• Title, Summary, Keyword: therapeutic effects

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Therapeutical Effect with Trace Elements in Herbal Medicine (한약재내의 미량원소의 의의와 치료효과에 대한 고찰)

  • Park Hae-Mo;Lee Sun-Dong
    • Journal of Society of Preventive Korean Medicine
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    • v.4 no.2
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    • pp.25-56
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    • 2000
  • Trace element are involved in enzymatic activities, immunological reactions. physiological mechanisms. Deficiency in some trace elements, such as iron and iodine. is still an important health problem, The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. However, the importance of trace elements as chinese herbal constituents is not sufficiently appreciated by the oriental medical profession, although in recent years a significant increase of new finding on their essential character in chinese herbal medicine occurred. It is well known that herbal medicine contains a variety of trace elements which would show therapeutic effects with active components in herbal medicine . In china, recent work showed some positive correlation between trace element and traditional chinese medicine (TCM) in terms of therapeutic effects even if their role in therapeutic effects is still obscure. In korea, not much attention has been on the therapeutic importance of trace element contained in herbal medicine Here, the therapeutic effects of trace element in TCM were reviewed and summarized. 1. Iron, copper, zinc and manganese are mainly contained in TCM. In addtion, chromium, magnesium, molybdenum, nickel, alminium, cobalt, arsenic and selenium has been studied for their therapeutic effects 2. Zinc, is decreased in patients who have deficiency of kindney(腎虛) and chronic disease. Fe is decreased in patients who have deficiency of blood(血虛). However copper is increased in patients who have chronic disease and hepatic disease.3 Iron concentration is high in herbs used for tonifying and nourishing yin or blood(補陰補血藥) Zinc concentration is high also in herb used for tonifying kidiney and vital essence(補腎補精藥). In addition. copper concentration Is high in herb used for replenishing qi(補氣藥) 4 In herbal drugs, the therapeutic substances in TCM are not only organic but also inorganic. It seems that trace elements would be one of components in herb for its therapeutic effects. This indicates that therapeutic effects of TCM should be extended not only to herb itself, bur also to trace elements contained in herb.

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Mediating Effects of Hope and Therapeutic Relationship in the Relation between General Social Functions and Mental Health Recovery of Community People with Mental Illness (지역사회 정신장애인의 전반적 사회기능과 정신건강 회복 간의 관계에서 희망과 치료적 관계의 매개효과)

  • Shin, Sun Hwa;Hwang, Jung Hee
    • Journal of Korean Academy of Community Health Nursing
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    • v.30 no.1
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    • pp.69-78
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    • 2019
  • Purpose: This study tries to test mediating effects of hope and therapeutic relationship in the relation between general social functions and mental health recovery of community people with mental illness. Methods: This study was carried out in a cross-sectional research design. The participants included 217 people with mental illnesses who were enrolled at eight Mental Health Welfare Centers in the Gyeonggi Province. Data were collected from February to May, 2018. The collected data were analyzed using a regression analysis, and SPSS PROCESS macro was used to test the mediating effects. Results: This study analyzed the direct effects of general social functions on the hope, therapeutic relationship and mental health recovery. And general social functions had indirect effects on their mental health recovery via hope and therapeutic relationship. Both hope and therapeutic relationship had dual mediating effects in the influence of general social functions on mental health recovery. Conclusion: The role of hope and therapeutic relationship in the mental health recovery of community people with mental illness is important, and it is confirmed that hope is a powerful factor influencing mental health recovery.

A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system

  • Kim, Hee Jin;Kim, Pitna;Shin, Chan Young
    • Journal of Ginseng Research
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    • v.37 no.1
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    • pp.8-29
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    • 2013
  • Ginseng is one of the most widely used herbal medicines in human. Central nervous system (CNS) diseases are most widely investigated diseases among all others in respect to the ginseng's therapeutic effects. These include Alzheimer's disease, Parkinson's disease, cerebral ischemia, depression, and many other neurological disorders including neurodevelopmental disorders. Not only the various types of diseases but also the diverse array of target pathways or molecules ginseng exerts its effect on. These range, for example, from neuroprotection to the regulation of synaptic plasticity and from regulation of neuroinflammatory processes to the regulation of neurotransmitter release, too many to mention. In general, ginseng and even a single compound of ginsenoside produce its effects on multiple sites of action, which make it an ideal candidate to develop multi-target drugs. This is most important in CNS diseases where multiple of etiological and pathological targets working together to regulate the final pathophysiology of diseases. In this review, we tried to provide comprehensive information on the pharmacological and therapeutic effects of ginseng and ginsenosides on neurodegenerative and other neurological diseases. Side by side comparison of the therapeutic effects in various neurological disorders may widen our understanding of the therapeutic potential of ginseng in CNS diseases and the possibility to develop not only symptomatic drugs but also disease modifying reagents based on ginseng.

