• Title, Summary, Keyword: emulsion method

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Characterization of Emulsion Properties for Modified Amino Polysiloxanes (아미노 변성 폴리실록산의 유화 특성)

  • 하윤식;서무룡;이정경;박경일;장윤호
    • Journal of Environmental Science International
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    • v.8 no.1
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    • pp.61-67
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    • 1999
  • Silicone oil has organic and inorganic properties, and its skeleton is polysiloxane bonding that silicon is bonded hydrogen or organic group. Silicone compounds are very smooth and lubricant properties by low surface tension, low temperature dependence, and nonadhesive properties. Because of these properties, silicone compounds are used as many parts of chemicals, softener, smooth and libricant agents, water-repellent agent, and defoaming agent, etc. Emulsion was prepared with the inversion emulsification method which adopted the agent-in-oil method dissolving the polyoxyethylene(7) tridecyl ether(HLB 12.2) into methoxy terminated poly(dimethyl-co-methyl amino) siloxane and hydroxy terminated poly(dimethyl-co-methyl amino) siloxane in water. At this time, processed emulsion was almost microemulsion. When ratio of emulsifier increases, emulsion is stable bacuause microemulsion is solubilized by emulsion drop size and zeta-potential are decreased. But, when amount of electrolyte is increase, emulsion became unstable because emulsion drop size is increased.

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The Formulation of Semi-Transparent Gel Emulsion by the Liquid Crystal Emulsification Method

  • Kim, Jungil;Lee, Youngkeun;Kim, Yongmin;Yun, Seiyoung
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1478-1486
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    • 2018
  • Liquid crystals offer plenty of useful activities as improving the stability of emulsion, increasing moisturizing power, drug release, improving skin feeling and visual effect for cosmetics fields. In order to prepare stable semi-transparent gel emulsion, liquid crystal emulsification method was used. The emulsion stabilities of systems containing glycerin, fatty alcohols, surfactants, water and oil were investigated at various temperatures as time passed. The stabilities of all emulsions were evaluated by means of a polarizing microscope, SEM, rheometer, colorimeter and DSC. Even though the samples stored at $50^{\circ}C$ thermostatic chamber were occurred the reduction of hardness, turbidity and ${\Delta}H$ and the peak shift, the semi-transparent gel emulsion was very stable without separation between water and oils phase in emulsion.

Preparation and Antibacterial Effects of Scutellariae Radix Extract Emulsion Containing Baicalin (바이칼린을 함유한 황금 엑스 유제의 제조 및 항균효과)

  • Yang, Jae-Heon;Kim, Young-Il
    • Journal of Pharmaceutical Investigation
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    • v.28 no.3
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    • pp.159-164
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    • 1998
  • The O/W and W/O emulsions containing Scutellariae Radix extract(SRE) which is very slightly soluble in oil phases and sparingly soluble in water phases, were prepared by homogenizing water and oil phases with emulsifier. The diameters of emulsion were ranged from 100 to $300\;{\mu}m$. The viscosity of W/O emulsion was higher than that of O/W emulsion. W/O emulsion was more stable than O/W emulsion which was gradually degraded when tested by centrifuge method and temperature tolerance method at $50^{\circ}C$. The antibacterial activity of two emulsions was not significantly different from that of aqueous solution of SRE, and showed similar MIC and bacterial growth inhibition rate.

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The Stability of Emulsions Formed by Phase Inversion with Variation of HLB of Surfactant (HLB 변화와 전상유화에 의해 형성된 에멀젼의 안정성)

  • Park, Soo-Nam;Yang, Hee-Jung;Kim, Jae-Hyun;Cho, Wan-Goo
    • Journal of the Korean Applied Science and Technology
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    • v.26 no.2
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    • pp.117-123
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    • 2009
  • Caprylic/Capric triglyceride-in-water emulsions stabilized by Nikkol HCO-60 and HCO-10 were prepared using emulsion inversion point method at different HLB values. Emulsions with various droplet sizes were formed, and emulsion inversion point was detected by electrical conductivity. The change in emulsion droplet sizes and long term stability were monitored using laser scattering method and visual method. The droplet sizes and stability of emulsions were affected by HLB of surfactant. At emulsion inversion point, the water volume fraction increased as the HLB of surfactants decreased. According to our analysis, this resulted from a tendency of forming the W/O (water-in-oil) emulsion as the HLB of surfactants was decreased. The emulsion inversion point was clearly detected by the microscope and the electric conductivity meter. Nanometer-sized emulsion was obtained at the optimum HLB by using emulsion inversion point method. The main pattern of instability of emulsions in HLB 12 and 13 systems was Ostwald ripening. However, The patterns of instability of emulsions below 11 of HLB systems were Ostwald ripening and coalescence. All emulsions produced with surfactants in the range of HLB 8-13, creaming caused by density difference between water phase and oil phase.

