• Title/Summary/Keyword: Skin injury

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The Effect of LED Light Irradiation on Skin Injury Cure of Rat (LED 광원이 Rat의 피부 창상 치유에 미치는 영향)

  • Cheon, Min-Woo;Kim, Seong-Hwan;Park, Yong-Pil;Kim, Tae-Gon;Yu, Seong-Mi
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.20 no.12
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    • pp.1087-1092
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    • 2007
  • We developed the 4-channel Light Medical Therapy Apparatus for Skin Injury Cure using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity and reservation. In this paper, the designed device was used to find out how high brightness LED light affects the skin injury of SD-Rat(Sprague-Dawley Rat). In the experiment, $1\;cm^2$ wounds on the skin injury of SD-Rat(Sprague-Dawley Rat) were made. Light irradiation group and none light irradiation group divided, each group was irradiated one hour a day for 14 days. In result, compared with none light irradiation group, the lower incidence of inflammation and faster recovery was shown in light irradiation group.

Medical adhesive related skin injury after dental surgery

  • Kim, Tae-Heung;Lee, Jun-Sang;Ahn, Ji-Hye;Kim, Cheul-Hong;Yoon, Ji-Uk;Kim, Eun-Jung
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.18 no.5
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    • pp.305-308
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    • 2018
  • An 87-year-old woman was referred for the extraction of residual teeth and removal of tori prior to prosthetic treatment. After surgery under general anesthesia, the surgical tape was removed to detach the bispectral index sensor and the hair cover. After the surgical tape was removed, skin injury occurred on the left side of her face. After epidermis repositioning and ointment application, a dressing was placed over the injury. Her wound was found to have healed completely on follow-up examination. Medical adhesive related skin injury (MARSI) is a complication that can occur after surgery and subjects at the extremes of age with fragile skin are at a higher risk for such injuries. Careful assessment of the risk factors associated with MARSI is an absolute necessity.

The Effects of Simultaneous Hand Washing by Nurse and Child Before IV Injection (아동과 간호사의 손씻기 프로그램이 정맥주사와 관련한 아동의 불안, 동통과 피부손상에 미치는 효과)

  • Lee, Ae-Ran;Park, Min-Im;Lee, Hyo-Soon;Kim, So-Hyun;Park, Jin-Kyong;Kim, Ji-Soo
    • Child Health Nursing Research
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    • v.14 no.2
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    • pp.129-137
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    • 2008
  • Purpose: To examine the effects on skin injury, pain, and anxiety when nurses and children simultaneous wash their hands before IV injections. Method: A nonequivalent control group, non-synchronized design study was used with 61 children. For a month and a half, children in the experimental group(30) following hand-washing guidelines, washed their hands with nurses before IV insertion. Anxiety and pain were observed and recorded during IV insertion using the Anxiety Reaction Scale and FACES pain scale. After 48-72 hours on IV therapy with an arm-board, skin condition was checked by a research assistant according to guidelines for assessing skin injury developed by the researcher. t-test, ${\chi}^2$-test, Pearson correlation, and Kendall's tau b were used to analyze data with the SPSS program. Results: Children who washed their hands with the nurse before IV insertion showed less pain (p =.021) and skin injury (p <.001) compared to the control group. Conclusion: This finding suggests that simultaneous hand washing by nurse and child before IV injection has a strong effect on skin injury caused by arm-boards used to maintain IV therapy as well as on pain during IV insertion. This program demonstrates an effective intervention to prevent skin injuries in children on IV therapy.

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Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature

  • Depa, Jayaramakrishna;Coritsidis, George
    • Journal of Trauma and Injury
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    • v.32 no.2
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    • pp.111-114
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    • 2019
  • Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.

Healing Effect of 635 nm Laser Diode in Skin Injury (635nm 레이저다이오드의 피부 결손 치유 효과)

  • Cheon, Min-Woo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.21 no.7
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    • pp.674-678
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    • 2008
  • Low level laser therapy has various therapy effects. This paper performed the basic study for fabricating the low level laser therapy apparatus, and one of the goals of this paper was to make this apparatus used handily. The apparatus has been fabricated using the laser diode and microprocessor unit. The apparatus used a 635 nm laser diode for laser medical therapy and was designed for a pulse width modulation type to increase stimulation effects. In this study, the designed device was used to find out how 635 nm laser diode affected the skin injury of SD-Rat(Sprague-Dawley Rat). We divided the participants into two groups; irradiation group which was irradiated 10 minutes a day for 9 consecutive days, and none irradiation group. The results showed that the study group had lower incidence of inflammation and faster recovery, compared with the control group.

The Effects of Balneotherapy in Alkaline Reduced Spring Water on Skin Injury Induced by UV Irradiation in Hairless Mice (자외선으로 손상된 무모생쥐의 피부에 알칼리환원온천수의 침수치료효과)

  • Yoon, Yang-Suk;Kim, Dong-Heui;Jin, Dan;Park, Mi-Soon;Chang, Byung-Soo;Lee, Jee-Yeon;Lee, Kyu-Jae
    • Applied Microscopy
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    • v.41 no.1
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    • pp.21-29
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    • 2011
  • Balneotherapy has been widely used for the treatment of skin diseases in the world. The purpose of this study was to determine the bath effect of the alkaline reduced spring water with the properties of high pH and low oxidation reduction potential (ORP) on the skin injury induced by ultra violet (UV) irradiation. For this purpose, hairless mice were irradiated with UV-B to cause skin injury, and individually taken a bath in spring water (experimental group) and tap water (control group) once a day for 40 min during 21 days. We observed histological changes of the back skin through macro- and microscopic methods compared to the control group. We found that skin injury of the experimental group was more quickly recovered than that of the control group. Under the light microscope, the experimental group showed that epidermal thickening (p<0.01) and the mast cell activation (p<0.001) were lower compared with the control group, in addition infiltration of inflammatory cells and degranulation of mast cells were less observed. These results suggest that regular bath in the spring water with the properties of high pH and low ORP has a positive effect on the skin injury induced by UV irradiation.

