• Title, Summary, Keyword: hog cholera

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Histopathologic Studies on the Brain and Lymphoid Organs in Hog Cholera III. Encephalitis of Pigs and Rabbits (Hog Cholera 병돈(病豚)의 뇌(腦) 및 임파장기(淋巴臟器)에 관한 병리조직학적(病理組織學的) 연구(硏究) III. 뇌염소견(腦炎所見)에 대하여)

  • Kwak, Soo-Dong;Lee, Cha-Soo
    • Korean Journal of Veterinary Research
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    • v.22 no.2
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    • pp.197-209
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    • 1982
  • This study was undertaken to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the brain as well as clinical observations were carried out for the naturally and experimentally infected pigs with hog cholera viruses. Electron microscopically the vascular cuffings of the brain were also observed in the experiment. In addition, clinical and pathological studios were carried out in the rabbits inoculated with ALD, lapinized and isolated strain of hog cholera virus, respectively. The results obtained are as follows; Vascular cuffing of the brain was observed in about 97% of the natural cases and all of the experimental cases. Among the 496 cuffed blood vessels of natural cases, intramural cuffing (82.9%), intramural and perivascular cuffing (11.9%) and perivascular cuffing (5.2%) were seen, respectively. Electron microscopic findings on cuffed blood vessels of the brain were endothelial cellular degeneration, intramural separation and vacuolation, perivascular vacuolation and infiltration of pleomorphic lymphoid cells. In the rabbits dosed with tissue suspension of the lymphoid organs and isolated hog cholera virus, high body temperature and vascular cuffing of the brain were observed, meanwhile these changes were more significant in pre-injected cased with indian ink.

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Histopathologic Studies on the Brain and Lymphoid Organs in Hog Cholera I. Clinical and Pathological Observation in Hog Cholera (Hog Cholera 병돈(病豚)의 뇌(腦) 및 임파장기(淋巴臟器)에 관한 병리조직학적(病理組織學的) 연구(硏究) I. 임상(臨床) 및 병리해부학적(病理解剖學的) 관찰(觀察))

  • Kwak, Soo-Dong;Lee, Cha-Soo
    • Korean Journal of Veterinary Research
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    • v.22 no.1
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    • pp.31-36
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    • 1982
  • This study was taken to clarify the clinical signs and macroscopical lesions of pigs naturally infected with hog cholera. The clinical and macroscopical observation on the natural cases of hog cholera and experimental cases inoculated with ALD Virus and isolated virus strains were carried out. The results obtained are as follow; In clinical inspection of the natural cases, diarrhea (73.1%) blotching of ear (50.0%), staggering (42.3%), erythema of skin (40.0%), constipation (38.5%), conjunctivitis (32.7%) and dyspnea (30.8%) were observed. Dyspnea, constipation and erythema of skin were observed mainly in the experimental cases, however, staggering and conjunctivitis in pigs infected with ALD virus were found and convulsion and hemorrhage of skin of pigs infected with isolated virus were seen, respectively. The gross lesions of natural cases were hemorrhage of lymph node (82.5%), enteritis and hemorrhage of large intestine (65.0%), splenic infarction (57.5%), pneumonia (55.0%), gastritis and hemorrhage (52.5%), cardiac hemorrhage (40.0%) and renal petechiation (37.5%), while in the experimental cases, hemorrhage of lymph node, pneumonia, gastritis and hemorrhage, enteritis and hemorrhage of laryge intestine and splenic infarction were seen mainly.

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Histopathologic Studies on the Brain and Lymphoid Organs in Hog Cholera II. Necrotic Lesion and Inclusion Body in the Lymphoid Organ (Hog Cholera 병돈(病豚)의 뇌(腦) 및 임파장기(淋巴臟器)에 관한 병리조직학적(病理組織學的) 연구(硏究) II. 임파장기(淋巴臟器)의 괴사(壞死)와 봉입체출현(封入體出現))

  • Kwak, Soo-Dong;Lee, Cha-Soo
    • Korean Journal of Veterinary Research
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    • v.22 no.1
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    • pp.37-52
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    • 1982
  • This study was taken to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the necrotic lesion and inclusion body in the lymphoid organs were carried out in the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. Electron microscopic findings of the intranuclear inclusion bodies in the reticular cell of spleen and lymph node were also observed in the experimental cases. The results obtained are as follow, As the histological findings necrosis of lymphoid organs was observed mainly in the lymph follicle. The necrotic lymphoid organs were found to contain 35.0% in the natural and 37.5% in the experimental cases. Intranuclear inclusion bodies were found mainly in the reticular cells of lymphoid organ, the epithelium of bronchiole and alevolus, and the vascular endothelium of brain. These inclusion bodies were seen in 40.0% of the natural cases and all of the experiment. The inclusion body was appeared to compose of activated nucleoli and chromatin granules (interchromatin and perichromatin) by electron microscopy.

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Comparative Studies on the Free Amino Acids in Hog Cholera Infected Swine Tissues (돈(豚)콜레라 바이러스 감염조직(感染組織)의 유리(遊離)아미노산(酸)에 관(關)한 비교연구(比較硏究))

  • Yong, Mahn Joong
    • Korean Journal of Veterinary Research
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    • v.6 no.1
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    • pp.31-36
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    • 1966
  • The free amino acid contents in several tissues of swine were analyzed qualitatively by means of two dimentional paper chromatography. The tissues used were liver, kidney and spleen that were obtained from normal, immunized and hog cholera infected swines. The results obtained are as follows: 1. Liver: 20 amino acids were detected in normal, 17 in immunized and 15 in infected swines. 2. Kidney: 16 amino acids were detected in normal, 13 in immunized and infected swines. 3. Spleen: 15 amino acids were detected in normal in immunized and 13 in infected swines. 4. Glutamic acid, leucine, serine and threonine were present in high concentration in all of the cases examined. 5. The free amino acids were appeard to be decreased in the infected tissues with hog cholera virus.