Therapeutic Effects of Electroacupuncture on Rumen Disease in Cattle (소의 제1위 질환에 대한 전침요법의 치료효과)

  • 남치주;서강문;장광호
    • Journal of Veterinary Clinics
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    • v.14 no.2
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    • pp.147-150
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    • 1997
  • This study was performed to evaluate the therapeutic effects of electroacupuncture on the ruminal disorders such as ruminal stony, ruminal impact, and ruminal tympany in dairy cattle. The therapeutic effects of electroacupuncture to ruminal stony and tympany were much better than those by medicaments and the combination of medicaments and electroacupuncture showed the most effective outcome of remedy. However, there was no difference in recovery rate of ruminal impact according to electroacupuncture, and medicaments alon, or combination of acupuncture and medicaments.

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Therapeutic potentials and untoward effects of Piper betle and its quid

  • Rai, Sujay;Mal, Mainak;Wahile, Atul;Mukherjee, Pulok K.
    • Advances in Traditional Medicine
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    • v.5 no.4
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    • pp.272-282
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    • 2005
  • Piper betle Linn. (PB), which belongs to the family Piperaceae, is used traditionally in many Asian countries for treatment of a variety of aliments. It has also been used in Ayurveda and Unani systems of medicine. PB leaves are also used as a masticatory in the form of quid. The basic preparation of PB leaves for chewing purposes (PB quid) is known as Paan in India. It is recommended in ancient scripture of Ayurveda and is closely associated with Indian culture. PB is reported to have several therapeutic potentials as well as to produce some untoward effects. The review deals with phytoconstituents present, therapeutic potentials and untoward effects of PB.

Effects of Therapeutic Exercise on Pain, Physical Function, and Magnetic Resonance Imaging Findings in a Patient with Multilevel Lumbar Disc Herniation: A Case Report

  • Kim, Ahram;Lee, Hoseong
    • Journal of International Academy of Physical Therapy Research
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    • v.10 no.1
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    • pp.1725-1733
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    • 2019
  • Background: In some clinical guidelines followed in clinical practice, nonsurgical treatments are recommended as the primary intervention for patients with lumbar disc herniation (LDH). However, the effect of a therapeutic exercise program based on stabilization of the lumbar spine for treatment of multilevel LDH has not been evaluated thoroughly. Objective: To investigate the effects of therapeutic exercise on pain, physical function, and magnetic resonance imaging (MRI) findings in a patient with multilevel LDH. Design: Case Report Methods: A 43-year-old female presented with low back pain, radicular pain and multilevel LDH (L3-L4, L4-L5, L5-S1). The therapeutic exercise program was conducted. in 40-min sessions, three times a week, for 12 weeks. Low back and radicular pain, lumbar disability, and physical function were measured before and after 6 and 12 weeks of the exercise program. MRI was performed before and after 12 weeks of the program. Results: After 6 and 12 weeks of the therapeutic exercise, low back and radicular pain and lumbar disability had decreased, and lumbar range of motion (ROM) was improved bilaterally, compared with the initial values. Also improved at 6 and 12 weeks were isometric lumbar strength and endurance, and the functional movement screen score. The size of disc herniations was decreased on MRI obtained after 12 weeks of therapeutic exercise than on the pre-exercise images. Conclusions: We observed that therapeutic exercise program improved spinal ROM, muscle strength, functional capacity, and size of disc herniation in LDH patient.

The Effects of Therapeutic Exercise on the Balance and Gait in Older Adults (치료적 운동이 노인의 균형과 보행에 미치는 효과)

