• Title/Summary/Keyword: Serum

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Factors Affecting Serum Lipids in Maternal and Infants Umbilical Cord Blood (산모혈과 제대혈의 혈청 지질치에 영향을 미치는 요인에 대하여)

  • 민재희;정규혁;연제덕
    • Journal of Environmental Health Sciences
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    • v.23 no.3
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    • pp.66-71
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    • 1997
  • To investigate the effect of several factors on serum lipids in maternal and infants umbilical cord blood, 111 cases of newborn infants and women delivered of a child who had delivered at hospital located in Chung-Ju city from Feb. 1, 1996 to Aug. 31, 1996 were studied. The gestational ages of cases were 37 to 42 weeks and the average maternal ages were 28.1$\pm$4.25 years old without any other medical or obstetric problems. No relationships between maternal consumption of coffee and maternal serum lipid levels were observed. However, serum total cholesterol and LDL-cholesterol levels in infants'umbilical cord were significantly increased in proportion to increasing maternal consumption of coffee. The other factors such as alcohol drinking habits and residency affected maternal serum lipid levels and not serum lipid levels in infants' umbilical cord. Delivery frequency showed very little or no effects on serum lipid levels in both maternal blood and infant's umbilical cord blood. In conclusion, maternal consumption of coffee significantly correlated with increasement of serum lipid levels in infants'umbilical cord.

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EFFECTS OF STEROID HORMONES ON SERUM SODIUM AND POTASSIUM IN PARATHYROIDECTOMIZED CHICKENS (Steroid hormone이 부갑상선 적출 수탉에 있어서 혈청쏘디움 및 포타슘 농도에 미치는 영향에 관한 연구)

  • Moon, Dong-Sun
    • The Journal of the Korean dental association
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    • v.10 no.6
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    • pp.369-372
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    • 1972
  • This study was investigated that effects of steroid hormones on serum sodium and potassium concentration in parathyroidectomized chickens. The results are as followings; 1) Serum sodium and potassium concentration in SHAM-controls were unchanged. 2) In parathyroidectomized chickens, serum potassium level increased more than that of control and serum sodium level appeared no change in each group. 3) In group of administration of cortisone in parathyroidectomized chickens, serum potassium level increased generally more than that of control and serum sodium level appeared no change in each group. 4) In group of administration of testosterone in parathyroidectomized chickens, serum potassium level increased generally more than that of control and serum sodium level revealed no change in each group.

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The effect of Hwangkikunjungtang and GamiHwangkikunjoongtang on the recovory of exercise induced fatigue (황기건중탕 및 가미황기건중탕이 흰쥐의 운동(運動) 피로회복(疲勞恢復)에 미치는 영향(影響))

  • Park, Dong-Il;Cho, In-Joo
    • The Journal of Korean Medicine
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    • v.18 no.2
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    • pp.155-166
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    • 1997
  • The following are the results of the experimental studies of Hwangki kunjoongtang and GamiHwangkikunjoongtang on the recovory of exercise induced fatigue. Hwangkikunjoongtang showed remarkable effects on the decrease of oxygen consumption, serum lactate levels, serum LDH activities, serum FFA levels, and on the increase of serum triglyceride levels. GamiHwangkikunjoongtang showed remarkable effects on the decrease of serum lactate levels, serum LDH activities, serum FFA levels and on the increse of serum triglyceride levels and serum glucose levels. According to the results, both Hwangkikunjoohgtang and GamiHwangkikunjoong-tang showed remarkable effects in the recovery of exercise induced fatigue, but GamiHwangkikunjoongtang was more effective than Hwangkikunjoongtang.

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The Study on Concentration of Serum Copper and Zinc in Stomach Cancer Patients (위암 환자의 혈청내 구리 및 아연 농도에 관한 연구)

  • 정유덕
    • Journal of Nutrition and Health
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    • v.24 no.6
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    • pp.516-525
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    • 1991
  • In order to investigate whether serum Cu, Zn and Cu/Zn ratio are the useful indicater for the diagnosis of cancer. serum Cu and Zn levels were determined from 35 normal subjects and 33 stomach cancer patients by Atomic absorption spectrophotometer. The following results are obtained : Serum copper levels of stomach cancer patients were significantly increased than the those of the normal controls. whereas serum Zn levels significantly decreased than those of the normal contros(P<0.01) Therefore the copper to zinc ratio revealed a significant in the serum Cu and Zn levels. The serum protein and albumin levels were significantly lower in cancer patients(P<0.01) And the correlation analysis indicated that there was no significant correlation between serum Cu/Zn ratio and protein or albumin. These data suggest that the serum Cu. Zn and Cu/Zn ratio may be used as a diagnostic test in stomach cancer patients.

