ovariectomy by mobilization of HSPCs, suggesting a therapeutic strategy to reduce the number of osteoclasts on bone surfaces. These findings support the hypothesis that treatment with AMD3100 can result in efficient mobilization of HSPCs into blood through direct blockade of the SDF-1/CXCR4 interaction in BM and can be considered as a potential new therapeutic intervention for osteoporosis.

Usefulness of Estimated Height Loss for Detection of Osteoporosis in Women

  • Yeoum, Soon-Gyo;Lee, Jong-Hwa
    • 대한간호학회지
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    • v.41 no.6
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    • pp.758-767
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    • 2011
  • Purpose: This study was done to examine the threshold value of estimated height loss at which the risk of osteoporosis increases and to verify its discriminative ability in the detection of osteoporosis. Methods: It was conducted based on epidemiological descriptive methods on 732 Korean women at a public healthcare center in Seoul between July and November 2010. ANOVA, Pearson correlation, logistic regression analysis and receiver operating characteristics (ROC) curve were used for data analysis. Results: There was an age-related correlation between bone mineral density (lumbar spine: F=37.88, p<.001; femur: F=54.27, p<.001) and estimated height loss (F=27.68, p<.001). Estimated height loss increased significantly with decreasing bone mineral density (lumbar spine: r=-.23, p<.001; femur: r=-.34, p<.001). The odds ratio for the point at which the estimated height loss affects the occurrence of osteoporosis was found to increase at a cut-off value of 2 cm and the area under ROC curve was .71 and .82 in lumbar spine and femur, respectively. Conclusion: The optimal cut-off value of the estimated height loss for detection of osteoporosis was 2 cm. Height loss is therefore a useful indicator for the self-assessment and prognosis of osteoporosis.