• Title, Summary, Keyword: Treadmill exercise

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The Effects of Treadmill Exercise on Blood components, Antioxidant enzymes and Reactive Oxygen in Hyperlipidemic Rats (트레드밀 운동이 고지혈증 흰쥐의 혈액 성분과 항산화효소 및 활성산소에 미치는 영향)

  • Jung, Byeong-Ok;Jang, Sang-Hun;Bang, Hyun-Soo
    • Journal of the Korean Society of Physical Medicine
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    • v.8 no.1
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    • pp.71-78
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    • 2013
  • PURPOSE: The purpose of this study was to investigate the effects of treadmill exercise on blood components and antioxidant system in hyperlipidemic rats. METHODS: Three weeks old male rats were randomly assigned into General diet(GD, n=10), High fat Diet(HD, n=10), and High fat diet+Treadmill exercise(HDT, n=10) groups. Treadmill exercise consisted of the treadmill running 5 times per week during 6 weeks(30 min/time for first 3 weeks and 60 min/time the other 3 weeks). RESULTS: The levels of triglyceride and total cholesterol were increased in HD group compared with GD group, and recovered to level of GD group by treadmill exercise(p<.05). Plasma glucose and insulin concentrations were increased in HD group compared with GD group, and recovered to level of GD group by treadmill exercise(p<.05). Glutathione(GSH) and glutathione reductase(GRD) concentrations were decreased in HD group compared with GD group, and these decreases returned to the level of GD group by treadmill exercise(p<.05). Xanthine oxidase(XO) and malondialdehyyde (MDA) concentrations were increased in HD group compared with GD group, and these increases retuned to the level of GD group by treadmill exercise(p<.05). CONCLUSION: This study showed that treadmill exercise application were effective treatment strategy on hyperlipidemia. Therefore, it could be considered as a treatment method in the patients with hyperlipidemia disease. Treadmill exercise, Hyperlipidemia, Blood components.

The Short Period Effects of Treadmill Exercise on Glucose Levels in SD Rats (트레드밀 운동이 SD계 흰 쥐의 혈당수준에 미치는 단기간의 효과)

  • Kim, Dong-Dae;Kwon, Won-An
    • Journal of Korean Physical Therapy Science
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    • v.17 no.3_4
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    • pp.23-28
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    • 2010
  • Purpose: Hyperglycemia is associated with an risk of cardiovascular disease, mortality, diabetes mellitus and musculoskeletal disorders. The purpose of this study was to analyse the effect of two different treadmill exercise on blood levels of glucose in SD rats. Methods: The experimental groups were divided into 2 groups. The exercise was performed in the treadmill for 20minutes with 15m/min(group I, n=20) and 25m/min(group II, n=20) Blood samples were collected before exercise, 6day and 12days after treadmill exercise. Results: A significant difference was only at 12days on independent samples t-test for both groups. There were statistically significant difference between pre and 6days, 6days and 12days, pre and 12days on tests of pairwise comparisons for each groups. Both group were showed linear effects following treadmill exercise in 12days. Conclusion: These results suggest that a trend toward decrease in the levels of glucose, following treadmill exercise, were revealed in both group. Aerobic exercise related to a positive effect in control of glucose level.

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The Exercise Capacity and Cardiovascular Factors in Patients with Exaggerated Blood Pressure Response during Treadmill Exercise Testing

  • Bae, Hyung-Joon;Shin, Kyung A
    • Korean Journal of Clinical Laboratory Science
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    • v.43 no.4
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    • pp.138-144
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    • 2011
  • Exaggerated blood pressure response during exercise has been found to increase the risk of future hypertension, left ventricular hypertrophy, cerebrovascular stroke, and CVD (cardiovascular disease) death. The aim of this study was to evaluate exercise capacity, cardiovascular factors in exaggerated blood pressure response during treadmill exercise testing. For research subjects, 72 subjects (normal blood response: 49 subjects, exaggerated blood response: 23 subjects) who received treadmill exercise test at J General Hospital were selected in this study. Exaggerated SBP (systolic blood pressure) response was defined as an SBP of 210 mmHg or greater during a maximal treadmill exercise test. The group with an exaggerated SBP response showed significantly higher values for RPP (rate pressure product) compared with the group with a normal SBP response. Subjects with METs (metabolic equivalents) had lower exaggerated SBP response than normal SBP response group. Subjects with recovery SBP had delayed exaggerated SBP response than normal SBP response group. Exaggerated SBP response to exercise is negative correlation with METs.