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Mineral Intakes and Serum Mineral Concentrations of the Pregnant and Lactating Women (임신$\cdot$수유부의 무기질 섭취와 혈청 무기질 함량에 관한 연구)

  • Kim Wooo Ju;Ahn Hong Seok;Chung Eun Jung
    • Korean Journal of Community Nutrition
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    • v.10 no.1
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    • pp.59-69
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    • 2005
  • The purpose of this study was to estimate the mineral intakes and serum mineral levels of pregnant and lactating women. The subjects consisted of 34 non-pregnant, 56 pregnant and 20 lactating women. Nutrients intakes were investigated by the 24-hr recall method, and serum major and trace minerals were analyzed by the ICP-spectrometry. Calcium (Ca) and zinc (Zn) intakes were observed lower than RDA especially for both pregnant and lactating women. Iron (Fe) intake of pregnant women was $85 - 139\%$ RDA through Fe supplementation, and that of lactating women was lower than RDA. Compared with non-pregnant women, the pregnant women had similar Ca intake and higher magnesium (Mg) intake. Comparing with the non-pregnant women, serum Ca level in pregnancy was lower, and that of lactating women was not significantly different. Serum phosphorus and Mg levels were not significantly different among the groups. Serum Fe level of pregnant and lactating women was lower than that of the non-pregnant women. Serum Zn level of pregnant women was lower than those in the lactating and non-pregnant women. Serum copper level decreased as the pregnancy progressed. Serum sodium (Na) level was higher in 2nd- and 3rd trimester and potassium (K) level was higher in 3rd trimester and lactating period than other groups. Na/K ratio was not significantly different among the groups. During all periods, there was no correlation between dietary intakes and serum levels in each minerals. Serum Ca level positively corrleated with serum Mg level, especially in 3rd trimester and lactating women. In general, serum mineral levels in pregnancy were changed compared to the levels in non-pregnancy and restored in lactation to the levels for non-pregnancy.

Effects of Taraxaci Herba on the Sex Hormon Changes and Lipid Metabolism in the Ovariectomized Rats (포공영이 난소적출 흰쥐의 성호르몬 변화 및 지질대사에 미치는 영향)

  • Kim, Ji-Eun;Yang, Seung-Jeong;Cho, Seong-Hee;Park, Kyung-Mi
    • The Journal of Korean Obstetrics and Gynecology
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    • v.28 no.1
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    • pp.1-12
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    • 2015
  • Objectives: Taraxaci Herba (TH) have been used in oriental medicine for many centuries as a heat-clearing, detoxifying and stimulating milk secretion drug. Therefore, the purpose of this study was to investigate the effects of TH on the sex hormone changes and lipid metabolism in the experimental model. Methods: The experimental model of menopause was induced by bilateral ovariectomy in rats. We used TH extract with freeze-dried and $200{\pm}20g$ female Sprague-dawley rats for this Study. The level of serum total cholesterol, serum triglyceride, serum HDL-cholesterol, serum total estrogen, serum progesterone, serum follicle stimulating hormone (FSH), and body weight were measured. Results: The results of this study were obtained as follows; 1. Sample A and Sample B significantly decreased body weight and level of serum total cholesterol, and significantly increased level of serum total estrogen as compared with control group. 2. Sample A decreased level of serum triglyceride, and was increased level of HDL-cholesterol, serum progesterone, serum FSH as compared with control group. 3. Sample B significantly increased level of HDL-cholesterol, serum FSH as compared with control group. 4. Sample B decreased level of serum triglyceride, and was increased level of serum progesterone as compared with control group. Conclusions: These results suggest that TH could be applied effectively on the treatment of menopausal syndrome.

Preoperative and Postoperative Anemia in Patients with Gastric Cancer (위암환자의 위절제술 전후의 빈혈)

  • Sohn, Jun-Ho;Yu, Wan-Sik
    • Journal of Gastric Cancer
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    • v.5 no.3
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    • pp.146-151
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    • 2005
  • Purpose: We have preoperatively and postoperatively investigated the characteristics of anemia in patients with gastric cancer in order to provide optimal medical care for the patients. Materials and Methods: Preoperative hemoglobin, serum iron, serum ferritin, serum vitamin $B_{12}$, and serum folic acid were measured for 321 patients with gastric cancer. These were measured again for 287 patients 6 months postoperatively. Results: Ninety-four patients (29.3%) had preoperative anemia. Preoperative hemoglobin, serum iron, and serum vitamin $B_{12}$ levels were higher in the patients with early gastric cancer than in patients with advanced gastric cancer. Preoperative hemoglobin, serum iron, and serum ferritin levels were higher in male patients than in female patients. The patients who had preoperative anemia showed a high probability of having postoperative anemia (P<0.001), and the patients who had low serum ferritin levels preoperatively showed a high probability of having low serum ferritin levels and iron deficiency anemia postoperatively (P<0.004). Conclusion: Preoperative ferritin deficiency should be improved by iron supplement, even though the patient may not be anemic at that time. Periodic postoperative measurements of the hemoglobin, serum iron, serum ferritin, serum vitamin $B_{12}$, and serum folic acid levels are highly recommended because postgastrectomy anemia is not rare. Finally, if any low hemoglobin, serum iron, serum ferritin, serum vitamin $B_{12}$, or serum folic acid levels are found, they should be treated in an appropriate way.