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Immunohistochemical diagnosis of hog cholera with peroxidase-antiperoxidase(PAP) complex method (Peroxidase-antiperoxidase(PAP) 복합체법을 이용한 돼지콜레라의 면역조직화학적 진단)

  • Moon, Oun-gyeong;Cho, Hee-tack;Kim, Soon-bok
    • Korean Journal of Veterinary Research
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    • v.30 no.2
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    • pp.215-221
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    • 1990
  • The present study was intended to use the peroxidase-antiperoxidase method for the identification of hog cholera virus(HCV) in the lymphatic organs of HCV-infected pigs. Sections were incubated with primary antibody (rabbit anti-HCV polyclonal or mouse anti-HCV monoclonal), followed by incubation with linkserum (goat anti-rabbit IgG) in excess and rabbit or mouse PAP complex. The viral antigen was localized mainly in the cytoplasms of lymphoid cells and macrophages. Positive reaction cells were frequently detected in the marginal areas of the germinal centers of the spleens, and also found in the tensils and lymph nodes. The method approved to be highly specific for the identification of the virus and allowed a precise localization of the viral antigen in infected cells.

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Detection of Hog Cholera Virus from the Artificially Infected Pigs by Fluorescent Antibody Technique and END Method (형광항체법 및 END법에 의한 돼지 콜레라 감염돈에서의 바이러스 검출)

  • Kim, S.J.;Kang, B.J.
    • Korean Journal of Veterinary Research
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    • v.10 no.2
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    • pp.53-57
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    • 1970
  • Hog cholera (HC) virus detection from the artificially infected pigs was made using fluoreescent antibody technique (FAT) and END method. It was observed that the swine origin virulent was detected in most of the organs tested at the early stage of the infection, while the tissue culture attenuated virus was detected only in blood (transitionally), lung, and tonsil.

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Prevalence and Factors Associated with Hog Cholera(Classical Swine Fever) Outbreak in South Eastern Korea in 1996 (대구근교에서 1996년에 발생한 돼지 콜레라의 역학적 특성)

  • Kim Bong-Hwan;Cho Kwang-Hyun;Park Noh-Chan;Kwon Hyun-Il
    • Journal of the korean veterinary medical association
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    • v.33 no.9
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    • pp.544-553
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    • 1997
  • Outbreaks of hog cholera(HC; classical swine fever) in 10 farrow-to-finish farms of regional corporative swine unit in the vicinity of Taegu(southeastern part of Korea) were investigated during the period of 6months from January to June 1996. The disease

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END SN Antibody Titers of Sows and Piglets Vaccinated with Living HC Vaccine During '83 Hog Cholera Outbreaks in Korea ('83 돈(豚)콜레라 유행시(流行時)의 면역모돈(免疫母豚)과 자돈(仔豚)의 END혈청중화항체가(血淸中和抗體價) 조사(調査))

  • Jeon, Yun-seong;Yeh, Jae-gil;Seo, Ik-soo
    • Korean Journal of Veterinary Research
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    • v.25 no.1
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    • pp.69-75
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    • 1985
  • Hog cholera serum neutralizing antibody of piglets and sows were titrated by means of END SN method. The piglets of a variety of ages, precolostrally immunized with LOM living HC vaccine were subjected to the test. The sows were vaccinated with lapinized living HC vaccine after 25 days from the parturition. Throughout the studies the following results were obtained and summarised. 1. Hog cholera antibody titers of inbred sows immunized with lapinized living HC vaccine after 25 days from parturition were high except Hampshire group(Table 2). 2. Sows, different stage of the pregnancy or the day of parturition, and of 3 way crossed, that were immunized with lapinized living HC vaccine have shown no significant difference on HC antibody titer(Table 2, 3). 3. HC antibody titers of piglets, immunized with a single dose of LOM HC vaccine before feeding colostrum, were high in case of the younger group(1 week) compare to the older(7 week) (Table 4). 4. The piglets that were booster immunized with LOM HC vaccine at the age of 7 weeks have shown an inconsistent antibody titers(Table 5).

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Cloning and Sequence Analysis of Hog Cholera Virus(HCV) E2 Gene (돼지 콜레라 바이러스 E2 유전자의 클로닝 및 염기서열분석)

  • 이영기;강신웅;김선원;박성원;이종철;이청호
    • Journal of the Korean Society of Tobacco Science
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    • v.23 no.2
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    • pp.103-108
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    • 2001
  • Hog cholera virus(HCV) was purified from virus infected Bovine kidney cells. From this virus, total protein was analyzed by SDS-PAGE gel electrophoresis and about 55 kDa band of E2 envelope protein was detected. The viral RNA was purified and E2 cDNA was amplified by RT-PCR. E2 cDNA fragment was cloned to PCRII-TOPO cloning vector and named pE2. The analysis of nucleotide sequence showed that this E2 cDNA fragment inserted into pE2 was 1191 nucleotides long and coded 397 amino acids.

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