• Title, Summary, Keyword: neuropsychiatric disease

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A Study on Neuropsychiatric Symptoms and Signs of Disease Pattern in Korean Medicine (한의병증에 대한 신경정신과적 증상 기술 연구)

  • Jang, Jae-Soon;Kim, Ka-Na;Cho, Seung-Hun
    • Journal of Oriental Neuropsychiatry
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    • v.27 no.4
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    • pp.249-259
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    • 2016
  • Objectives: This study aimed to develop a standard understanding of neuropsychiatric symptoms and signs of Disease Pattern Identification/syndrome in Korean Medicine. Methods: We investigated various published articles, and the proposals are based on a comparative analysis between Korean medicine literature and DSM5, ICD-10. To improve our understanding, we engaged in a consultation through discussions with the advisory committee. Results: We describe the physical and neuropsychiatric symptoms in a modern sense of the major disease Pattern in Korean Medicine. We also proposed a profound understanding of the neuropsychiatric symptoms and signs of Disease Pattern Identification/syndrome in Korean Medicine. Conclusions: Compared with DSM5, ICD-10, the system of neuropsychiatric diagnosis in Korean medicine, could be profoundly organized into a system in a modern sense. It would be helpful to apply this understanding to clinical practices. There are several points of consideration in this study. The system of neuropsychiatric diagnosis in Korean medicine cannot be a perfect match for DSM5 or ICD-10. In addition, we could not reach a complete consensus on the disease pattern. Although there are some limitations to this study, it is meaningful to have an understanding of the neuropsychiatric symptoms and signs in Korean medicine through discussions with the advisory committee. This trial is expected to be applicable to related research in the future.

Effects of Herbal Medicine (Gan Mai Da Zao Decoction) on Several Types of Neuropsychiatric Disorders in an Animal Model: A Systematic Review - Herbal medicine for animal studies of neuropsychiatric diseases -

  • Kim, Su Ran;Lee, Hye Won;Jun, Ji Hee;Ko, Byoung-Seob
    • Journal of Pharmacopuncture
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    • v.20 no.1
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    • pp.5-9
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    • 2017
  • Objectives: Gan Mai Da Zao (GMDZ) decoction is widely used for the treatment of various diseases of the internal organ and of the central nervous system. The aim of this study is to investigate the effects of GMDZ decoction on neuropsychiatric disorders in an animal model. Methods: We searched seven databases for randomized animal studies published until April 2015: Pubmed, four Korean databases (DBpia, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, and Research Information Sharing Service), and one Chinese database (China National Knowledge Infrastructure). The randomized animal studies were included if the effects of GMDZ decoction were tested on neuropsychiatric disorders. All articles were read in full and extracted predefined criteria by two independent reviewers. Results: From a total of 258 hits, six randomized controlled animal studies were included. Five studies used a Sprague Dawley rat model for acute psychological stress, post-traumatic stress disorders, and unpredictable mild stress depression whereas one study used a Kunming mouse model for prenatal depression. The results of the studies showed that GMDZ decoction improved the related outcomes. Conclusion: Regardless of the dose and concentration used, GMDZ decoction significantly improved neuropsychiatric disease-related outcomes in animal models. However, additional systematic and extensive studies should be conducted to establish a strong conclusion.

A Study on the Sasang Constitutional application of Clinical Acupuncture (임상 침법의 사상의학적 활용)

  • Yoo, Jong-Hyang;Kim, Yun-Young;Park, Ki-Hyeun;Jang, Eun-Su;Lee, Si-Woo
    • Korean Journal of Oriental Medicine
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    • v.16 no.3
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    • pp.15-22
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    • 2010
  • Objective : This study aims to search Four-constitution Medicine based acupuncture by investigators and its effect on constitution-specific symptoms. Method : Among 463 oriental medical doctors who are the members of society of Four-constitution Medicine, 191 results are collected. The items of the questionnaire are sex, age, work experiences, working type, constitution diagnosis & prescription, the use of constitution acupuncture and so on. Result : The proportion of acupuncture treatment applied constitution-based acupuncture to patients are "Must Use" 12.6%, "Almost Use" 14.1%, "Sometimes Use" 42.9% and "Never Use" is 1.0%. The average ratio of patients treated by constitution-based acupuncture to all patients is 47%. 1. Digestive tract disease is found to be the most effective disease with constitution based acupuncture. Musculoskelectal problems, cardiovascular disease, respiratory disease, neuropsychiatric disease and urogenital disease are followed. On the oriental medicine, spleen system disease is the most frequently applied and heart system disease, neuropsychiatric disease, liver system disease, locomotorium disease and pulmonary system disease are followed. 2. Acupuncture therapeutic measures are different according to disease. For example, Sa-am acupuncture is the most widely used for spleen system disease, locomotorium disease, heart system disease, neuropsychiatric disease, pulmonary system disease. Eight constitution medicine acupuncture is effective for ophthalmic & otolaryngologic disease. Conclusion : This study is to investigate constitution-based acupuncture technique. In conclusion, the most widely used technique is Sa-am acupuncture and it is the most successful in treating digestive tract disease.

