• Title, Summary, Keyword: Vitex rotundifolia

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Whitening Effects of Solvent Fractions Isolated from Vitex rotundifolia (만형자 용매 분획물의 미백 개선 효과)

  • Yu, Jae-Myo;Kim, Dong-Hee;Son, Jun-Ho
    • Journal of Applied Biological Chemistry
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    • v.58 no.3
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    • pp.266-271
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    • 2015
  • Recently many effort focused to understand the mechanical insights of melanogenesis to develop the agent for hyper-pigmentation. So this study was performed to investigate the depigmentation of Vitex rotundifolia. With B16F10 mouse melanoma cell, we have seen inhibition of the tyrosinase, MITF, TRP-1, TRP-2, and melanin synthesis, which eventually were dose dependently decreased by Vitex rotundifolia. Specially, Vitex rotundifolia decreased the protein levels of tyrosinase and TRP-1. In conclusion, Vitex rotundifolia showed the whitening activity in all the experiments mentioned above and we expect that it can be used for preventing melanin synthesis.

Secondary Metabolites Produced by Penicillium sp. JVF17 Isolated from Vitex rotundifolia (순비기나무(Vitex rotundifolia)로부터 유래한 Penicillium sp. JVF17가 생산하는 이차대사산물)

  • Bang, Sunghee;Shim, Sang Hee
    • Korean Journal of Pharmacognosy
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    • v.50 no.2
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    • pp.81-85
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    • 2019
  • An endophytic fungus, Penicillium sp. JVF17, was isolated from a leaf of Vitex rotundifolia in coastal area of Jeju island. Chemical investigation of this fungal strain resulted in the isolation of four compounds, piceol (1), cyclo (${\text\tiny{L}}-Pro-{\text\tiny{L}}-Val$) (2), isochromophilone VI (3), and dicitrinin A (4). Their chemical structures were elucidated by comparison of their spectral data such as NMR and ESIMS with reported literature values.

Effects of Vitex rotundifolia on radical scavenging and nitric oxide production

  • Choi, Jae-Ki;Cha, Dong-Seok;Lee, Yong-Jae;Ko, Sung-Hoon;Park, Ho-Jun;Lee, Se-Yeoun;Choi, Jae-Hyuk;Jeon, Hoon
    • Advances in Traditional Medicine
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    • v.10 no.2
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    • pp.51-58
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    • 2010
  • Vitex rotundifolia (V. rotundifolia) has been used for treating headache, dizziness, toothache and removal of fever as a traditional medicine in Korea. In the present study, we examined the antioxidant and anti-inflammatory activities of 85% methanol extract of V. rotundifolia. In various radical scavenging assays, V. rotundifolia exhibited strong scavenging effect on 1, 1-diphenyl-2-picrylhydrazyl free radical, superoxide radical, nitric oxide. To elucidate the anti-inflammatory properties of V. rotundifolia, we investigated the inhibition effects of nitric oxide production in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. V. rotundifolia suppressed nitric oxide production, iNOS and COX-2 expression dose-dependently through suppression of NF-$\hat{e}B$ activation without notable cytotoxicity. These findings mean that V. rotundifolia may be beneficial in oxidative stress-mediated inflammatory disorders.

Growth Environment and Morghological Characters of Vitex rotundifolia Communities in Pyonsanbando National Park (변산반도국립공원내 순비기나무군락의 생육환경 및 형태적 특성)

