• Title/Summary/Keyword: serum Mg

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The Relationships of Serum Mg, Ca, Ca/Mg Ratio with Serum Lipid Profiles in College Women Living Choong-Nam Area (일부 충남지역 여대생의 혈청 마그네슘(Mg), 칼슘(Ca), 칼슘/마그네슘(Ca/Mg)비율과 혈청지질과의 상관관계 연구)

  • 김애정
    • Journal of the East Asian Society of Dietary Life
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    • v.8 no.4
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    • pp.379-387
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    • 1998
  • Magnesium(Mg) plays an important role in lipid metabolism and Mg deficiency but Ca sufficiency Increases serum cholesterol and triglyceride. The relationships of serum Mg, Ca, Ca/Mg ratio with lipids was examined in 79 female college students in Choong-Nam area. Subjects were divided into underweight, normal and overweight groups according to their BMI. The average age, body weight, height and BMI were 21.9yr, 55.9kg, 158.5cm and 22.62kg/$m^2$ respectively. Height was not different between groups. Serum cholesterol and LDL-cholesterol concentrations were significantly lower in the underweight group than other groups. BMI had positive correlations with LDL-cholesterol, atherogenic index (AI) and LDL-cholesterol/HDL-cholesterol ratio(LPH), and negative correlations with HDL-cholesterol/total cholesterol ratio. Serum minerals (serum Mg, Ca, Ca/Mg ratio) and serum lipid concentrations were not significantly different between groups. However, there was a tendency of increasing serum Mg level with increasing serum HDL-cholestrol, HDL-cholesterol/total cholesterol ratio and decreasing serum LDL-cholesterol, LPH, total cholesterol/HDL-cholesterol ratio(TPH) and AI. And there was a tendency of increasing serum Ca level with increasing serum HDL-cholesterol/total cholesterol ratio and decreasing serum triglyceride, LDL-cholesterol, LPH, TPH and AI. And there was a tendency of increasing serum Ca /Mg ratio level with decreasing triglyceride, serum LDL-cholesterol and TPH. This study was limited within serum levels of minerals (serum Mg, Ca and Ca/Mg ratio), serum lipids concerned with CHD, therefore I hope there will be wider efforts to consider about the dietary levels of minerals for presentation of the connection between dietary Mg, Ca and serum lipids.

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Changes of Electrolytes, Hematological Indices, and Cytokines following Dietary Magnesium Deficiency in Rats

  • Moon, Seong-Min
    • Biomedical Science Letters
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    • v.17 no.3
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    • pp.203-209
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    • 2011
  • Magnesium (Mg) plays an essential role in physiological and metabolic reactions. Recently, there has been an increased interest in the role of Mg deficiency, particularly the relationship between serum Mg value and inflammatory response. This study was designed to determine the relationship between serum Mg deficiency with inflammatory response, electrolytes and hematological alteration over long-term periods. Sixteen male Sprague-Dawley rats were divided into two groups: control (n=8), and Mg deficiency group (MgD group, n=8). Chow and normal water (tap water) were regularly provided to the control group and Mg-depleted chow and third distilled water were regularly provided for 60 days to the MgD group. Body weights, Serum Mg, $K^+$, inorganic phosphorus (IP) and total iron binding capacity (TIBC) levels in the MgD group were lower than those of the control group (P<0.05). Granulocyte fraction and MCV, RDW and PDW levels were higher, whereas lymphocyte fraction, erythrocyte, hemoglobin and MCHC levels were lower in the MgD group than in the control group (P<0.05). MCP-1 and TNF-${\alpha}$ levels in the MgD group were greater than those of the control group (P<0.05). In conclusion, the results of the present study suggest that Mg deficiency over a long-term period had not altered total leukocyte concentration in the blood, but had detrimental effects, including disturbances of electrolytes balance, disturbance of iron indices, potential anemia and elevation of pro-inflammatory cytokine. However, further studies should be performed to determine the relationship between serum Mg deficiency and major organ damage or alteration.