A Study of clinical document in relation to Neuropsychiatric disease(Focusing of Ancient Chinese (Song<宋>, Keum<金>, Won<元>, Myung<明> clinical document) (신경정신과(神經精神科) 질환(疾患)과 관련(關聯)된 의안(醫案)의 연구(硏究) (중국(中國) 송(宋)$\cdot$금(金)$\cdot$원(元)$\cdot$명(明) 시대(時代) 의안(醫案)을 중심(中心)으로))

  • Kwon Bo-Hyung;Ku Byung-Su
    • Journal of Oriental Neuropsychiatry
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    • v.8 no.1
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    • pp.215-235
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    • 1997
  • according to study of clinical document in relation to Neuropsychiatric disease in Ancient Chinese(Song, Keum, Won, Myung) clinical document the result were obtained as follows. 1. A main point is Jeul-Jin<切診> in diagnosis, that is Hyun-Maeg<弦脈> is liver disease, Whual Mag<滑脈> is gallbladder disease, Sag Mag<數脈> is fever.2. Doctors in Song<宋>, Keum<金>,Won<元> enumerationed many diseases are cause by emotion.3. Oriental psychotherapy that Diseases caused by surprising must be cure by surprising is like to systematic desensitization in Westem.4. Oriental psychotherapy that pseudopsychosis must be cure by patient rely on doctor is like to suggestive therapy in western.5. It is similar to suggestive therapy in western medicine that Sadness ,anguish and frustration induce disease.6. Headache is caused by fever, energy deficience and angry.7. Imsomnia is not caused by hsart disease, but gallbladder or liver.8. Schizophrenia is caused by shocking and a sort of fever.9. Epilepsy is caused by a sort of fever, shocking and fetal disease.10 Schizophrenia(in case of manic state) is caused by fever and shocking, and imaginary pregnancy is considered as schizophrenia.

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Neuropsychiatric Aspects of Pulmonary Disease (호흡기 질환의 신경정신과적 측면)

  • Nam, Beom-Woo
    • Korean Journal of Psychosomatic Medicine
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    • v.17 no.2
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    • pp.45-51
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    • 2009
  • Pulmonary diseases distress millions of people worldwide. Numerous studies have shown an association between pulmonary disease and psychiatric disorders. Despite this, little is known about the treatment of psychiatric disorder in patients with pulmonary disease. The three main goals of this article are 1) to discuss the major disorders such as asthma, chronic obstructive pulmonary disease, hyperventilation, tuberculosis, lung cancer that most clinicians see in practice, 2) to provide an information about psychiatric treatment such as anxiety, depression, psychosis in pulmonary disease, and 3) to provide some clinically relevant suggestions about pharmacologic interactions between pulmonary and psychotropic drugs.

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Potential Significance of Eyeblinks as a Behavior Marker of Neuropsychiatric Disorders (눈깜박임의 정신질환 행동지표로서의 가능성에 대한 고찰)

  • Oh, Ji-Hoon;Jeong, Jae-Seung
    • Korean Journal of Biological Psychiatry
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    • v.19 no.1
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    • pp.17-28
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    • 2012
  • The primary purpose of this review is to present an overview of relationship between human spontaneous eyeblinking and internal cognitive processes. The second purpose is to address the neural substrates of human eyeblinking based on recent studies focusing on the central dopaminergic system and to explore the significance of spontaneous eyeblinks in neuropsychiatric disorders. We reviewed recent and previous studies on eyeblink patterns under various cognitive tasks. We also reviewed neural substrates of eyeblinking, particularly based on the central dopaminergic system. This paper suggests that spontaneous eyeblinks are highly correlated with various cognitive processes and the activity of central dopaminergic system. Various neuropsychiatric disorders are related to the alteration of the occurrence of eyeblinking. Spontaneous eyeblinking is the unique human behavior that occurs regularly without conscious effort. It is known that the rate of eyeblinking is modulated by internal cognitive processes and dopamine-related neuropsychiatric disorders. Further research is required to how the temporal dynamics of spontaneous eyeblinking is correlated with the disease activity and progression.

Factors Affecting Caregiver Burden in Caregivers of Patients with Parkinson's Disease (파킨슨병 환자 부양자의 부양부담에 영향을 미치는 요인)

  • Kim, Dong Won;Bae, Eun Sook
    • Korean Journal of Adult Nursing
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    • v.27 no.3
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    • pp.283-293
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    • 2015
  • Purpose: Depression is a common sign of suffering among the patients with Parkinson's disease (PD). Frequent and severe neuropsychiatric symptoms lead to high levels of distress in patients and their caregivers, which results in the high levels of caregiver burden. The aim of this study was to determine the predictors of caregiver burden in caregivers of the patients with Parkinson's disease (PD). Methods: The study included 183 consecutive PD patients and their caregivers. Patients were assessed using the Hoehn and Yahr scale, Mini Mental State Examination (MMSE), Beck Depression Inventory (BDI), and Schwab and England Activities of Daily Living Scale. Caregivers' depressive symptoms were evaluated using the Caregiver Burden Inventor (CBI), BDI, and World Health Organization Quality of Life Scale. Results: All of the patients reported one or more neuropsychiatric symptoms. Patients' and caregivers' depressive symptoms, caregivers' age and education, time for caregiving, and quality of life were significantly associated with the increased caregiver burden. After controlling the level of education as a potential confounding variable, depression in both patients and caregivers, time for caregiving, and quality of life explained 45.6% of the variance in caregiver burden. Conclusion: Substantial attention needs to be given to the early identification of depression in PD patients and their caregivers to improve caregivers' quality of life and burden.