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Cytochemical Study on the Cytochrome Oxidase Activity and Myocardial Adaptation to Treadmill Exercise in Rat (흰쥐에서 Treadmill 훈련에 따른 심근의 적응과 cytochrome oxidase 활성에 관한 세포화학적 연구)

  • Choi, Jeung-Mok;Lee, Choong-Sik
    • Applied Microscopy
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    • v.31 no.1
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    • pp.59-70
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    • 2001
  • The present study was to elucidate the cytochemical study on the cytochrome oxidase (CO) activity and myocardial adaptation to treadmill exercise in rat. The three month Sprague-Dowley male $(150{\pm}10g)$ were used in experimental animal. The experimental groups were divided into 2 groups: the normal sedentary group and the treadmill exercise group. On each 1st and 3rd day, 1st, 4th, 8th, and 12th experimental week four rats of each group were sacrificed for tests. The morphometrical measurements were used to evalute the change of heart weight, rate of myocardial fibers to capillaries, and cytochemical study of CO activities, using light and electron microscopy. The results were as follows: The heart weights were more increased in the treadmill exercise group than those of their sedentary group. The rate of myocardial fibers to capillaries were not changed in sedentary group, but those were significantly from 4th weeks in the treadmill exercise group. The CO activity was not changed in sedentary group, but increased in treadmill exercise group after 1 st week. I and III types of CO activity were increased In sedentary group, in contast to II and III types in treadmill exercise group on electron micrographic study. These results suggest that, the treadmill exercise-induced changes in CO activity and rate of myocardial fibers to capillaries appear to be related to exercise, and the adaptive response seems to occurs from 4th week of treadmill exercise.

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The Effects of Fatigue Induced by Submaximal Treadmill Exercise on Body Sway (최대하 트레드밀 운동에 의한 피로가 신체 동요에 미치는 영향)

  • Lee, Mi-Sun;Yi, Chung-Hwi;Cho, Sang-Hyun;Kwon, Oh-Yun
    • Physical Therapy Korea
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    • v.7 no.2
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    • pp.35-54
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    • 2000
  • The purposes of this study were to assess variation of body sway prior to and after submaximal treadmill exercise; to determine the time course of the effects of a fatiguing performed on a treadmill on body sway; and to compare position sense prior to and after exercise in order to assess any variance in proprioception caused by submaximal treadmill exercise. The subjects were twenty-four healthy men in their twenties. They stood barefoot on the Kinesthetic Ability Training Balance Platform to measure body sway. Control trials were performed with eyes alternately open and closed. In the eyes open condition, they were asked to look at a target placed at eye level 1 m in front them. A total of 10 trials, each lasting 20 seconds, were performed. After this series of trials, position sense was measured. Subjects then exercised on the treadmill until 85% of each person's maximal heart rate was reached. The first series of postural sway measurements began immediately after this exercise. The second identical series of postural sway trials was performed at approximately 10 minutes after exercise. The third series was performed approximately 20 minutes after exercise. This allowed approximately 5 minutes of rest between each experimental series. Position sense was measured at approximately 15 and 25 minutes after exercise. The results were as follows: 1) There was a significant increase in body sway after submaximal treadmill exercise compared to pre-exercise values under both visual conditions (p<.05). 2) After submaximal treadmill exercise, under the eyes open condition, the mean value of body sway was significantly increased after both the first and second series (p<.05). Under the eyes closed condition, the mean value of body sway increased significantly after the first series but decreased significantly after the third series (p<.05). 3) Position sense, measured repeatedly after submaximal treadmill exercise, did not change significantly with respect to pre-exercise values (p>.05). These results suggest that fatigue induced by submaximal treadmill exercise produced an increase in body sway in young healthy subjects with or without visual input, but the increase appeared to be lasting less than 15 minutes. No significant change in position sense suggested that proprioception was unaffected by submaximal treadmill exercise-induced fatigue.

