• Title, Summary, Keyword: inductively coupled plasma-mass spectrometry

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A Study on the Analytical Method of Trace Metal Ions in Sea Water by Inductively Coupled Plasma - Mass Spectrometry using Solid-Liquid Extraction Technique (유도결합 플라스마-질량분석법과 고체-액체 추출법을 이용한 해수중 미량금속의 분석에 관한 연구)

  • Lee, Won;Park, Kyung-Su;Kim, Eun Kyung;Hur, Young-Hoe
    • Analytical Science and Technology
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    • v.11 no.6
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    • pp.499-504
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    • 1998
  • An analytical method for the simultaneous measurement of trace Cu, Sn, and Bi in sea water has been investigated by Inductively Coupled Plasma-Mass Spectrometry. Amberlite IRC-718 resin was used as a solid phase in solid-liquid extraction technique for the removal of matrix interferences such as Na, S, P, and other polyatomic ion species. Recoveries of 99.8% for Cu, 99.6% for Sn, and 97.9% for Bi were obtained for the standard spiked sample. The developed method was applied to analysis of trace metals in sea water.

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Errors in Isotope Dilution Caused by Matrix-induced Mass Bias Effect in Quadrupole Inductively Coupled Plasma-Mass Spectrometry

  • Pak, Yong-Nam
    • Bulletin of the Korean Chemical Society
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    • v.35 no.12
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    • pp.3482-3488
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    • 2014
  • Matrix-induced mass bias and its effect on the accuracy of isotope ratio measurements have been examined for a quadrupole-based inductively coupled plasma-mass spectrometer (Q ICP-MS). Matrix-induced mass bias effect was directly proportional to % mass difference, and its magnitude varied for element and nebulizer flow rate. For a given element and conditions in a day, the effect was consistent. The isotope ratio of Cd106/Cd114 under $200{\mu}g\;g^{-1}$ U matrix deviated from the natural value significantly by 3.5%. When Cd 111 and Cd114 were used for the quantification of Cd with isotope dilution (ID) method, the average of differences between the calculated and measured concentrations was -0.034% for samples without matrix ($0.076{\mu}g\;g^{-1}$ to $0.21{\mu}g\;g^{-1}$ for the period of 6 months). However, the error was as large as 1.5% for samples with $200{\mu}g\;g^{-1}$ U. The error in ID caused by matrix could be larger when larger mass difference isotopes are used.

Accurate Analysis of Chromium in Foodstuffs by Using Inductively Coupled Plasma Mass Spectrometry with a Collision-Reaction Interface

  • Lee, Seung Ha;Kim, Ji Ae;Choi, Seung Hyeon;Kim, Young Soon;Choi, Dal Woong
    • Bulletin of the Korean Chemical Society
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    • v.34 no.6
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    • pp.1689-1692
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    • 2013
  • Food is a common source of chromium (Cr) exposure. However, it is difficult to analyze Cr in complex food matrices by using inductively coupled plasma mass spectrometry (ICP-MS) because the major isotope, $^{52}Cr$, is masked by interference generated by the sample matrix and the plasma gas. Among the systems available to minimize interference, the recently developed collision-reaction interface (CRI) has a different structure relative to that of other systems (e.g., collision cell technology, octopole reaction system, and dynamic reaction cell) that were designed as a chamber between the skimmer cone and quadrupole. The CRI system introduces collision or reaction gas directly into the plasma region through a modified hole of skimmer cone. We evaluated the use of an CRI ICP-MS system to minimize polyatomic interference of $^{52}Cr$ and $^{53}Cr$ in various foodstuffs. The $^{52}Cr$ concentrations measured in the standard mode were 2-3 times higher than the certified values. This analytical method based on an ICP-MS system equipped with a CRI of helium gas was effective for Cr analysis in complex food matrices.

Determination of Dibutyltin in Sediments Using Isotope Dilution Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry

  • Yim, Yong-Hyeon;Park, Ji-Youn;Han, Myung-Sub;Park, Mi-Kyung;Kim, Byung-Joo;Lim, Young-Ran;Hwang, Eui-Jin;So, Hun-Young
    • Bulletin of the Korean Chemical Society
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    • v.26 no.3
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    • pp.440-446
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    • 2005
  • A method is described for the determination of dibutyltin (DBT) in sediment by isotope dilution using liquid chromatography inductively-coupled plasma/mass spectrometry (LC-ICP/MS). To achieve the highest accuracy and precision, special attentions are paid in optimization and evaluation of overall processes of the analysis including extraction of analytes, characterization of the standards used for calibration and LC-ICP/MS conditions. An approach for characterization of natural abundance DBT standard has been developed by combining inductively-coupled plasma/optical emission spectrometry (ICP/OES) and LC-ICP/MS for the total Sn assay and the analysis of Sn species present as impurities, respectively. An excellent LC condition for separation of organotin species was found, which is suitable for simultaneous DBT and tributyltin (TBT) analysis as well as impurity analysis of DBT standards. Microwave extraction condition was also optimized for high efficiency while preventing species transformation. The present method determines the amount contents of DBT in sediments with expanded uncertainty of less than 5% and its result shows high degree of equivalence with reference values of an international inter-comparison and a certified reference material (CRM) within stated uncertainties.