A Study on Mg Status in Adult Korean Rural Women on Self-Selected Diet (일상식이를 섭취하는 일부 한국 농촌여성의 Mg영양 상태에 관한 연구)

  • 승정자
    • Journal of Nutrition and Health
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    • v.23 no.1
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    • pp.25-36
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    • 1990
  • This study was carried out to investigate Mg status and the relationship between dietary Mg the blood pressure in 30 healthy women, 26 to 57 year of age, living in rural area of Korea. Dietary intake of the subjects on self-selected diet were recorded. Duplicated food sample and 24-hour urine samples were collected for 3 days. Mean daily dietary Mg intake levels were determined by chemical analysis of duplicated food samples and mean daily urinary Mg excretion was measured from urine samples. Fasting serum Mg levels of each subjects was measured on the 3rd day of the survey. The results were as following: 1) The mean daily intakes of energy, protein were 1770.36㎉ and 55.55g, respectively. Carbohydrare, fat and protein supplied 77.1%, 10.4% and 12.5% of total energy intake. 2) The dietary Mg showed positive correlations with carbohydrate(P<0.05), vitamin A and vitamin B2(P<0.01), energy, Ca, P, fiber, vitamin B1 and niacin(P<0.001), but negative correlation with SBP(P<0.05). 3) The daily mean intake of Mg was 259.07$\pm$74.54mg and the urinary excretion of Mg was 75.48$\pm$33.14mg which was 29.5% of the dietary intake of Mg. And there was no significance between the dietary intake and the urinary excretion of Mg. 4) The dietary fiber showed negative correlations with SBP and DBP(P<0.05). 5) The serum and urinary concentrations of Mg were normal range and the serum Mg showed negative correlation with dietary vitamin C(P<0.05, r=-0.3655). It was concluded that the dietary Mg level of Korean rural women consuming self-selected diets was lower than that of RDA of American women but higher than that of RDA of Canadian. And the dietary intake levels of Mg and fiber, which are contained mostly in cereals and vegetables are useful to prevent hypertention.

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Effect of Family Type on the Nutrient Intake and Nutritional Status in Elderly Women (가족형태에 따른 여자 노인의 영양소 섭취 및 영양 상태에 대한 연구)

  • 이현숙;장문정
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.4
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    • pp.934-941
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    • 1999
  • This study was performed to investigate the effect of family type on the nutrient intake and nutritional status in elderly women. Blood samples and anthropometric data of elderly women aged from 60 to 78 years were collected in 1996, who visited a health examination center in Seoul to screen their health status. They were divided into two groups by their family type, one was extended family(extended family elderly, n=37) and the other was independently living(independently living, n=29). Nutrients intake was measured by interview using a simplified questionaire. Albumin, cholesterol, triglyceride(TG), hemoglobin (Hb), hematocrit, Ca, Mg, and alkaline phosphatase activity of serum were analyzed. Intakes of energy, protein, carbohydrate, Fe, vitamin A, niacin, thiamin, riboflavin, and vitamin C were not different between the two groups. However, fat and Ca intakes were higher(p<0.05) in extended family elderly than indepen dently living elderly. There are no significant difference in hematocrit value and serum concentrations of Hb, TG, and Ca. Serum Mg and cholesterol levels tended to be higher in extended family elderly. However, serum albumin level was lower(p<0.05) in extended family elderly. These results show that the indepen dently living elderly women had intakes of daily energy, fat and Ca compared to the extended family elderly. Therefore, the nutritional education for the independently living elderly will be focused on the health risk resulted from less intakes of Ca and total energy.

