• Title, Summary, Keyword: magnetic resonance

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Synthesis and Characterization of a Receptor-Targeting Contrast Agent

  • Yang, Taegyun;Park, Ji-Hyung;Lee, Seung-Cheol;Kim, Cheol-Su;Cho, Jee-Hyun;Lee, Chul-Hyun;Cheong, Chae-Joon
    • Journal of the Korean Magnetic Resonance Society
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    • v.7 no.1
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    • pp.46-54
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    • 2003
  • We synthesized a contrast agent for MRI that is capable of binding to the ABP-1 receptor and enhancing the contrast of the targeted cells. We used a lysine dendrimer (G=3)DTPA[Gd] as the contrast agent and synthesized a biotinylated polyclonal antibody for ABP-1 as the first antibody. Lysine dendrimers were prepared using the solid phase peptide synthesis method.$^3$ Amino-terminated lysine dendrimers were then coupled to DTPA using the anhydride method. Gd was complexed with the DTPA-lysine dendrimer in an acidic solution of 3 eq GdCl$_3$ to one of DTPA. The lysine dendrimer-DTPA[Gd] and avidin were conjugated in MES solution, pH 6.0, using EDC as the coupling reagent. The biotin-avidin system was used to link the polyclonal antibody and contrast agent. K562 cells were used for imaging.

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HIGH RESOLUTION IMAGING IN 37 MRI SYSTEM

  • Park, Jeong-Il;Choi, Kim-S.;Choe, Bo-Young;Suh, Tae-Suk;Lee, Hyoung-Koo;Shin, Kyung-Sub;Lee, Heung-Kyu
    • Proceedings of the Korean Society of Medical Physics Conference
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    • pp.423-424
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    • 1999
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Breast Magnetic Resonance Image (MRI) Guideline: Breast Imaging Study Group of Korean Society of Magnetic Resonance in Medicine Recommendations

  • Choi, Seon Hyeong;Kang, Bong Joo;Jung, Seung Eun
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.4
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    • pp.205-208
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    • 2018
  • The purpose of this study is to establish an appropriate protocol for breast magnetic resonance imaging (MRI) in the discipline of image quality standards. The intention of the protocol is to increase effectiveness of medical image information exchange involved in construction, activation, and exchange of clinical information for healthcare.