Effect of Ore Minerals on the Healing of Full-Thickness Skin Injury Model of Rat (광물성 미네랄이 흰쥐 전층 피부창상 치유에 미치는 효과)

  • Choi, Kwang-Man;Lee, Chang-Won;Lee, Mi-Young
    • Journal of Environmental Science International
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    • v.17 no.7
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    • pp.809-816
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    • 2008
  • The oriental ore minerals, which mainly consisted of talc, actinolite, sericite, and halloysite were developed, and then used to examine the healing effect on the skin wound in rats. Full-thickness square wounds were formed on the backs of rats after the hairs on the dorsal surface were shaved. The ore minerals were applied to examine the healing effect from day 0 to 15 after wounding. Notable wound healings in terms of congestion around the wound, wound contraction and epithelialization were found in ore mineral-treated groups. Moreover, microscopic results revealed the formation of epithelial layer, hair follicles and progressive angiogenesis in ore mineral-treated groups, while complete epithelial layer could not be found in the control. These results suggest that ore minerals from Korean indigenous ores may have wound healing effect on the skin injury in rats.

Development of an easy-to-handle murine model for the characterization of radiation-induced gross and molecular changes in skin

  • Chang, Hsien Pin;Cho, Jae Ho;Lee, Won Jai;Roh, Hyun;Lee, Dong Won
    • Archives of Plastic Surgery
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    • v.45 no.5
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    • pp.403-410
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    • 2018
  • Background Radiation-induced skin injury is a dose-limiting complication of radiotherapy. To investigate this problem and to develop a framework for making decisions on treatment and dose prescription, a murine model of radiation-induced skin injury was developed. Methods The dorsal skin of the mice was isolated, and irradiation was applied at single doses of 15, 30, and 50 Gy. The mice were followed for 12 weeks with serial photography and laser Doppler analysis. Sequential skin biopsy samples were obtained and subjected to a histological analysis, immunostaining against transforming growth factor beta (TGF-${\beta}$), and Western blotting with Wnt-3 and ${\beta}$-catenin. Increases in the levels of TGF-${\beta}$, Wnt, and ${\beta}$-catenin were detected after irradiation. Results All tested radiation doses caused progressive dermal thickening and fibrosis. The cause of this process, however, may not be radiation alone, as the natural course of wound healing may elicit a similar response. The latent appearance of molecular and histological markers that induce fibrosis in the 15 Gy group without causing apparent gross skin injuries indicates that 15 Gy is an appropriate dose for characterizing the effects of chronic irradiation alone. Thus, this model best mimics the patterns of injury that occur in human subjects. Conclusions This animal model can be used to elucidate the gross and molecular changes that occur in radiation-induced skin injury and provides an effective platform for studying this adverse effect without complicating the process of wound healing.

Nausea/Vomiting and Self-care in Patients with Cancer on Chemotherapy (항암화학요법환자의 오심.구토 및 자가간호 실태)

  • Kim Hye-Jin;Kim Hee-Seung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.12 no.2
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    • pp.180-185
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    • 2005
  • Purpose: The purpose of this study was to investigate the incidence and self care practice for nausea/vomiting in patients with cancer during chemotherapy. Method: The participants were 100 patients with cancer over 20 years of age who visited the outpatient department or were hospitalized for chemotherapy Self care in the case of nausea and vomiting was measured by the Dodd's scale. Data were analyzed using the SAS program and the following statistics were used frequency, percentage, unpaired t test, and Pearson correlation coefficient. Results: The ratio of the occurrence of nausea/ vomiting in the participants was 70.0%. The incidence of nausea/ vomiting was significantly higher for women than for men. The incidence of nausea/ vomiting was also higher for patients with cancer not in the gastro-intestinal system (GIS) compared to that for patients with GIS cancer. The incidence of nausea/ vomiting positively correlated with anorexia, skin injury, and fatigue. Conclusion: The ratio of occurrence of nausea/ vomiting for the participants was 70.0%. The incidence of nausea/ vomiting was higher fur women and patients with cancer not in the GIS. The incidence of nausea/ vomiting positively correlated with anorexia, skin injury, and fatigue. The results indicate that nausea/vomiting is a frequent symptom, particularly in women and there is a need to provide interventions to decrease the effects of this symptom.

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Toll-like Receptor 5 Agonism Protects Mice from Radiation Pneumonitis and Pulmonary Fibrosis

  • Wang, Zhi-Dong;Qiao, Yu-Lei;Tian, Xi-Feng;Zhang, Xue-Qing;Zhou, Shi-Xiang;Liu, Hai-Xiang;Chen, Ying
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4763-4767
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    • 2012
  • Radiation pneumonitis and pulmonary fibrosis are the main complications with radiotherapy for thoracic neoplasms, directly limiting the efficient dose in clinical application and currently there are few medicines that effectively function as radioprotectants. However, a TLR5 agonist, CBLB502, was confirmed to have protective efficacy against hematopoietic and gastrointestinal radiation syndromes in mice and primates. This study points to a new direction for protection against thoracic radiation-induced pulmonary syndromes and skin injury by CBLB502. We utilized the TUNEL assay, pathological analysis and immunohistochemistry to obtain evidence thatCBLB502 could alleviate the occurrence of radiation pneumonitis and pulmonary fibrosis as well as radiation-induced skin injury. It may thus play a promising role in facilitating clinical radiotherapy of thoracic neoplasms.