• Title, Summary, Keyword: serum protein

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Studies on the Concentration of Total Serum Protein of Milk Goat and Milk Cow Fed in Korea (유산양(乳山羊)과 유우(乳牛)의 혈청총단백량(血淸總蛋白量)에 관(關)하여)

  • Chung, Soon Tong;Cho, Hi Taek;Rhee, Yong So
    • Korean Journal of Veterinary Research
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    • v.8 no.2
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    • pp.65-67
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    • 1968
  • Observations were made to determine the effects of age and season upon the total serum protein values of milk goats(female) and milk cows fed in Korea. The results obtained in this work were summerized as follows; 1. In adults. the average concentrations of total serum protein of milk goats and milk cows were higher than in the younger, and were generally increased with the advance of age. The rate of increase in total serum protein value was more significant in the younger than that of adults. 2. The average concentrations of total serum protein of milk cows were significantly higher than those of milk goats. 3. Seasonal variation of total serum protein value was not observed in milk cows. 4. The average concentration of total serum protein of milk goat fed in Korea was much lower than that reported from the Occident, and this difference seemed to be influenced by the ration low in protein.

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The predictive value of serum myeloma protein in solitary plasmacytoma

  • Chang, Won Ick;Koh, Hyeon Kang;Yoon, Sung-Soo;Kim, Han-Soo;Eom, Keun-Yong;Kim, Il Han
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.129-137
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    • 2020
  • Purpose: To identify the clinical usefulness of serum M protein and to establish a rationale for regular follow-up with serum protein electrophoresis in solitary plasmacytoma. Materials and Methods: Sixty-nine patients with solitary plasmacytoma and solitary plasmacytoma with minimal marrow involvement according to the International Myeloma Working Group criteria were retrospectively reviewed. Results: At a median follow-up of 6.2 years, 5-year local control (LC), 5-year multiple myeloma-free survival (MMFS), 5-year failure-free survival (FFS), and 5-year overall survival (OS) were 82.6%, 44.1%, 41.8%, and 85.1%, respectively. Among the patients whose initial serum M protein was present or not evaluated, 37.3% of patients showed disappearance of serum M protein after various treatment. MMFS of these patients were comparable to non-secretory plasmacytoma with undetectable levels of M protein, and significantly better than patients with persistent M protein. Increase of serum M protein ≥0.1 g/dL was most predictive of treatment failure with area under the curve of 0.731. Conclusion: Patients who eventually showed persistence of serum M protein after treatment showed worse MMFS and FFS compared to those whose serum M protein disappeared or who had initially non-secretory disease. The increase of serum M protein level ≥0.1 g/dL from current nadir was predictive of treatment failure. Therefore, regular follow-up with serum M protein is highly recommended especially unless the patient had initially non-secretory disease.

Stidies on the Concentration of Total Serum Protein of Korean Cattle and Milk Cow Fed in Korea (한우(韓牛)와 유우(乳牛)의 혈청(血淸) 총단백량(總蛋白量)에 관(關)하여)

  • Chung, Soon Dong;Huh, Rin So;Rhee, Yong So
    • Korean Journal of Veterinary Research
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    • v.6 no.1
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    • pp.37-41
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    • 1966
  • Observations were made on the total serum protein values of 532 Korean cattles(341 females and 191 males and 191 males) and 90 milk cows in order to determine the effects of age, sex and nutritional status upon serum protein. Results obtained in this studies were summerized as follows; 1. The concentration of total serum protein was higher in the adult than in the younger and was generally increased with the advance of age in Korean cattle. The rate of increase in total serum protein content was more significant in the young than that of adult. 2. The average concentration of total serum protein of male did not differ significaltly from that of females in Korean cattle. 3. The concentration of total serum protein in milk cows were significaltly higher than that of Korean cattle cows and this difference seemed to be influenced by rations high in protein 4. A general tendency showed that the concentration of total serum protein was significaltly higher in the Korean cattle keeping with good nutritional status than that of poor nutritional status.

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Properties of Water Resistant Plywood made with Modified Serum Protein Adhesive (혈장변성접착제를 사용한 내수합판의 특성)

  • Kang, Seog-Goo;Lee, Hwa-Hyoung
    • Journal of the Korean Wood Science and Technology
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    • v.39 no.1
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    • pp.21-27
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    • 2011
  • This study was carried out to examine properties of water resistant plywood by using serum protein adhesive which is natural, environment-friendly and human-friendly. For the preparation of the serum protein adhesive, pig blood from slaughterhouse was centrifuged and serum was separated from corpuscles and concentrated to 30% by dry weight basis. This concentrated serum protein was modified with PF resin (50% NVC) with the ratio of 9 : 2.5. Plywood made by this modified serum protein gave 1.21 N/$mm^2$ of dry bonding strength, 0.80 N/$mm^2$ of wet boil bonding strength, 0% of cyclic delamination test value, and 0.025 ppm of HCHO emission, which met the excellent super $E_0$ grade and water resistant plywood.