Some Effects of Acid Concentrations in Inductively Coupled Plasma Atomic Emission Spectrometry and Inductively Coupled Plasma Mass Spectrometry (유도결합 플라즈마 원자방출분광법 및 질량분석법에서 산의 농도에 의한 영향)

  • Cho, Man-Sik;Lim, Heoungbin;Kim, Young-Sang;Lee, Kwang-Woo
    • Analytical Science and Technology
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    • v.5 no.3
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    • pp.277-283
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    • 1992
  • Acid effects on the ICP-AES signals are studied as the concentrations of nitric acid, hydrochloric acid, sulfuric acid, and 1:1 mixture of nitric acid and hydrochloric acid are changed. Almost all analyte signals are depressed. The extent of the depression due to the pressence of the acids became to be pecular when the acid concentration was over 1%. Among the acids used, the suppression due to sulfuric acid is most severe and unexpectable. The ratios of the analyte signal to Ar signal and the Mg II signal to Mg I signal are measured as the concentration of the acids changed. In this study, it is proved that the main reason of the signal reduction is the change in the nebulization efficiency, for example, droplet size distribution, viscosity and surface tension variation, not the alteration of plasma excitation characteristics. There was no relationship found between ionization potential and analyte signal reduction in ICP-MS.

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Multielement Analysis in Airborne Particulate Matter $(PM_{10})$ by INAA, ICP and AAS (INAA.ICP.AAS를 이용한 대기먼지 $(PM_{10})$의 다원소분석)

  • 정용삼;문종화;정영주;박광원;이길용;윤윤열;심상권;조경행;한명섭
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.4
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    • pp.495-503
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    • 1999
  • Airborne particulate matter $(PM_{10})$ collected using high volume air sampler and silica fiber filter were analyzed by Instrumental Neutron Activation Analysis(INAA), Inductively Coupled Plasma Atomic Emission Spectrometry(ICP-AES) and Atomic Absorption Spectrometry(AAS), and the results were compared with each other. 30~40 trace elements in environmental standard reference materials(NIST SRM 1648 and NIES CRM No.8) were analyzed for the analytical quality control. The relative error for two-third of elements detected was less than 10%, and the standard deviation was less than 15%. During the sampling period for 24 hours, the mass concentration of total suspended particulate was 36.1$\mu\textrm{g}$/㎥ and the value is lower than the critical level in Korea. In the results of NAA, the elements of Al, As, Ba, Fe, La, Mg, Na, Sb, Zn were well agreed with those of other methods. In statistical estimation between different methods, the deviation of Al, Ba, Cr, Fe was less than 10% and quite reliable.

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Trace level analysis of Pb in plasma by inductively coupled plasma/mass spectrometry (유도결합플라즈마 질량분석법을 이용한 혈장 중 극미량 납 분석)

  • Lee, Sung-Bae;Yang, Jeong-Sun;Choi, Sung-Bong;Shin, Ho-Sang
    • Analytical Science and Technology
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    • v.25 no.3
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    • pp.190-196
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    • 2012
  • The human exposure of lead has usually detected the amount of lead in the whole blood, however, this method has a shortcoming to give the information on the short-term exposure to lead. In that sense, it is desirable to estimates the level of lead in plasma to draw the chronic bio-marker of lead exposure even though it is difficult to measure lead of several ng/L. An inductively coupled plasma-mass spectrometry (ICP-MS) method was developed for determining lead in plasma as the chronic bio-marker of lead of workers. To minimize the contamination of lead from the environment, we constructed class 1,000 clean room and compared the amount of floating dust before and after the operation of the clean room. The limit of detection (LOD) and the limit of quantification (LOQ) of lead in fetal bovine serum were 4.3 ng/L and 12.2 ng/L by NIOSH method (statistical calculation method) and 7.0 ng/L and 22.1 ng/L by signal/noise ratio, respectively. The accuracy was in a range of 92.3-101.3%, and the precision of the assay was less than 4% in the samples spiked in the concentration of 20 ng/L and 2,000 ng/L. The method was simple, reproducible and sensitive enough to permit reliable analysis of lead to the ng/L level in plasma and/or serum. The method was also useful for the biological monitoring of chronic exposure to lead.