• 제목, 요약, 키워드: pulsed electromagnetic fields

검색결과 18건 처리시간 0.042초

The Effects of Pulsed Elctromagnetic Fields on Expression of Neurotrophic Factors after Spinal Cord Hemisection in Rats

  • Kang, Ji-Hyuk;Park, Sang-Young;Lee, Yun-Seob
    • Journal of Magnetics
    • /
    • v.16 no.3
    • /
    • pp.253-258
    • /
    • 2011
  • The purpose of this study was to identify the effect of pulsed electromagnetic fields on the expression of neurotrophic factors after spinal cord injury. Sprague-Dawley male rats were given a spinal cord hemisection and randomly divided into 2 groups, the control and experimental groups. The experimental group was administered a fifteen minutes session of pulsed electromagnetic field once a day, five days a week. In order to observe the effect of these pulsed electromagnetic fields, this study observed the BDNF expression in the rat's lumbar spinal cord and the H&E staining in the gastrocnemius at 3, 7, 14, 21 days group after spinal cord hemisection. The results of this showed that the immunoreactivity of the BDNF in the rat's spinal cord gradually increased in each group. At 21 days, there is a significant difference between the control and experimental groups. The morphological shape of the gastrocnemius was gradually changed from 3days to 21days, and the gastrocnemius at 21 days was significantly degraded. However, the experimental group showed a slightly more organized gastrocnemius than the control group at 21days. The Results of this study suggest that pulsed electromagnetic field application decreases the degeneration of a rat's gastrocnemius morphology, and increases the immunoreactivity of the BDNF in the rat's spinal cord after spinal cord hemisection.

맥동전자장이 고지혈증 흰쥐의 혈액 성분, 항산화 효소 및 활성 산소에 미치는 영향 (The Effects of Pulsed Electromagnetic Fields on Blood components, Antioxidant enzymes and Reactive Oxygen in Hyperlipidemic Rats)

  • 방현수;정인호;이상덕
    • 디지털융복합연구
    • /
    • v.12 no.7
    • /
    • pp.349-356
    • /
    • 2014
  • 본 연구는 맥동전자장이 고지혈증 관련 혈액 성분, 항산화 효소와 활성 산소에 어떠한 영향을 미치는 지를 관찰하기 위하여 실시하였다. 실험군은 정상식이군, 고지방식이군과 고지방식이-맥동전자장 적용군의 3군으로 나누었다. 맥동 전자장은 맥동 전자장 에너지 치료기를 이용하였다. 혈액 성분의 검사 항목은 혈당, 유리지방산, 중성지방 및 콜레스테롤, 인슐린이고, 항산화 효소와 활성 산소의 검사는 글루타치온, 글루타치온 환원효소, 크산틴, 과산화지질을 측정하였다. 그 결과 맥동전자장 적용은 혈액 구성성분과 GSH와 GRD를 고지장식이 수준에서 정상식이 수준으로 상승시켰으며, XO와 MDA는 고지방식이 수준에서 정상 식이 수준으로 낮추어 주는 개선효과를 나타내었다. 그러므로 맥동전자장의 적용은 고지혈증 흰쥐의 혈액성분의 변화, 항산화 효소의 증가, 활성 산화의 억제에 효과적인 치료 방법이라 할 수 있다.

Pulsed Electromagnetic Fields to Influence Pain and Muscle Healing Following Muscle Injury in Rats

  • Koo, Hyun-Mo;Na, Sang-Su;Yong, Min-Sik
    • Journal of Magnetics
    • /
    • v.20 no.4
    • /
    • pp.377-380
    • /
    • 2015
  • Muscle contusion has a negative effect on muscle function. Although several studies showed that pain control and muscle recovery is facilitated by pulsed electromagnetic fields (PEMF), there has not been much research regarding the specific effects of PEMF on them. The aim of the present study is to investigate effects of PEMF on pain and muscle recovery following extensor digitorum longus (EDL) contusion injury through measuring the expression of the c-fos proto-oncogene and nerve growth factor (NGF). Significantly reduced c-fos expression in the spinal cord was shown in PEMF groups compared with control (CON) groups. There was no significant difference between PEMF1 and CON1, but significantly increased NGF expression was shown in PEMF3 and PEMF5 compared with in CON groups, where the numbers in the group names are the days from contusion. In conclusion, PEMF could be used to not only reduce pain in muscle injuries by down-regulating c-fos expression in the spinal cord, but it could also influence muscle healing through increasing NGF expression in the injured muscle.

