• 제목, 요약, 키워드: butyltin

검색결과 44건 처리시간 0.032초

Butyltins in Surface Sediments of Kyeonggi Bay, Korea

  • Kim, Gi-Beum;Tanabe, Shinsuke;Koh, Chul-Hwan
    • Journal of the korean society of oceanography
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    • v.33 no.3
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    • pp.64-70
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    • 1998
  • Forty sediment samples from Kyeonggi Bay, Korea were analyzed for butyltins, including tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) to determine their distribution and source in this area. Total butyltin concentrations in Kyeonggi Bay sediments ranged from 0.8 to 297 ng/g dry wt. with a mean value of 38 ng/g. The highest butyltin concentration was found in the innermost site in Incheon Harbor basin. The mouth of Han River had higher butyltin levels in sediments compared to open ocean. Butyltin levels correlated well with organic carbon content of sediment, but the major factor was the distance from the source area where antifouling paints were used for vessels and marine structures. Butyltin concentrations in the study area were lower than those reported for bays in other parts of the world. Considering the high toxic potential and sediment/water partition coefficient of TBT, further studies are needed to assess its biological effect in the marine ecosystem of Kyeonggi Bay.

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In vitro 및 In vivo Assay를 통한 중금속의 에스트로겐성 평가 (Assessing Heavy Metals for Estrogenicity Using a Combination of In vitro and In vivo Assays)

  • 박철;김소정;신완철;김혜경;최석영
    • 한국식품영양과학회지
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    • v.33 no.9
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    • pp.1486-1491
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    • 2004
  • 식품오염 관련 중금속들의 에스트로겐성을 in vitro 와 in vivo 분석방법을 병행하여 평가하였다. 분석방법은 1) estrogen receptor dependent transcriptional expression 분석법, 2) E-screen assay 그리고, 3) 마우스 자궁비대시험 (uterotropic assay)을 사용하였다. 시험에 사용한 물질로는 $17\beta$-estradiol, diethylstilbestrol(DES), arsenic oxide, bis (tri-n-butyltin), cadmium chloride, chromium chloride, lead acetate, mercuric chloride을 사용하였다. Estrogen receptor dependent transcriptional expression 분석 결과, bis(tri-nbutyltin) > cadmium chloride > chromium chloride 순으로 에스트로겐성이 크게 나타났으며, mercuric chloride, lead acetate, arsenic oxide는 거의 나타나지 않았다. E-screen test 결과, bis(tri-n-butyltin) > cadmium chloride > chromium chloride 순으로 에스트로겐성이 크게 나타났으며, mercuric chloride, lead acetate, arsenic oxide는 거의 나타나지 않았다. 자궁비대시험 결과도 마찬가지로 bis(tri-nbutyltin), cadmium chloride, chromium chloride은 자궁중량 비대를 크게 초래하였으며, 반면에 mercuric chloride, lead acetate, arsenic oxide는 그러한 효과가 미약하거나 없었다. 세 분석방법 결과 bis(tri-n-butyltin), cadmium chloride, chromium chloride 순으로 에스트로겐성이 크게 나타났다. 이러한 결과는 최근 bis(tri-n-butyltin)과 cadmium chloride이 에스트로겐성이 있다는 다른 연구결과들과 잘 일치하며, 또한 크롬화합물도 에스트로겐성이 있다는 것을 새롭게 제시하고 있다. 본 연구는 세 단계 수준(전사활성화단계, 세포증식작용, in vivo assay)의 분석을 병행함으로써 수많은 중금속의 에스트로겐성을 효과적으로 평가할 수 있다는 것을 제시해주고 있다.

