• Title, Summary, Keyword: ultrasound-assisted extraction

Search Result 24, Processing Time 0.035 seconds

Comparison of Conventional Solvent Extraction, Microwave-Assisted Extraction, and Ultrasound-Assisted Extraction Methods for Paclitaxel Recovery from Biomass (바이오매스로부터 파클리탁셀 회수를 위한 전통적 용매 추출, 마이크로웨이브를 이용한 추출, 초음파를 이용한 추출 방법 비교)

  • Kim, Jin-Hyun
    • Korean Chemical Engineering Research
    • /
    • v.58 no.2
    • /
    • pp.273-279
    • /
    • 2020
  • In this study, conventional solvent extraction (CSE), microwave-assisted extraction (MAE), and ultrasound-assisted extraction (UAE) were compared for the recovery of paclitaxel from biomass. As a result of investigating the effect of the extraction solvent type (acetone, chloroform, ethanol, methanol, methylene chloride), methanol was the most suitable for all extraction methods. In the case of MAE and UAE using methanol, most of the paclitaxel (> 95%) was recovered by only one extraction. The recovery rate of paclitaxel increased with the increase of extraction temperature (25-45 ℃), microwave power (50-150 W), and ultrasonic power (180-380 W) for MAE and UAE. In addition, SEM analysis showed that the biomass surface structure was slightly corrugated in CSE, while in the MAE and UAE, it was very rough and destroyed by strong impact.

Optimization of ultrasound-assisted extraction of glycyrrhizic acid from licorice using response surface methodology

  • Jang, Seol;Lee, A. Yeong;Lee, A. Reum;Choi, Goya;Kim, Ho Kyoung
    • Integrative Medicine Research
    • /
    • v.6 no.4
    • /
    • pp.388-394
    • /
    • 2017
  • Background: The present study optimized ultrasound-assisted extraction conditions to maximize extraction yields of glycyrrhizic acid from licorice. Methods: The optimal extraction temperature ($X_1$), extraction time ($X_2$), and methanol concentration ($X_3$) were identified using response surface methodology (RSM). A central composite design (CCD) was used for experimental design and analysis of the results to obtain the optimal processing parameters. Results: Statistical analyses revealed that three variables and the quadratic of $X_1$, $X_2$, and $X_3$ had significant effects on the yields and were followed by significant interaction effects between the variables of $X_2$ and $X_3$ (p<0.01). A 3D response surface plot and contour plots derived from the mathematical models were applied to determine the optimal conditions. The optimum ultrasound-assisted extraction conditions were as follows: extraction temperature, $69^{\circ}C$; extraction time, 34?min; and methanol concentration, 57%. Under these conditions, the experimental yield of glycyrrhizic acid was 3.414%, which agreed closely with the predicted value (3.406%). Conclusion: The experimental values agreed with those predicted by RSM models, thus indicating the suitability of the model employed and the success of RSM in optimizing the extraction conditions.

Ultrasound-Assisted Liquid-Liquid Extraction for Recovery of Paclitaxel from Plant Cell Cultures (식물세포배양으로부터 파클리탁셀 회수를 위한 초음파를 이용한 액-액 추출)

  • Ha, Geon-Soo;Kim, Jin-Hyun
    • Korean Chemical Engineering Research
    • /
    • v.54 no.2
    • /
    • pp.229-233
    • /
    • 2016
  • In this study, an efficient ultrasound-assisted liquid-liquid extraction process was developed for recovering of paclitaxel from plant cell cultures. The optimal ultrasonic power and operating time were 250 W and 15 min at fixed ratio of bottom phase, methylene chloride to top phase, MeOH (25%, v/v). Under the optimal conditions developed in the present method, most of the paclitaxel (~92%) was recovered from crude extract by a single extraction step. Due to the synergistic effect of ultrasound by the addition of inorganic salt, an appropriate inorganic salt concentration and the ultrasonic power were found to be required for the effective recovery of paclitaxel using ultrasound-assisted liquid-liquid extraction.

Optimization of Ultrasound-Assisted Extraction for Antiradical Activities of Peel and Seed Extracts of Campbell Early Grapes

  • Ghafoor, Kashif;Choi, Yong Hee
    • Food Engineering Progress
    • /
    • v.13 no.1
    • /
    • pp.32-37
    • /
    • 2009
  • Central composite design was applied for the ultrasound-assisted extraction from peel and seed of Campbell Early grapes and the extraction processes were optimized for the antiradical activities of the extracts by using response surface methodology. Optimal conditions were 53.45% of ethanol concentration, 45.99${^{\circ}C}$ of extraction temperature and 23.93 min of extraction time for the maximum antiradical activity of grape peel extract (54.98%) and 53.14% of ethanol 56.03${^{\circ}C}$ of temperature and 29.03 min of time for maximum antiradical activity of grape seed extract (90.60%).