Effects of Dietary Protein Levels on the Serum Lipids and Enzyme Activities of Ethanol-Administered Rats (에탄올을 투여한 흰쥐에서 식이 단백질 섭취 수준이 혈청중 지방 및 효소활성에 미치는 영향)

  • 고진복
    • Journal of Nutrition and Health
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    • v.25 no.7
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    • pp.578-585
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    • 1992
  • This study was undertaken to investigate effects of alcohol and dietary protein levels on serum lipids and enzyme activities in 15 week-old male rats given a normal diet. Rats were divided into 8 groups : control group (16% protein 16PC) and 8%(8PE) 16%(16PE) and 24% protein groups(24PE) to which was given 5% ethanol mixed into their drinking water after 4 weeks and 10 weeks. Body weight organ weight and various blood components were determined at 4 and 10 weeks. Body weight gain organ weight hemoglobin concentration and hematocrit value were not influenced by ethanol and dietary protein levels. The levels of total cholesterol HDL-cholesterol and phospholipid in serum were not affected by ethanol consumption. Serum triglyceride concen-trations after 10 weeks were significnatly increased ethanol-treated group compared with that of control group and the effect was greater in low protein group than control group. Serum ALP activity was significantly higher in 8PE group than other group but there was no influence by ethanol consumption.

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Effect of Dietary Protein and Magnesium Levels on Serum Lipid Contents and Enzyme Activities in Rats (단백질과 마그네슘 공급수준이 흰쥐의 혈청중 지질함량 및 효소활성에 미치는 영향)

  • 정복미
    • Journal of Nutrition and Health
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    • v.26 no.8
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    • pp.925-932
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    • 1993
  • To study the effects of dietary protein and magnesium level on serum lipid contents and enzyme activities, male Sprague-Dawley rats were divided into six groups. Six groups of animals were fed six experimental diets different with protein(8% and 20%) and magnesium levels (Mg-free, 400mg/kg diet and 800mg/kg diet). The serum lipid contents and enzyme activities of rats fed different dietary protein and magnesium levels were examined. Serum triglyceride contents was significantly decreased as the dietary magnesium level was increased. Serum phospholipid contents was significantly higher in magnesium deficient group than those in the other groups. Serum alkaline phosphatase activity was significantly decreased in magnesium dificient group compared with other groups, but serum glutamic oxaloacetic transaminase and glutamic pyruvic transaminase activities was significantly increased in magnesium dificient group than other groups. In conclusion, serum triglyceride contents in low protein level was remarkably decreased as the dietary magnesium level was increased.

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Chicken Insulin-Like Growth Factor-I Stimulates Protein Synthesis of Chicken Embryo Myoblasts Cultured in Serum-Free Medium

  • Kita, K.;Okumura, J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.1
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    • pp.17-20
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    • 2001
  • The effect of chicken IGF-I on protein synthesis of chicken embryo myoblasts cultured in serum-free medium was examined. When myoblasts were expanded to approximate 20-30% of well, the medium was changed to the serum-free medium including 0, 2, 20, 200 or 2000 ng/ml of recombinant chicken IGF-I. The culture medium including 10% fetal calf serum (FCS) was used as positive control. After 1 day of incubation, protein synthesis was measured by the incorporation of [$^3H$]-L-leucine. Thereafter cells were continued to incubate for further 18 hours, and the radioactivity in the protein was measured as an index of protein synthesis. The values for protein synthesis cultured in the serum-free medium without chicken IGF-I or with 2000 ng/ml of chicken IGF-I were the lowest. Protein synthesis was elevated with increasing chicken IGF-I concentration from 0 to 20 ng/ml. The values for protein synthesis in the 20 ng/ml and 200 ng/ml IGF-I groups were about half of that of the FCS group. The present study revealed that the potency of chicken IGF-I at the levels of 20 to 200 ng/ml to stimulate myoblast protein synthesis was about half of that of 10% FCS.