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Magnesium Status in Children with Attention-Deficit/Hyperactivity Disorder and/or Autism Spectrum Disorder

  • Skalny, Anatoly V.;Mazaletskaya, Anna L.;Ajsuvakova, Olga P.;Bjorklund, Geir;Skalnaya, Margarita G.;Chernova, Lyubov N.;Skalny, Andrey A.;Tinkov, Alexey A.
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.31 no.1
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    • pp.41-45
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    • 2020
  • Objective: The objective of this study was to assess serum, hair, and urinary magnesium (Mg) levels in children with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and both ASD and ADHD to reveal potential interactive effects. Methods: A total of 148 boys aged 4-9 years old were enrolled in this study, including 44 children with ADHD, 40 pediatric patients with ASD, 32 patients with both ADHD and ASD, as well as 32 healthy neurotypical children. Hair, serum, and urinary Mg levels were assessed using inductively-coupled plasma mass spectrometry (ICP-MS). Laboratory quality control was performed using certified reference materials of human hair, plasma, and urine. Results: No significant group difference in serum Mg levels was observed. Mg content in hair was found to be reduced in children with ADHD and ADHD+ASD compared to that in healthy controls by 11% and 15%, respectively. Urinary Mg levels in children with ADHD+ASD exceeded the control, ADHD, and ASD values by 51, 76, and 65%, respectively. Factorial analysis revealed significant contribution of ADHD to hair and urinary Mg levels. Multiple regression analysis demonstrated that hair and urinary Mg levels were considered as significant predictors of neurodevelopmental disorder complexity. Conclusion: We propose that impaired Mg status may provide a link between ADHD and ASD.

Mineral Intakes and Serum Mineral Concentrations of the Pregnant and Lactating Women (임신$\cdot$수유부의 무기질 섭취와 혈청 무기질 함량에 관한 연구)

  • Kim Wooo Ju;Ahn Hong Seok;Chung Eun Jung
    • Korean Journal of Community Nutrition
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    • v.10 no.1
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    • pp.59-69
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    • 2005
  • The purpose of this study was to estimate the mineral intakes and serum mineral levels of pregnant and lactating women. The subjects consisted of 34 non-pregnant, 56 pregnant and 20 lactating women. Nutrients intakes were investigated by the 24-hr recall method, and serum major and trace minerals were analyzed by the ICP-spectrometry. Calcium (Ca) and zinc (Zn) intakes were observed lower than RDA especially for both pregnant and lactating women. Iron (Fe) intake of pregnant women was $85 - 139\%$ RDA through Fe supplementation, and that of lactating women was lower than RDA. Compared with non-pregnant women, the pregnant women had similar Ca intake and higher magnesium (Mg) intake. Comparing with the non-pregnant women, serum Ca level in pregnancy was lower, and that of lactating women was not significantly different. Serum phosphorus and Mg levels were not significantly different among the groups. Serum Fe level of pregnant and lactating women was lower than that of the non-pregnant women. Serum Zn level of pregnant women was lower than those in the lactating and non-pregnant women. Serum copper level decreased as the pregnancy progressed. Serum sodium (Na) level was higher in 2nd- and 3rd trimester and potassium (K) level was higher in 3rd trimester and lactating period than other groups. Na/K ratio was not significantly different among the groups. During all periods, there was no correlation between dietary intakes and serum levels in each minerals. Serum Ca level positively corrleated with serum Mg level, especially in 3rd trimester and lactating women. In general, serum mineral levels in pregnancy were changed compared to the levels in non-pregnancy and restored in lactation to the levels for non-pregnancy.

Analysis of Mineral Contents in Tissues and Bone Mineral Density of Rats (흰쥐의 조직 중 무기질 함량과 골밀도 분석)