식품용 염화비닐수지제 기구 및 용기.포장 중 부틸주석화합물의 모니터링 - GC/MS를 이용한 염화비닐수지제 식품용 랩 및 가스킷 재질 중 부틸주석화합물 잔류량 분석 (Monitoring of Butyltin Compounds in PVC Food Packaging - Determination of Butyltin Compounds in PVC Wrap and Gasket for Food Packaging by GC/MS)

  • 성준현;윤혜정;최현철;전대훈;엄미옥;김형일;박나영;이은준;이영자
    • 한국식품과학회지
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    • v.39 no.6
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    • pp.715-720
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    • 2007
  • 국내 유통되는 PVC제 랩 3건 및 병마개 가스킷 26종에 대한 부틸주석화합물의 재질 중 잔류량을 조사하였다. Mono-n-butyltin(MBI), di-n-butyltin(DBT) 및 tri-n-nutyltin(TBT)에 대하여 sodium tetraethylborate로 ethylation 유도체화 후 GC/MS-SIM으로 분석하였다. 분석법 검증결과 본 연구에서 사용한 분석방법의 검출한계는 $0.005\;{\mu}g/mL$였으며, $0.02-3.13\;{\mu}g/mL$의 농도범위에서 $R^2$ 값이 0.999 이상의 직선성, 90% 이상의 회수율을 확인할 수 있었다. 총 29건의 시료에 대하여 분석한 결과 모든 시료에서 부틸주석 화합물은 검출되지 않았다.

혈액 중의 주석화합물(MBT, DBT, TBT)의 분석과 농도에 관한 연구 (Analysis of Butyltin Compounds(mono-, di-, and tributyltin) in Human Blood)

  • 김남숙;박동욱;오재룡;심원준
    • 분석과학
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    • v.14 no.2
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    • pp.115-122
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    • 2001
  • 우리나라 해안에 인접한 "K"지역 병원에서 구한 44명의 혈액에서 유기주석화합물인 mono-butyltin(MBT), dibutyltin(DBT) 그리고 tributyltin(TBT)을 불꽃광도검출기가 부착한 가스크로마토그라프로 분석하였다. 본 연구의 목적은 일부 주민의 혈액을 대상으로 MBT, DBT, TBT에 대한 분석방법과 농도를 고찰하는 것이다. 본 연구에서 이용한 분석방법에 대한 검출한계(method detection limit, MDL)는 MBT 3.67, DBT 0.91, TBT는 1.09ng Sn/g 습중량 기준으로 나타났다. 또한 일본 국립환경연구소가 제조한 농어중의 $1.3{\mu}g/g$ TBT as chloride의 농도가 가진 표준물질(standard reference material)을 분석한 결과 공인값과 잘 일치하였다. 혈액 중에서 검출된 농도의 범위는 MBT가 3.69-7.93ng Sn/g, DBT 1.15-5.41ng Sn/g이었고, TBT는 검출한계 미만 및 미검출이었다. 혈액중에서 검출된 MBT 및 DBT의 흡수와 축적은 사람들이 유기주석화합물이 생체축적된 수산물의 섭취, 각종 플라스틱류 사용 등에 원인이 있을 것으로 사료된다. 혈액중 유기주석화합물이 인체로 흡수되는 내재용량(internal dose)을 평가할 수 있는 지표서의 신뢰성에 관한 연구가 계속해서 진행되어야 할 것으로 판단된다.

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제주도 한림항내 표층퇴적물 중의 부틸주석화합물의 분포 (Distribution of Butyltin Compounds in Surface Sediments inside Hallim Harbor of Jeiu Island, Korea)