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The Significance of Serum Thyroid Peroxidase as a New Tumor Marker in Papillary Thyroid Carcinoma after Thyroidectomy (유두상 갑상선암의 수술후 재발예측인자로서 혈청 Thyroid Peroxidase의 의의)

  • Chang Hang-Seok;Na Jae-Wung;Chung Woong-Youn;Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.15 no.1
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    • pp.46-51
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    • 1999
  • Background: Total thyroidectomy and postoperative radiodiodine ablation therapy in differentiated thyroid carcinomas enhance the reliability of serum thyroglobulin(Tg) levels and radioiodine scan in detecting recurrence or distant metastasis. There have been, however, some limitations in using these methods under certain conditions. Recently, several reports have indicated that thyroid peroxidase(TPO) could be used as an alternative tumor marker. We aimed to estimate the significance of serum TPO levels in differentiated thyroid carcinoma. Materials and Methods: Forty-eight patients who had undergone total thyroidectomy due to papillary thyroid carcinomas and who had been followed-up for at least 3 years were classified into two groups: 27 patients without any evidence of recurrence in group 1; and 20 patients with recurrence or distant metastasis in group 2. All patients were examined by radioiodine scans. Serum Tg, TSH, antithyroglobulin antibody, and TPO were measured and the relationships were statistically analyzed. The sensitivity and specificity of $^{131}I$ scan, serum Tg, and serum TPO were evaluated. Results: Serum Tg levels were $3.81{\pm}5.16ng/mL$ in group 1 and $147.02{\pm}193.75ng/mL$ in group 2. Only 2 patients in group 1 showed Tg levels exceeding 10ng/mL. In contrast, 4 patients in group 2 were under 10ng/mL. Serum antithyroglobulin antibody and TSH levels showed no statistical difference between the two groups. In group 1, 16 patients showed negative serum TPO results, and 4 patients in group 2 showed negative results. There was no correlation among serum Tg levels, antithyroglobulin antibody titers, and serum TPO levels in each group. In group 2, 4 patients with negative serum Tg levels showed positive TPO results and positive whole body scans. Two cases with false negative $^{131}I$ scans showed positive serum TPO and Tg results. In 4 cases showing false negative serum TPO levels, serum Tg levels and $^{131}I$ scans were positive. Conclusion: Serum Tg levels, radioiodine scans, and serum TPO levels can be clinically used as complementary methods in the diagnosis of recurrent or metastatic thyroid carcinomas. Serum TPO levels may be helpful when other methods fail to detect recurrences or distant metastasis in highly suspected patients.

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Nutirtional Status of Iron, Zinc and Copper of Preschool Children Residing in Low-Income Area of Seoul

  • Son, Sook-Mee;Park, Sung-Hee
    • Journal of Community Nutrition
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    • v.1 no.1
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    • pp.3-9
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    • 1999
  • This study was performed to investigate the biochemical status of iron, zinc and copper for 125 preschool children (Males : 69, Females : 56) residing in a low-income area of Seoul. The number of subjects aged, 3, 4, 5 and 6 were 19, 41, 41 and 24, respectively. The hemoglobin level of the children aged 3 was 11.8 g/dl and was lower thant hat of the other groups(p<0.05). Similar results were found for hematocrit and serum zinc. The percentage of children with an iron deficiency assessed by Hb(3-5) years : <11.0g/dl, 6 years: <11.5g/dl), Hct(3-6 years : 33%, 6 years : <35%), serum transferrin(<16%) and serum ferritin(<10ng/ml) were 4.3%, 9.5%, 8.2% and 17.7%, respectively. The mean serum zinc was 67.9$\mu\textrm{g}$/dl and urinary zinc was 0.1300mg/day. Low serum zinc (61.0$\mu\textrm{g}$/dl) occurred in 28.0% of the children. The mean serum copper was 110.5$\mu\textrm{g}$/dl and urinary copper was 0.0126mg/day. The prevalence of children with elevated serum copper($\geq$ 130$\mu\textrm{g}$/dl) was 54.8%, which was higher than 7.4%, the prevalence of low serum copper(<70$\mu\textrm{g}$/dl). Children with higher status, more weight, larger girth of chest, or larger midarm circumference showed higher values of Hb. The height and weight of children also showed a positive crrelation with serum zinc(P<0.001-P<0.05).

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