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Biomechanical Effectiveness of the Low-Dye Taping on Peak Plantar Pressure During Treadmill Walking Exercise in Subjects With Flexible Flatfoot

  • Lim, One-Bin;Kim, Jeong-Ah;Kwon, Oh-Yun;Yi, Chung-Hwi
    • Physical Therapy Korea
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    • v.22 no.2
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    • pp.41-51
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    • 2015
  • The purposes of this study were 1) to determine the effects of low-dye taping on peak plantar pressure following treadmill walking exercise, 2) to determine whether the biomechanical effectiveness of low-dye taping in peak plantar pressure was still maintained following removal of the tape during treadmill walking, and 3) to determine the trend towards a medial-to-lateral shift in peak plantar pressure in the midfoot region before and after application of low-dye taping. Twenty subjects with flexible flatfoot were recruited using a navicular drop test. The peak plantar pressure data were recorded during five treadmill walking sessions: (1) un-taped, (2) baseline-taped, (3) after a 10-minute treadmill walking exercise, (4) after a 20-minute treadmill walking exercise, and (5) after removal of the taping. The foot was divided into six parts during the data analysis. One-way repeated measures analysis of variance was performed to investigate peak plantar pressure variations in the six foot parts in the five sessions. This study resulted in significantly increased medial forefoot peak plantar pressure compared to the un-taped condition (p=.017, post 10-minute treadmill walking exercise) and (p=.021, post 20-minute treadmill walking exercise). The peak plantar pressure in the lateral forefoot showed that there was a significant decrease after sessions of baseline-taped (p=.006) and 10-minute of treadmill walking exercise (p=.46) compared to the un-taped condition. The tape removal values were similar to the un-taped values in the five sessions. Thus, the findings of the current study may be helpful when researchers and clinicians estimate single taping effects or consider how frequently taping should be replaced for therapeutic purposes. Further studies are required to investigate the evidence in support of biomechanical effectiveness of low-dye taping in the midfoot region.

Effects of Treadmill Exercise on Pulmonary Function and Gait Capacity in Stroke Patients : A meta-analysis (트레드밀 운동이 뇌졸중 환자의 폐기능과 보행능력에 미치는 효과 : 메타분석)

  • Cho, Sunghyoun;Choi, Kibok
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.2
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    • pp.169-185
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    • 2020
  • Purpose : This study aimed to conduct a comprehensive meta-analysis to evaluate the effect size for pulmonary function and gait capacity of treadmill exercise in stroke patients. In addition, we aimed to examine the current status of treadmill interventions and compare the effect sizes of treadmill training to provide evidence-based practice for future development and application. Methods : The meta-analysis study was conducted using research articles that applied treadmill exercise to stroke patients and were published between January 2005 and February 2020. For a systematic meta-analysis, we conducted a search using the PICOS framework and selected 25 domestic stroke- and treadmill-related studies. The Comprehensive Meta-Analysis program was used to calculate the effect sizes for lung function and gait capacity (6-minute walk test and 10 m walk test). As Cohen's d has a tendency to overestimate the effect size, we used Hedge's g to increase the accuracy in computing the effect size. Results : Based on the results of the meta-analysis, the total effect size of treadmill exercise was 0.535, which was statistically significant, with a medium effect size (p<0.05). The effects of treadmill exercise in stroke patients were divided into dependent variables, namely pulmonary function (0.372) and gait capacity (0.584). In addition, for gait capacity, the effect sizes were evaluated for both the 6-minute walk test (0.756) and the 10 m walk test (0.514). Conclusion : This study provides objective evidence of the effectiveness of treadmill-based gait training programs. We hope that the results of this study will help support the development and implementation of treadmill-based gait training in stroke patients. Treadmill training is expected to improve not only pulmonary function, but also the gait capacity of stroke patients. Long-term investigations on the effects of treadmill training in stroke patients are necessary.

The effects of treadmill exercise and feeding Allium tuberosum Rottler on blood glucose level with Streptozocin-inducde diabetic rat (트레드밀 운동과 부추 식이가 Streptozotocin 유발 당뇨병 백서에서 항당뇨효과에 미치는 영향)

  • Kim Dong-Kil;Oh Myung-Hwa;Kim Gye-Yeop
    • The Journal of Korean Physical Therapy
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    • v.14 no.4
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    • pp.28-44
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    • 2002
  • The purpose of this study is to discuss and analyze the effect of blood glucose on treadmill exercise, functional food and their combined treatment protocol on diabetic rats. These group were divided treadmill exercise group(n:12), functional food feeding group(n:12), treadmill exercise with functional food feeding group(n:12) and control group. The following results were obtained from this study. 1. The blood glucose level was showed significantly different in several group, treadmill exercise with functional food feeding group are most significantly on other group. 2. The inhibitory rate of body weight was not significantly different on each group. 3. The amount of feeding was not significantly in several group. 4. The Islets size and Connective tissue proliferation was showed significantly different except control group, treadmill exercise with functional food feeding group are more significantly than other group. These results show that treadmill exercise with functional food feeding and their several protocols can retard the setreptozotocin-induced dibetic rat.