  • 감상규;김현정;허철구;최영찬;이민규
    • Journal of Environmental Science International
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    • v.12 no.7
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    • pp.753-762
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    • 2003
  • Butyltin compounds (BTs), namely tributyltin (TBT), dibutyltin (DBT) and monobutyltin (MBT), were measured in surface sediments collected in 2001 inside Hallim Harbor where a lot of shipping occurs as one of major harbors of Jeju Island, in order to evaluate their distribution. BTs were detected in surface sediments of all stations and their concentrations were comparable to those in surface sediments of other sites of domestic and foreign countries. The main species among BTs was MBT, although there was a little difference with a survey site. No correlations were obtained between organic matter or particles size of surface sediments and total BTs, indicating that these factors did not affect on the distribution of BTs. It was estimated that more complex factors including BTs loads and surrounding sedimentary environments, affected on the distribution of BTs. The high correlations between BTs indicated that DBT and MBT were mainly degraded from TBT based on antifouling paints of vessel etc. and other sources, such as DBT and MBT, could be ignored. The butyltin degradation indexes ([DBT] + [MBT]/[TBT]) Ivere in the range of 1.5∼3.3 (mean 2.5), indicating that the parent compound, TBT, were inflowed into the surface sediments a long years ago and degraded.

Occurrence of butyltin compounds in marine environment of Gwangyang Bay, Korea

  • Park, Hee-Gu;Kim, Sang-Soo;Moon, Hyo-Bang;Gu, Bon-Kyu
    • Journal of Environmental Science International
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    • v.11 no.8
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    • pp.793-800
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    • 2002
  • Butyltin (BT) compounds were measured in seawater, sediment, sediment core, settling solids, and plankton from Gwangyang Bay in 2001, Tributyltin (TBT) was detected in seawater from 1 out of the 7 seawater sampling sites and in sediment from 18 out of the 35 sediment sampling sites. The highest concentration of TBT was found in the sediment from the site near Yeosu Harbor (53 ng Sn/g dry wt), acting as the point source for TBT The mean concentrations of TBT were in the order of plankton> settling solids> sediment. The degradation indexes ([DBT]+[MBT]/[TBT]) for the plankton were less than 1, indicating the possibility of recent inputs of TBT. The indexes for the sediment and settling solids ranged from 1.14 to 8.73. The composition of the BT compounds found in the settling solids was similar to that found in the sediment. The vertical profile of the total BT compounds in the sediment was characterized by an abrupt decline from the surface. However, no butyltin compounds appeared below a depth of 10 cm, corresponding to the 1980s. Accordingly, the current results demonstrated that the levels of all butyltin species in the environment of Gwangyang Bay were relatively lower than those in other polluted coastal areas. The vertical profile also suggested a fairly recent history for the down-core.

Determination of Mono-, Di-, and Tri-Butyltin Compounds in Seawater of Several Bays in Korea

  • Choi, Hwa-Seon;Kwon, Ee-Yol;Lee, Dong-Sup
    • Bulletin of the Korean Chemical Society
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    • v.14 no.2
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    • pp.234-238
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    • 1993
  • The method of study describes the determination of the nanogram amounts of mono-, di-, and tri-butyltin compounds in sea water. The procedure is based on 1) the conversion of tin compounds to non-ionic species by sodium tetraethyl borate as an alkylation reagent, 2) one-step ethylation and 3) extraction. No further purification or concentration of the extract was required before GC-FPD (Flame Photometric Detector). The detection limits for mono-, di- and tri-butyltin were 12.50, 6.02, and 4.19 ng/L. The linear range (0-120 ng/L) was solely dependent on the detector response height. Sea water samples (n=24) were obtained from Masan Bay, Busan, Ullsan, Gunsan, Sockcho, Yeasu, Donghae, Inchun, Kanghwa, and Ahsan in Korea. The samples were collected between June, 1992 to July, 1992 and the distribution of monobutyltintrichloride (MBTC), dibutyltindichloride (DBTC), and tributyltinchloride (TBTC) in sea water was recorded. The concentrations of butyltin compounds in seawater were found to be in the range of N.D. (not detected)-61.93 ng/L for MBTC, N.D.-32.16 ng/L for DBTC, and N.D.-55.76 ng/L for TBTC.