The Effects of Ethanol on Nano-emulsions Containing Quercetin Prepared by Emulsion Inversion Point Method (에멀젼 반전법으로 제조된 쿼세틴을 함유하는 나노에멀젼에 대한 에탄올의 영향)

  • Park, Soo-Nam;Won, Bo-Ryoung;Kang, Myung-Kyu;Ahn, You-Jin
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.35 no.2
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    • pp.79-89
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    • 2009
  • The objective of this study was to find out the stable formulation of nano-emulsion containing high concentration of quercetin and to investigate the effect of an ethanol on the nano-emulsion prepared by POE (30) hydrogenated castor oil (HCO-30)/oil/quercetin/ethanol/water system. Nano-emulsion was prepared using emulsion inversion point (EIP) method as low-energy method plus homogenizer as high-energy method. To evaluate effect of ethanol and other components on the nano-emulsion, physical properties such as droplet size, morphology, and size distribution were determined. The optimal quercetin concentration was 0.2 % on the nano-emulsion. The droplet diameter was below 300 nm at the HCO-30 concentration below 2.00 %. Nano-emmulsion containing 4.75 % HCO-30 was the most stable and its mean droplet size was 172.40 nm. Finally, the size of nano-emulsion containing 4.00 % ethanol was 128.15 nm and size distribution was also narrow. The results showed that the breakdown process of this nano-emulsion could be attributed to Ostwald ripening. This study about effect of ethanol on the nano-emulsion showed that loading capacity of drug could be increased by using a small amount of ethanol. As prepared stable nano-emulsion, this study showed that these results could be applied to pharmaceutics, cosmetic including skin-care products, perfume and etc.

Recent Emulsion Technology in Cosmetics (화장품용 유화 제조기술 최근동향)

  • Hwang, So-Ra;Nam, Jin-Oh;Lee, Byung-Jin;Song, Woo-Ho;Lee, Chang-Soo
    • KSBB Journal
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    • v.27 no.4
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    • pp.207-214
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    • 2012
  • Emulsions are mixture of immiscible liquids in which one is dispersed in all over the other. They have been applied to many applications including cosmetics, foods, drug delivery system (DDS), fine chemicals, and chemical separations. Especially, emulsion technology is one of the most useful technique to formulate cosmetics such as eye cream, foundation, and foam cleansing. In general, the emulsions can be generated by mechanical agitation of two immiscible fluids. However, the emulsions obtained by conventional method have limited in stability, monodispersity, and complicate process. We describe here preparation techniques of representative cosmetic emulsions such as liposome, liquid crystal emulsion, nanoemulsion, multiple emulsion, and pickering emulsion. Furthermore, various factors which can control the physical properties of each cosmetic emulsions are briefly discussed.

Release Profile of Peptide from Biodegradable Microspheres: Comparison of Blending and Multiple Emulsion Method (고분자 혼합법과 다중 에멀젼법에 의해 제조된 생분해성 미립구로부터 펩타이드의 용출에 관한 연구)

  • Jung, Goo-Young;Kim, Jung-Kwoun;Park, Mork-Soon;Myung, Pyung-Keun
    • Journal of Pharmaceutical Investigation
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    • v.36 no.4
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    • pp.245-251
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    • 2006
  • The novel microsphere blending and multiple emulsion method by single process was tried to prepare sustained release microspheres which release a physiologically active substance for long periods of time. A drug was separately dissolved in each of two or more oils containing biodegradable polymers to give the primary oil phases. The primary oil phases were dispersed in single aqueous phase in succession. From the drug-dispersed solution, the organic solvent was removed to produce microspheres. The accelerated drug release from the microsphere formulation prepared by single process through the multiple emulsion method was very similar to a physical blending of separately prepared microspheres using the same polymers. But long term release was not same. In this study, leuprorelin acetate loaded poly(lactide-co-glycolide) microsphere formulation for one-month delivery was developed by the multi-emulsion method followed by solvent extraction/evaporation method.

A case study of large - long tunnel using the charging mechanization system of the bulk emulsion explosives (Bulk Emulsion 기계화 장전시스템을 이용한 대단면 장대터널 시공사례연구)

  • Yoon, Ji-Sun;Jang, Young-Min;Lee, Sang-Hun
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.11 no.2
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    • pp.107-115
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    • 2009
  • Lately, the length of tunnel, the number of large-long tunnel over three lanes are steeply increased because of the request for high speed and straight road. Therefore, the maximization of excavation efficiency is needed in tunnel construction. Bulk Emulsion explosives charging system is the spearhead equipment using the radio remote control $&$ mechanization system compare with a traditional method Cartridge type. This study introduced the bulk emulsion explosives which is new method in tunnel blasting and verified the efficiency of bulk emulsion explosives for long-large tunnel. And we tried to compare Cartridge type efficiency with bulk emulsion explosives efficiency by the field test.

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Determination of Emulsion Stability Index in W/O Emulsion (유중수적형 유화계내에서의 유화안정지수 산출법의 확립)

  • Chang, Pahn Shick
    • Analytical Science and Technology
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    • v.7 no.2
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    • pp.233-236
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    • 1994
  • To evaluate the emulsion stability indices of W/O emulsion system, we developed the simple and sensitive "VOLUMETRIC METHOD". This technique involved the first step of homogenizing the milk fat-water system with Ultra-turrax T25, then the volume of the added water phase was measured immediately. After quiescent incubation in test tubes at room temperature for a desired storage time, the bottom volume of the separated water layer was measured. And then "emulsion stability index(ESI)" was calculated by the following equation : $ESI=(1-V_s/V_a){\times}100$, where $V_a$ means the volume of the added water in the W/O emulsion and $V_s$ represents the volume of the separated water in the W/O emulsion for a desired storage time. The emulsion stability indices of W/O emulsion system at sorbitan trioleate, span 60, and tween 20 were $95.4{\pm}1.8$, $56.1{\pm}2.8$, and $41.6{\pm}2.2$ respectively. Furthermore, the differences between "VOLUMETRIC METHOD" and "Titus et al method" were less than 5.0 of ESI Value.

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