  • 김계환;박종민
    • Korean Journal of Environment and Ecology
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    • v.12 no.1
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    • pp.91-101
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    • 1998
  • Two large communities of Vicex rotundifolia were discovered for the first time at the beach of Pyonsanbando National Park. The growth environment and morphological characters of the communities were examined and analyzed to provide some basal data which would be helpful to establish measures for protection and to utilize the communities rationally. The results are as follows; The habitats of Vitex rotundifolia are located at Chakeundang beach of Kyokpo-ri and Kosapo beach of Woonsan-ni, Pyonsan-myon in Pyonsanbando National Park. The total area of this two communities was measured to be 2,755m$^{2}$ and 523m$^{2}$ of it was damaged. Two varieties, 49 species, 43 genera and 28 families as trees and shrubs were collected from inside of and the vicinal areas of the communities. Koelreuteria paniculata and Rosa rugosa were discovered and collected in these areas for the first time to be documented with the communities of Vitex rotundifolia. The largest individual of Vitex rotundifolia within the polulations reaches or 3.5cm in diameter at root collar and 6m in length of the runner on aboveground. The individuals of Vitex rotundifolia within the communities show good growth condition which the mean leaf length was measured to be 4.5cm, the mean leaf width 3.3cm, the mean leaf area 11.8cm$^{2}$ and the mean flower length 10.0cm. Vitex rotundifolia has been mostly recorded to be an evergreen shrub. But the present study discovered that it is rather deciduous.

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Cultivation Limit of Vitex rotundifolia, Tetragonia tetragonoides and Glehnia littoralis at Coastal Area and Physiological Vitality of RAW 264.7 cell and HL-60 cell (해안지대 순비기나무, 번행초, 갯방풍의 재배한계 및 RAW 264.7 세포와 HL-60세포의 생리활성)

  • Kim, Ji-Hoon;Park, Sun-Soon;Song, Chang-Khil
    • Korean Journal of Medicinal Crop Science
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    • v.16 no.1
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    • pp.44-50
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    • 2008
  • The cultivation boundary areas and biological activator efficacies of Vitex rotundifolia, Tetragonia tetragonoides and Glehnia littoralis were investigated. Investigation of coastal areas revealed the East and West cultivation boundary areas of Vitex rotundifolia and Gelhnia littoralis to be the Taean Peninsula, Taean-gun and Gangwon-do, Donghae-City. The East and West coastal cultivation boundary areas of Tetragonia tetrragonoides are Jeollanam-do and Kyeongsangbuk-do, Ulleung-gun. The natural habitat is less than 200 m from the coastal area. Most of the Vitex rotundifolia, Tetragonia tetragonoides and Glehnia littoralis grow naturally in a region of mixed sand, clay and loam, in direct sunlight. No dominant vegetation was located. To analyze anti-inflammatory efficacy, RAW 264.7 cells were used. Vitex rotundifolia, Tetragonia tetragonoides and Glehnia littoralis inhibited inflammation by 37%, 12% and 10% in $100{\mu}g/m{\ell}$, respectively. However, the anti-inflammatory efficacy of Glehnia littoralis was invalid. Analysis of anti-cancer activity was accomplished using HL-60 cells. Glehnia littoralis revealed 60% and 72% inhibition activity in $100{\mu}g/m{\ell},\;and\;200{\mu}g/m{\ell}$ respectively. No cytotoxicity inhibition activity was investigated in Vitex rotundifolia and Tetragonia tetragonoides.

Changes of the Coastal Sand Dune Vegetation after the Construction of an Embankment in Anmado

  • Ihm, Byung-Sun;Lee, Jeom-Sook;Kim, Ha-Song
    • The Korean Journal of Ecology
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    • v.26 no.3
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    • pp.103-108
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    • 2003
  • This study examined the coastal sand dune vegetation before and after the construction of an embankment on Anmado Island in order to compare vegetation in relation to the development of islands. A total of 24 species distributed on the sand dunes. 18 species were found to be in common before and after the construction of the embankment, which included Vitex rotundifolia, Imperata cylindrica var. koenigii, Zoysia sinica, etc. The species which were not found in this survey included Rumex japonicus, Setaria viridis, Portulaca oleracea, Artemisia japonica, Poiygonum aviculare, etc, and new species included Arena fatua, Carex boottiana, Lycium chinense, Leonurus sibiricus, Torilis japonica, Solanum carolinense, etc. The washing away of sand brought about the changes in habitat and the increase in naturalized plants, which included Oenothera odorata, Lepidium apetalum, Bidens bipinnata, Erigeron canadensis, Datura stramonium, Xanthium strumarium, Arena fatua, Solanum carolinense etc. In addition, the disturbance to this habitat led to the changes in vegetation. The main plant communities in the surveyed site were classified as Vitex rotundifolia-Imperata cylindrica var. koenigil community, Zoysia sinica-Calystegia soldanella community and Messerschmidia sibirica community. The sand dune vegetation on Anmado Island changed with regard to the community and the composition of species after the construction of the embankment, due to the sand being severely eroded. While Vitex rotundifolia community and Commelina communis community were found before the construction of the embankment, they were replaced by Vitex rotundifolia-Imperata cylindrica var. koenigii community, Zoysia sinica-Calystegia soldanella community and Messerschmidia sibirica community, after the construction of the embankment.