Two Cases of Systemic Lupus Erythematosus with Cerebrovascular Involvement (뇌 혈관계를 침범한 전신성 홍반성 루푸스 2례)

  • Kim, Bong-Jun;Lee, Eun-Young;Hong, Young-Hoon;Park, Ki-Do;Song, Young-Doo;Lee, Choong-Ki;Shim, Young-Ran
    • Yeungnam University Journal of Medicine
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    • v.15 no.2
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    • pp.371-380
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    • 1998
  • Systemic lupus erythematosus(SLE) is an autoimmune disease which may affect many different organs and disclose various clinical manifestations. Recently central nervous system(CNS) involvement has been recognized as an increasingly significant contributor to morbidity and mortality of SLE. The clinical manifestations of CNS-lupus are highly variable and range from mild cognitive dysfunction, movement disorder, headache, psychosis to life-threatening stroke and coma. Among the neuropsychiatric disorders encountered in patients with SLE, cerebrovascular disease has been a relatively rare complication. The diagnosis and management of CNS-lupus is difficult because of the lack of useful diagnostic methods. If cerebrovascular involvement is suspected, aggressive treatment such as high dose steroid, immunosuppressive therapy, plasma exchange may be required to reduce high mortality rate. We experienced 2 cases cerebrovascular dis eases occurring in SLE patients which presented with various neuropsychiatric manifestations. They were diagnosed as CNS-lupus by neuropsychiatric symptoms, brain MRI, and BEG, and showed good response to high dose steroid pulse therapy.

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Adverse health effects of particulate matter (미세먼지의 건강영향)

  • Kyung, Sun Young;Jeong, Sung Hwan
    • Journal of the Korean Medical Association
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    • v.60 no.5
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    • pp.391-398
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    • 2017
  • Particulate matter (PM) is known to have serious health effects in individuals with respiratory or cardiovascular disease. Recent studies have shown that they also have noxious effects on cerebrovascular, metabolic, and neuropsychiatric disorders, as well as pregnancy. The aim of this study is to review the various diseases associated with PM in each human organ. Regarding respiratory diseases, PM has been associated with increased acute exacerbation in patients with chronic obstructive pulmonary disease, bronchial asthma, and several other respiratory diseases, resulting in increased hospitalization and mortality. In addition, PM increases the risk of lung cancer and accelerates the decline of lung function. Individuals with cardiovascular conditions such as ischemic heart disease, heart failure, hypertension, arrhythmia, and atherosclerosis have been also found to exhibit increased morbidity and mortality when exposed to PM. PM also has been reported to cause insulin resistance and to induce increasing rates of diabetes. During pregnancy, prolonged exposure to PM has been associated with increased rates of low birth weight and preterm birth. In individuals with neurological diseases, exposure to PM reduces cognitive ability and memory, and increases stroke incidence. It has been reported that PM also exacerbates psychiatric conditions, particularly depression and anxiety disorder. Thus, PM has been shown to exert very noxious health effects on the human body, with impacts including effects on respiratory and cerebrovascular diseases, cardiovascular diseases, neuropsychiatric diseases, and low birth weight.

Study of oriental medical science documentory records of tinnitus and neuropsychiatric aspect of hiccup (이명(耳鳴)에 관한 정신의학적 문헌고찰(文獻考察))

  • Jang, Young-Ju;Jung, In-Chul;Lee, Sang-Ryong
    • Journal of Haehwa Medicine
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    • v.18 no.1
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    • pp.67-81
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    • 2009
  • 1. According to causes of attack and symptoms, tinnitus is divided into two categories; deficiency and excess. Causes of excess syndrome of tinnitus were wind fire in the liver and gallbladder, phlegm fire, blood stagnation, and heat in meridian system and the causes of deficiency syndrome of tinnitus were qi deficiency or blood deficiency after an illness or delivery, yin deficiency of liver and kidney, and deficiency of sea of the marrow. 2. Tinnitus was related to the vicera and bowels, especially to liver, gallbladder and urinary bladder. 3. In regard of method of treatment, tonify kidney, nourish heart, clear the liver and discharge heat are used according to visera and bowel theory. Clear phlegm and downbear fire are used for phlegm fire. Tonify spleen and kidney is used for ancestral vessel deficiency. Dispel wind and dissipate fire can be used according to theory of five elements' motion and six kinds of natural factors. 4. The basal meridian of acupuncture and moxibustion treatment were the channels of Shaoyang.. 5. Regarding neuropsychiatric aspect of tinnitus, sudden anger and depression of mind were the main mechanism of disease and liver fire was the main cause. The prescriptions for neuropsychiatric tinnitus were Dangguiyonghuehwan, and Yongdamsagantang.

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