Half sine-wave pulsed electromagnetic fields 내에서 교정력에 의한 치아 이동에 대한 연구 (A STUDY ON THE ORTHODONTIC TOOTH MOVEMENT UNDER HALF SINE-WAVE PULSED ELECTROMAGNETIC FIELDS)

  • 김영준;유영규
    • 대한치과교정학회지
    • /
    • v.24 no.4
    • /
    • pp.897-916
    • /
    • 1994
  • The biologic potential, which is different from the piezoelectric signals, relates tooth movement at least in part to changes in bone metaboliosm in bioelectric theory. The purpose of this experiment was to determine wheather the application of half sine-wave pulsed electromagnetic fields (HSPEMF) could increase both the rate and amount of orthodontic tooth movement. Forty-three male Hartley guinea pigs, weighting approximately 255g, were utilized in this study. The animals were 35 days old at the start of the study. Laterally directed orthodontic force was applied to the maxillary central incisors of 40 Hartley guinea pigs (20 experimental, 20 control). According to the amount of orthodontic force (6g, 12g), they were divided into two sub-groups (10 experimental I, 10 experimental II, 10 control I, 10 control II). During the experimental period, experimental animals were placed in plastic animal holders with their heads positioned in an area of uniform electromagnetic field. Control animals were placed in similar plastic holders that did not carry the electric apparatus. The results were as follows : 1. The application of a HSPEMF to the experimental groups significantly increase the final amount of orthodontic tooth movement observed over a 10-day experimental period. 2. The application of a HSPEMF to the experimental groups significantly increase the velocity of orthodontic tooth movement observed over a 10-day experimental period. 3. There was no significant difference in the final amount of orthodontic tooth movement at the fourth day to the eighth day, but there was significant difference in the final amount of orthodontic tooth movement at the nineth, tenth day during a 10-day experimental period. 4. After 10 days of HSPEMF exposure & orthodontic force, the experimental groups demonstrated more osteodasts in the pressure side than control groups.

  • PDF

Pulsed Ultrasound and Pulsed Electromagnetic Field in the Treatment of Muscle Contusion in Rats

  • Cheon, Song-Hee;Lee, Sun-Min
    • Journal of Magnetics
    • /
    • v.17 no.3
    • /
    • pp.225-228
    • /
    • 2012
  • Muscle contusion usually results from a direct blunt impact and is frequently associated with contact sports. Muscle contusion results from microscopic muscle fiber and capillary disruption causing a microhemorrhage dissecting torn fibers and remaining viable muscle fibers. Recent studies concluded that some physical methods, including pulsed ultrasound (PU) and pulsed electromagnetic field (PEMF) treatment, accelerate and facilitate wound healing, improve scar quality and have beneficial effects on muscle and tendon healing. However, there are few studies on the effects of the early use of physical methods, such as PU and PEMF, on the expression of neurotrophic factors. The objective of this study was to investigate the effects of the early application of PU and PEMF, measured through the expression of BDNF in the muscles (gastrocnemius) and spinal cords of rats after skeletal muscle contusion. In the spinal cords and muscles, there was a significant increase of BDNF expression in the PEMF and PU groups, a greater increase was found in the PEMF group than in the PU group. In conclusion, PEMF is a useful therapeutic method that improves muscle healing after muscle contusion.

The Effect of a Pulsed Electromagnetic Field with Time on Pain in Muscle Crushed Rat Model

  • Kim, Min-Hee;Cheon, Song-Hee
    • Journal of Magnetics
    • /
    • v.17 no.1
    • /
    • pp.68-71
    • /
    • 2012
  • Acute injuries to skeletal muscles can lead to significant pain and disability. Muscle pain results in muscle weakness and range of motion (ROM) decreases. Pulsed electromagnetic fields (PEMF) promote tissue repair, healing rates and reduce musculoskeletal pain. The results of many previous studies suggest that PEMF can contribute to chronic pain reduction, particularly in musculoskeletal injurys. However, we do not have enough information of its effects compared to a placebo. The principal objective of this study was to investigate differences in acute pain induced by the direct destruction of muscle tissue (extensor digitorum) with varying times of the application of PEMF, measured through the expression of c-fos on the spinal cord. Significant reduction of pain was found in groups exposed to PEMF and the group exposed to PEMF immediately after muscle injury showed the most significant differences. In conclusion, PEMF may be a useful strategy in reducing acute pain in muscle injury.