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Effects of Low and Moderate Intensity Treadmill Exercise on Functional Recovery and Histological Changes After Spinal Cord Injury in the Rats (척수손상 백서모델에서 저강도 및 중강도 트레드밀 운동이 운동기능회복 및 조직학적 변화에 미치는 영향)

  • Kim, Gi-Do;Kim, Gye-Yeop;Kim, Eun-Jung
    • Physical Therapy Korea
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    • v.16 no.2
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    • pp.41-49
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    • 2009
  • This study was designed to investigate the effects of treadmill exercise of low-intensity and moderate- intensity on the functional recovery and histological change in spinal cord injury (SCI) rats. SCI was induced by the spinal cord impactor dropped after laminectomy. Experimental groups were divided into the Group I (normal control), Group II (non-treatment after SCI induction), Group III (low-intensity treadmill exercise after SCI induction), Group IV (moderate-intensity treadmill exercise after SCI induction). After operation, rats were tested at modified Tarlov scale at 2 days with divided into 4 groups, and motor behavior test (BBB locomotor rating scale, Grid walk test) was examined at 3, 7, 14, and 21 days. For the observation of damage change and size of the organized surface in spinal cord, histopathological studies were performed at 21 days by H & E, and BDNF(brain-derived neutrophic factor) & Trk-b immunohistochemistry studies were performed at 1, 3, 7, 14, 21 days. According to the results, treadmill exercise can play a role in facilitating recovery of locomotion following spinal cord injury. Specially, moderate-intensity treadmill exercise after SCI induction was most improvement in functional recovery and histological change.

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The Effects of Treadmill Exercise on Cognitive Performance, Brain Mitochondrial Aβ-42, Cytochrome c, SOD-1, 2 and Sirt-3 Protein Expression in Mutant (N141I) Presenilin-2 Transgenic Mice of Alzheimer's Disease (트레드밀 운동이 mutant (N141I) presenilin-2 유전자를 이식한 알츠하이머질환 모델 생쥐 뇌의 Aβ-42, cytochrome c, SOD-1, 2와 Sirt-3 단백질 발현에 미치는 영향)

  • Koo, Jung-Hoon;Eum, Hyun-Sub;Kang, Eun-Bum;Kwon, In-Su;Yeom, Dong-Cheol;An, Gil-Young;Oh, Yoo-Sung;Baik, Young-Soo;Cho, In-Ho;Cho, Joon-Yong
    • Journal of Life Science
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    • v.20 no.3
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    • pp.444-452
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    • 2010
  • The purpose of this study was to investigate the effects of treadmill exercise on $A{\beta}$-42, cytochrome c, SOD-1, 2 and Sirt-3 protein expressions in brain cytosol and mitochondria in mutant (N141I) presenilin-2 transgenic mice with Alzheimer's disease (AD). The mice were divided into four groups (Non-Tg-sedentary, n=5; Non-Tg treadmill exercise, n=5; Tg-sedentary, n=5; Tg treadmill exercise, n=5). To evaluate the neuroprotective effect of treadmill exercise, Non-Tg and Tg mice were subjected to exercise training on a treadmill for 12 wk, after which their brain cytosol and mitochondria were evaluated to determine whether any changes in the cognitive performance, $A{\beta}$-42 protein, cytochrome c protein, anti-oxidant enzymes (SOD-1, SOD-2) and Sirt-3 protein had occurred. The results indicated that treadmill exercise resulted in amelioration in cognitive deficits of Tg mice. In addition, the expressions of mitochondrial $A{\beta}$-42 and cytosolic cytochrome c protein were decreased in the brains of Tg mice after treadmill exercise, whereas antioxidant enzymes, SOD-l and SOD-2 were significantly increased in response to treadmill exercise. Furthermore, treadmill exercise significantly increased the expression of Sirt-3 protein in Non-Tg and Tg mice. Taken together, these results suggest that treadmill exercise is a simple behavioral intervention which can sufficiently improve cognitive performance and inhibit $A{\beta}$-induced oxidative stress in AD.