Application Analysis of Vitex rotundifolia by Difference of the Shallow-Extensive Green Roof System (저관리 옥상녹화의 식재기반 시스템 차이에 따른 순비기나무의 활용성 평가)

  • Park, Jun-Suk;Ju, Jin-Hee;Kim, Won-Tae;Yoon, Young-Han
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.13 no.4
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    • pp.10-17
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    • 2010
  • The objectives of this study were to compare the growth of Vitex rotundifolia as affected by the difference of soil depth and mixture ratio in a shallow-extensive green roof module system, and to identify the level of soil thickness and mixture ratio as suitable growing condition to achieve the desired plant growth in green roof. Different soil thickness levels were achieved under 7cm, 15cm and 25cm of shallow-extensive green roof module systems made by woody frame of $500{\times}500{\times}300mm$. Soil mixture ratio were eight types for perlite : peatmoss : leafmold = 7 : 1 : 2 (v/v/v, $P_7P_1L_2$), perlite : peatmoss : leafmold = 6 : 2 : 2 (v/v/v, $P_6P_2L_2$), perlite : peatmoss : leafmold = 5 : 3 : 2 (v/v/v, $P_5P_3L_2$), perlite : peatmoss : leafmold = 4 : 4 : 2 (v/v/v, $P_4P_4L_2$), only sand ($S_{10}$), sand : leafmold = 7 : 3 (v/v, $S_7L_3$), sand : leafmold = 5 : 5 (v/v, $S_5L_5$) and only leafmold ($L_{10}$). The growth response of Vitex rotundifolia had fine and sustain condition in $P_6P_2L_2$, $P_5P_3L_2$ and $P_4P_4L_2$., Especially, in case of $P_6P_2L_2$, growth response appeared to be good even in soil thickness 7cm, which showed low survival rates of Vitex rotundifolia in other soil mixtures. Tree height, root diameter, photosynthesis and chlorophyll contents tended to increase with increased soil thickness.

Chemical Investigation on an Endophytic fungus Gibberella moniliformis JS1055 Derived from a Halophyte Vitex rotundifolia

  • Kim, Jung Wha;Ryu, Jiyoung;Shim, Sang Hee
    • Natural Product Sciences
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    • v.24 no.3
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    • pp.189-193
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    • 2018
  • Chemical investigation of the ethyl acetate extract of Gibberella moniliformis JS1055 endophytic fungus derived from a halophyte, Vitex rotundifolia, led to the isolation of nine compounds including 7-butyl-6,8-dihydroxy-3(R)-pent-11-enylisochroman-1-one (1), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one (2), 7-butyl6,8-dihydroxy-3(R)-pentylisochroman-1-one (3), $5{\alpha},8{\alpha}$-epidioxyergosta-6,9(11),22-trien-3-ol (4), ergosterol peroxide (5), tetradecanoic acid (6), 8-O-methylfusarubin (7), nicotinic acid (8) and adenosine (9). They were identified by extensive spectroscopic data analysis including 1D, 2D ($^1H-^1H$ COSY, HSQC, HMBC) NMR, and ESIMS. All the isolates (1-9) are reported for the first time from this endophytic fungus.