  • Lee, Soo-Yeon;Son, Gil-Soo;Jeon, Hye-Jin;Lee, Moon-Hwan
    • The Journal of Korean Physical Therapy
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    • v.19 no.2
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    • pp.1-10
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    • 2007
  • Purpose: This study was conducted to investigate whether therapeutic exercise has effectiveness on the balance and gait in older adults. Methods: 30 patients were participated in this study. To evaluate the effects of therapeutic exercise, patients were evaluated by using One leg stand test which was static balance test, Berge balance test, Functional reach test and Get up and go test which was dynamic balance test. Finally Gait pattern were assessed by using 3-dimensional gait analysis system. The assessment parameters were evaluated before and after treatment. And we received a consent form from all patients. The data were analyzed by paired t-test for compare pre and after therapeutic exercise. Results: One leg stand test was significantly increased after than before therapeutic exercise. Get Up and Go test was significantly decreased after than before therapeutic exercise. Functional Reach test was significantly increased after than before therapeutic exercise. Burge Balance test was significantly increased after than before therapeutic exercise. Stride length was significantly increased after than before therapeutic exercise. Cadence was significantly increased after than before therapeutic exercise. Velocity was significantly increased after than before therapeutic exercise. Conclusion: We thought that therapeutic exercise that is mat exercise has effectiveness on the balance and gait in older adults.

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The Effects of Therapeutic Exercise on the Grip Strength of Chronic Neck Pain Patients (치료적 운동이 만성경부통증환자의 악력에 미치는 영향)

  • Jung, Yeon-Woo;Yoon, Se-Won;Lee, Jeong-Woo
    • Journal of the Korean Society of Physical Medicine
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    • v.4 no.2
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    • pp.73-78
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    • 2009
  • Purpose:The purpose of this study was to investigate effects of therapeutic exercise on the grip strength of chronic neck pain patients. Methods:Sixteen chronic neck pain patients were recruited this study(8 females. 8 males) from 21 to 30 years of age(mean aged 24.44). The experimental group received contraction-relax exercise for more than 3-5 times with therapeutic massage for 15minutes per day and three times a week during 5 weeks period. Grip strength was measured by Grip Strength Dynamometer(Model: T.K.K, 5101, Japan) at pre, 3weeks, 5weeks and follow-up 2weeks. Statistical analysis was used repeated ANOVA to know difference within period. Results:The grip strength was significantly increased within treatment period(p<.05), among them significantly increased within pre-treatment and follow-up 2weeks(p<.05). Conclusion:These results indicate that therapeutic exercise increased grip strength of chronic neck pain patients. Grip strength was more increased at follow-up 2weeks. In the future, we suggest that studies of therapeutic exercise regarding chronic neck pain patient be further studied and an appropriate therapeutic exercise will be indicated.

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A Study on the Development and Effects of an Educational Program for Ego Integrity of the Elderly through Therapeutic Recreation (치료레크레이션을 활용한 노인자아통합 교육프로그램 개발과 효과에 관한 연구)

  • Hong, Sook-Ja;Lee, Yeung-Eun
    • Korean Journal of Human Ecology
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    • v.17 no.4
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    • pp.623-630
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    • 2008
  • An educational program through therapeutic recreation was developed in order to analyze the effect of enhancement of ego integrity of the elderly. First of all, this study was designed to summarize the concepts of ego integrity and the effects of therapeutic recreation on the elderly and to identify elderly's educational needs of both educational methods and contents from the literature review. The above identified knowledge and information were applied to developing the educational program. The program was composed of 6 sessions with 17 old men and women focused on developing self acceptance using reminiscence on ego integrity through their whole life span and developing positive and active attitudes towards life. And enforcing and evaluation methods were also suggested. The results were as follows. This program showed the significant differences between post-test and pre-test scores in the scale of ego integrity of the elderly. In conclusion, educational program through therapeutic recreation employed for this study has significant effects of increasing ego integrity of the elderly.

Cardiac Regeneration with Human Pluripotent Stem Cell-Derived Cardiomyocytes

  • Park, Misun;Yoon, Young-sup
    • Korean Circulation Journal
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    • v.48 no.11
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    • pp.974-988
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    • 2018
  • Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which are collectively called pluripotent stem cells (PSCs), have emerged as a promising source for regenerative medicine. Particularly, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have shown robust potential for regenerating injured heart. Over the past two decades, protocols to differentiate hPSCs into CMs at high efficiency have been developed, opening the door for clinical application. Studies further demonstrated therapeutic effects of hPSC-CMs in small and large animal models and the underlying mechanisms of cardiac repair. However, gaps remain in explanations of the therapeutic effects of engrafted hPSC-CMs. In addition, bioengineering technologies improved survival and therapeutic effects of hPSC-CMs in vivo. While most of the original concerns associated with the use of hPSCs have been addressed, several issues remain to be resolved such as immaturity of transplanted cells, lack of electrical integration leading to arrhythmogenic risk, and tumorigenicity. Cell therapy with hPSC-CMs has shown great potential for biological therapy of injured heart; however, more studies are needed to ensure the therapeutic effects, underlying mechanisms, and safety, before this technology can be applied clinically.