  • Kim, Myung-Hee;Kim, Moo-Kyung;Lee, Jong-Wan;Kim, Mi-Hyun;Kang, Myung-Hwa;Choi, Mi-Kyeong
    • Reproductive and Developmental Biology
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    • v.34 no.3
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    • pp.123-126
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    • 2010
  • The purpose of present study was to analyze mineral contents in various tissues and investigate theirs relation with bone mineral density (BMD) in rats. Fifteen Sprague-Dawley rats were fed standard diet for 4 weeks. Body weight gain, feed intake, and feed efficiency ratio were 41.00 g/week, 171.15 g/week, and 0.24 respectively. Among 12 minerals in serum, Ca is the highest with 6.86 mg/dl. Serum Mg, Se, and Cu were 2.52 mg/dl, 0.23 mg/dl and 0.22 mg/dl respectively. Mg contents in liver, spleen, and kidney were $246.36\;{\mu}/g$, $105.01\;{\mu}/g$, and $273.38\;{\mu}/g$ respectively. Tibia contents of Ca, Mg, Zn, Fe and V were 194.91 mg/g, 23.10 mg/g, 0.60 mg/g, 0.35 mg/g and 0.14 mg/g respectively. BMDs of right tibia and spine were 122.04 mg/cm and $153.61\;mg/cm^2$. There were significantly positive correlations between tibia BMD and Se (p<0.05), tibia BMD and V (p<0.01), spinal BMD and V(p<0.05), respectively. It's expected that these results are used as a reference data in following study to elucidate physiological function of minerals.

Effect of Mineral Content of Orchardgrass (Dactylis glomerata L.) on Mineral Balance of Goats (오차드그라스 (Dactylis glomerata L.) 의 무기함량차에 따른 산양의 무기질 출납에 관한 연구)

  • Sang Deog A. Kim;Mitsuaki Ohshima;Shigekata Yoshida
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.13 no.3
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    • pp.184-189
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    • 1993
  • Orchardgrass(Dactylis glomerata L.) hays, which had been harvested in different seasons and grown with different levels of potassium (K)fertilizer, were fed to foats in metabolic cages in order to know the effect forage mineral content on mineral balance of goats. The K contents of the feed were 3.4, 4.9 and 5.8% and magnesium (Mg) contents were 0.26, 0.21 and 0.21% on a det matter(DM) basis in K-low, K0medium and K-high treatments, respectively. Urinary K excretion was significantly more on K-high than on K-low treatment. Faecal and urinary Mg excrerions on K-low were higher than those on K-medium and K-high feeds. And there was a tendency of positive relation between urinary Mg excretion and serum Mg concentrarion. Goats on K-high treatment seemed to drink more water and excrete more urine than those on the other feeds.

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Changes of Serum Mineral Concentrations in Horses during Exercise

  • Inoue, Y.;Osawa, T.;Matsui, A.;Asai, Y.;Murakami, Y.;Matsui, T.;Yano, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.4
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    • pp.531-536
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    • 2002
  • We investigated the exercise-induced changes in the serum concentration of several minerals in horses. Four welltrained Thoroughbred horses performed exercise for 5 d. The blood hemoglobin (Hb) concentration increased during exercise, recovered to the pre-exercise level immediately after cooling down and did not change again up till the end of experiment. The changes in serum zinc (Zn) and copper (Cu) concentrations were similar to those of blood Hb during the experiment. The serum magnesium (Mg), inorganic phosphorus (Pi) and iron (Fe) concentrations also increased during exercise. Though the serum Pi concentration recovered to the pre-exercise level immediately after the cooling down, it decreased further before the end of the experiment. The serum Mg concentration was lower immediately after cooling down than its pre-exercise level but gradually recovered from the temporal reduction. The recovery of the serum Fe concentration was delayed compared to that of other minerals and recovered 2 h after cooling down. The serum calcium (Ca) concentration did not change during exercise but rapidly decreased after cooling down. As a result, it was lower immediately after cooling down than its pre-exercise level. It recovered, however, to the pre-exercise level 2 h after cooling down. The temporal increase in the serum concentrations of all minerals except Ca is considered to result from hemoconcentration induced by exercise and the stable concentration of the serum Ca during exercise is possibly due to its strict regulation of homeostasis. These results indicate that the serum concentration of each mineral responds differently to exercise in horses, which may be due to the difference in metabolism among these minerals.