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Butyltin Compounds Concentrations in Masan Bay

  • CHOI Hee Gu;KIM Pyoung Joong;LEE Won Chan
    • 한국수산과학회지
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    • v.30 no.6
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    • pp.923-928
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    • 1997
  • The occurrence of butyltin compounds in the seawater and sediment of Masan Bay was investigated. The concentrations were in the range of $ND-0.059{\mu}g/\ell$ for tributyltin (TBT), $ND-0.091{\mu}g/\ell$ for dibutyltin (DBT) and $ND-0.720{\mu}g/\ell$ for monobutyltin (MBT) in the seawater, and $ND-0.233{\mu}g\;TBT/g.dry$, $ND-0.197{\mu}g-DBT/g.dry$ and $ND-0.684{\mu}g-MBT/g.dry$ in the sediment. Among the butyltin compounds, the major component in the seawater was MBT, while the predominant species in the sediment changed with time. The tributyltin concentrations in the sediment are approximately three orders of magnitude greater than the associated water column levels. Sediment/water partition coefficients (K) of TBT were between $0.6\times10^3\;and\;5.0\times10^3$.

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제주도 제주항내 퇴적물 중의 부틸주석화합물의 오염 (Contamination of Butyltin Compounds in Sediments inside Jeju Harbor of Jeju Island)

  • 감상규;허철구;이민규
    • Journal of Environmental Science International
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    • v.20 no.5
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    • pp.655-665
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    • 2011
  • Contamination of butyltin compounds (BTs), namely tributyltin (TBT), dibutyltin (DBT) and monobutyltin (MBT), was evaluated in sediments collected inside Jeju Harbor in 2001. The concentrations of BTs in surface sediments were comparable to those in other sites of domestic and foreign countries. The high correlations between BTs in surface ($r^2$ = 0.83~0.91) and core ($r^2$ = 0.70~0.79) sediments and the significant correlations between BTs concentrations and the number of incoming and outgoing vessels indicated that DBT and MBT were mainly degraded from TBT based on antifouling paints of vessels etc. and other sources, such as DBT and MBT, could be ignored. The butyltin degradation indices ([DBT] + [MBT]/[TBT]) in surface sediments were in the range of 2.2~3.6 (mean 2.7), indicating that the parent compound, TBT, was inflowed into the surface sediments a long ago, degraded and deposited. The sedimentation age of BTs contaminated core sediments could not estimated because the content of $^{210}Pb$ activity was nearly all the same and so the sedimentation rate could not obtained.

Application of a Gas Chromatography/Mass Spectrometric Method for the Determination of Butyltin Compounds in Sediment

  • Won, Yong-Il;Jung, Pyong-Gil;Chung, Min-Young;Kim, Byung-Joo;Yim, Yong-Heon;So, Hun-Young;Kim, Yong-Seong
    • Bulletin of the Korean Chemical Society
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    • v.25 no.10
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    • pp.1508-1512
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    • 2004
  • A gas chromatography/mass spectrometric (GC/MS) method has been developed for the determination of trace mono-n-butyltin (MBT), di-n-butyltin (DBT), and tri-n-butyltin (TBT) compounds in sediments. Samples were extracted by 10% acetic acid in methanol containing 0.03% tropolone and were then derivatized for GC/MS analysis. Ethylation by sodium tetraethylborate and phenylation by sodium tetraphenylborate were evaluated as a derivatization reaction of the organotins in sample extract. n-Hexane was added into reaction media in the beginning of the reaction for the continuous extraction of derivatized organotins. Ethylation requires less than 2 hours to get proper derivatization yields for MBT, DBT, and TBT altogether and produces relatively low amounts of side reaction products. Compared to ethylation, phenylation requires much longer time but provides relatively lower yield and produces considerable amounts of side reaction products. Therefore, the ethylation reaction was applied for the analysis of organotin compounds in sediment. An isotope dilution mass spectrometric (IDMS) method based on GC/MS has been applied to the accurate determination of DBT compounds in the sediments. The IDMS results from the analyses of sediment samples showed a reasonable repeatability and a good agreement with the values obtained by IDMS based on liquid chromatography/induced coupled plasma/mass spectrometry.