가토 두개부 골결손에서 맥동전자기장이 골형성에 미치는 영향에 관한 연구 (A STUDY OF EFFECT OF PULSED ELECTROMAGNETIC FIELDS ON OSTEOGENESIS IN RABBIT CRANIAL BONE DEFECT)

  • 황경균;이종환;김명진;심광섭;김종원
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • v.28 no.4
    • /
    • pp.264-273
    • /
    • 2002
  • Pulsed electromagnetic field (PEMF) was used first to induce osteogenesis in 1974. The appliance which was consisted of the Helmholtz coil configuration have used to osteogensis. The objective of this study was to determine whether PEMF, a frequency of 100 Hz and magnetic field strength of 38 gauss applied to the calvarial defect in rabbit, could affect the induction of osteogenesis and the healing of the graft bone. This field should not produce excitation of nerve or muscle and heating the tissue. To evaluate the effect of PEMF on osteogenesis, 16 rabbit under the same condition was divided into 8 experimental groups and 8 control groups. 10 mm calvarial bone defects were formed around sagittal suture. The defect of left side was left without graft while the defect of right side was grafted by bone harvested from left side. A pulsed electromagnetic field was applied for 8 hours per day. Each group was sacrificed after 1 week, 2 weeks, 4 weeks, 8 weeks. Microscopic specimens were obtained from the calvarial bone defects and surrounding tissue using Hematoxylin-Eosin staining method. The results were as follows. 1. In the group which pulsed electromagnetic field was applied, new bone formation filled up the defect was observed after 4 and 8 weeks effectively. 2. There are no difference in the healing period for the fusion between the bone and graft bone. According to the result, the PEMF with 38 Gauss, 100 Hz was very effective in the healing of bone defect and new bone formation. So The PEMF will be useful in clinical aspect for oseteogenesis.

흰쥐에서 반회후두신경 손상후 Pulsed electromagnetic fields(PEMFs)가 기능 회복에 미치는 영향

  • 정성민;구태완;조윤희;정승용;이재연;조선희;한후재;김현태
    • 대한음성언어의학회:학술대회논문집
    • /
    • /
    • pp.175-175
    • /
    • 1999
  • 배경 및 목적 : 성대마비환자에서 마비된 성대의 기능회복을 위해 여러 가지 방법으로 신경재지배를 시도하였으나 대부분이 misdirected reinnervation에 의한 후두의 synkinesis로 임상적으로 널리 이용되지 못하고 아직까지는 성대내전술등으로 음성의 질을 개선시키는 정도로만 치료하고 있는 실정이다 최근 복원에서는 반회후두신경의 절단 후 일차봉합에 의한 신경 재지배 후 후윤상피열근에 만성전기자극을 주었으나 자극을 주지 않은 대조군에 비해 후두기능회복이 더 잘된다는 결과를 확인하지 못한바 있다. 1980년대부터 pulsed electromagnetic fields (PEMFs)가 조직내에 ionic currents를 유도하여 cellular functions을 변화시킨다는 것을 보고된 이래로 PEMFs는 골절의 불유합이 있는 환자들에게 임상적으로 이용되고 있으며 최근 동물실험에서 흰쥐의 절단된 sciati nerve, common peroneal nerve, facial nerve의 신경재생을 촉진시켜 신경 재생이 조기에 되고 기능적으로 더 잘 회복되는 것으로 보고 있다. 이에 본 연구에서는 신경재생이 되더라도 기능적 회복이 힘든 것으로 알려진 반회후두신경의 재생 및 후두기능 회복에 대한 PEMFs의 영향을 알아보고자 하였다. (중략)

  • PDF

Design Study for Pulsed Proton Beam Generation

  • Kim, Han-Sung;Kwon, Hyeok-Jung;Seol, Kyung-Tae;Cho, Yong-Sub
    • Nuclear Engineering and Technology
    • /
    • v.48 no.1
    • /
    • pp.189-199
    • /
    • 2016
  • Fast neutrons with a broad energy spectrum, with which it is possible to evaluate nuclear data for various research fields such as medical applications and the development of fusion reactors, can be generated by irradiating proton beams on target materials such as beryllium. To generate short-pulse proton beam, we adopted a deflector and slit system. In a simple deflector with slit system, most of the proton beam is blocked by the slit, especially when the beam pulse width is short. Therefore, the available beam current is very low, which results in low neutron flux. In this study, we proposed beam modulation using a buncher cavity to increase the available beam current. The ideal field pattern for the buncher cavity is sawtooth. To make the field pattern similar to a sawtooth waveform, a multiharmonic buncher was adopted. The design process for the multiharmonic buncher includes a beam dynamics calculation and three-dimensional electromagnetic simulation. In addition to the system design for pulsed proton generation, a test bench with a microwave ion source is under preparation to test the performance of the system. The design study results concerning the pulsed proton beam generation and the test bench preparation with some preliminary test results are presented in this paper.