Effects of colostrum-conferred passive immunity on disease incidence in Korean native calves during the suckling period (한우 송아지의 초유섭취에 의한 수동면역이 포유기간 중의 질병발생에 미치는 영향)

  • Kim, Doo;Han, Hong-ryul
    • Korean Journal of Veterinary Research
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    • v.29 no.2
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    • pp.91-98
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    • 1989
  • The effects of the serum total protein and immunoglobulin levels of the colostrumconferred Korean native calves at 2 days of age on the disease incidence during the suckling period were studied. The results obtained were summerized as follows: 1. Serum total protein, total immunoglobulin, IgG, and IgM levels of 6 Korean native claves died from septicemia were lower than those of calves survived (p<0.05). 2. Korean native calves having low serum total protein and immunoglobulins were affected with diarrhea earlier in life, when compared with calves having high serum levels (p<0.05). 3. Korea native calves having low serum total protein were affected with bronchopneumonia earlier in life, when compared with calves having high serum levels (p<0.05). 4. Korean native calves having low serum neutralizing antibody titers to bovine viral diarrhea virus had high incidence rate of BVD, when compared with calves having high serum neutralizing antibody titers (p<0.05).

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Comparative study of serum levels of albumin and hs-CRPin hemodialysis patients according to protein intake levels (혈액투석 환자의 단백질 섭취량에 따른 혈중 albumin과 hs-CRP 농도의 비교 연구)

  • Lee, Ye Ji;Lee, Yeon Joo;Oh, Il Hwan;Lee, Chang Hwa;Lee, Sang Sun
    • Journal of Nutrition and Health
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    • v.46 no.6
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    • pp.521-530
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    • 2013
  • Protein-energy malnutrition, PEM, and increased hs-CRP level are considered to be associated with increased risk of cardiovascular disease (CVD) in hemodialysis (HD) patients. This is commonly referred to as the vicious circle of malnutrition-inflammation-atherosclerosis cardiovascular disease (MIA syndrome) in chronic kidney disease (CKD). Low protein intake can decrease the serum level of albumin and increase inflammational markers; further, both low serum albumin and high hs-CRP are independent risk factors for all-cause mortality in HD patients. The aim of this study is comparing the serum levels of albumin and hs-CRP in HD patients according to the protein intake levels. The total number of subjects was 60 hemodialysis patients; they were grouped by dietary protein intake: low protein intake group (LPI, protein intake < 1.0 g/kg IBW, 11 men and 19 women) and adequate protein intake group (API, protein intake ${\geq}$ 1.0g/kg IBW, 12 men and 18 women). Blood biochemical parameters, nutrient intake, and dietary behaviors were compared between the LPI and API groups. The LPI group showed a significantly lower serum level of albumin and higher serum level of hs-CRP than the API group (p < 0.05). The LPI group showed a significantly lower intake of most nutrients than the API group (p < 0.05). Index of Nutritional Quality of most nutrients of the LPI and API groups were lower than 1.0. Dietary protein intake was positively correlated with the serum level of albumin (r = 0.306, p < 0.05) and negatively correlated with the serum level of hs-CRP (r = -0.435, p < 0.01). The serum level of hs-CRP was negatively correlated with that of albumin (r = -0.393, p < 0.01). According to these result, serum albumin and hs-CRP in HD patients were influenced by the protein intake levels. To prevent MIA syndrome, it is necessary to improve nutritional status, especially in protein and energy.

Effect of Dietary Protein Level on Renal Function : Lipid and Eicosanoids Metabolism in Uninephrectomized Aging Model in Rats (식이 단백질 수준이 한쪽 신장을 절제한 흰쥐에서 혈청 지질 및 Eicosanoid 대사에 미치는 영향)

  • 이현숙
    • Journal of Nutrition and Health
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    • v.29 no.10
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    • pp.1072-1079
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    • 1996
  • This study was performed to elucidate the mechanism of dietary protein level on renal function through lipid and eicosanoids metabolism. Male rats of 337.8$\pm$5.7g body weight were undergone unilateral nephrectomy or sham-operation. The rats were divided into high protein(40% casein), normal protein(15% casein) and low protein(8% casein) diet groups and fed experimental diets ad libitum for 24 weeks. The results are summarized as follows. Serum total lipid, cholesterol and HDL-cholesterol of rats in 15% and 40% casein groups were higher than those of 8% casein group. But serum triglyceride was affected neither by uninephrectomy nor by dietary protein level. Serum thromboxane(TX) B2 and 6-keto prostaglandin F1$\alpha$ increased with increasing dietary protein level. Serum prostaglandin(PG) E2 was not affected by uninephrectomy nor by dietary protein level. Urinary PGE2 and TXB2 excretion tended to be lower in uninephrectomized groups. Renal tissue concentration of TXB2 was lower in uninephrectomized groups and in high protein group. These results suggest the possibility that the effects of dietary protein level on renal function could be due to changes in lipid and eicosanoids metabolism.

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