Optimization of Ultrasound-assisted Extraction of Phenolic Compounds from Salicornia herbacea Powder

  • Kim, Hui-Jeong;Lee, Jun-Ho
    • Preventive Nutrition and Food Science
    • /
    • v.14 no.2
    • /
    • pp.129-133
    • /
    • 2009
  • Salicornia herbacea is rich in natural minerals, dietary fibers, and potentially health-promoting phenolic compounds. In this paper, an experimental design was applied for the optimization of the ultrasound-assisted extraction of phenolic compounds from lyophilized Salicornia herbacea powder. The experiments were conducted in accordance with a five-level, three-variable central composite rotatable design (CCRD), and the effects of solvent concentration, extraction time, and extraction temperature were evaluated via response surface methodology (RSM). The optimal extraction conditions were as follows: ethanol concentration, 76.80%; extraction time, 20 min; and extraction temperature, $33.21^{\circ}C$; and the solvent concentration was the most significant parameter in this process, under which the predicted total phenolic content was 49.91 mg GAE/g sample.

Isolation of triterpenic acid-rich extracts from Hedyotis corymbosa using ultrasound-assisted supercritical carbon dioxide extraction and determination of their fictitious solubilities

  • Wei, Ming-Chi;Hong, Show-Jen;Yang, Yu-Chiao
    • Journal of Industrial and Engineering Chemistry
    • /
    • v.48
    • /
    • pp.202-211
    • /
    • 2017
  • The present study investigated a green ultrasound-assisted supercritical carbon dioxide ($USC-CO_2$) process for extracting oleanolic acid (OA) and ursolic acid (UA) from Hedyotis corymbosa. Chrastil, Bartle and Kumar and Johnston models were used to correlate the experimental fictitious solubility data. The overall average absolute relative deviation (AARD (%)) in solid solubility ranged from 3.632% to 6.529%, which indicates good agreement between the experimental fictitious solubility data and the modeled results. Using the correlation results, the total heat of solution and the enthalpies of vaporization and solvation for OA and UA in the $USC-CO_2$ extraction process were also estimated.

Ultrasound-Assisted Extraction of Canola Oil Using Supercritical Fluid Process (초음파가 적용된 초임계 유체 공정을 이용한 캐놀라오일 추출)

  • Hwang, Ah-Reum;Lim, Gio-Bin;Ryu, Jong-Hoon
    • KSBB Journal
    • /
    • v.25 no.5
    • /
    • pp.437-442
    • /
    • 2010
  • The objective of this study was to investigate the effect of ultrasound on the extraction of oil from canola seeds when supercritical carbon dioxide ($SCCO_2$) was used as an extraction solvent. The ultrasound-assisted $SCCO_2$ extraction were carried out while varying such operating parameters as particle size of crushed canola seed, flow rate of $SCCO_2$, aspect ratio of the extraction vessel, and ultrasound power. The extraction rate decreased with increasing particle size of samples, showing a maximun at a $CO_2$ flow rate of 6.2 L/min. Both the extraction rate and extraction yield increased with a decrease in the aspect ratio of the extraction vessel. For the ultrasoundassisted $SCCO_2$ extraction, the extraction yield was slightly increased when the $CO_2$ flow rate was below 6 mL/min with sample A and B.

Statistical Optimization of Antioxidant Extraction from Broussonetia kazinoki Using Ultrasound-assisted Extraction (초음파 추출공정을 이용한 닥나무로부터 항산화성분의 추출공정 최적화)

  • Lee, Seung Bum;Park, Bo Ra;Yoo, Bong-Ho
    • Applied Chemistry for Engineering
    • /
    • v.29 no.5
    • /
    • pp.565-570
    • /
    • 2018
  • In this study, the antioxidant was extracted from Broussonetia kazinokii using ultrasound-assisted extraction (UAE) and optimized by using a response surface methodology. The response value of the central composite design model establishes the extraction yield and the DPPH radical scavenging activity. The extraction time and temperature and volume ratio of ethanol/ultrapure water were selected as quantitative factors. When considering both the main and interaction effects, the factor having the greatest influence on the extraction yield and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was the volume ratio of ethanol/ultrapure water. The results of optimal extraction conditions were the extraction time (19.92 min), volume ratio of ethanol/ultrapure water (54.23%), and ultrasonic irradiation power (557.65 W). We could also obtained expected results of the yield = 38.93 wt% and DPPH radical scavenging activity = 55.33% under these conditions.

Optimization of ultrasound-assisted extraction of anthocyanins and phenolic compounds from campbell early grape using response surface methodology (반응표면분석법을 이용한 캠벨얼리 포도의 총 안토시아닌과 총 페놀의 초음파 추출조건 최적화)

  • Ryu, Dayeon;Koh, Eunmi
    • Korean Journal of Food Science and Technology
    • /
    • v.50 no.5
    • /
    • pp.474-479
    • /
    • 2018
  • In this study, ultrasound-assisted extraction conditions of total anthocyanins and total phenolic compounds from Campbell early grape (Vitis labruscana) were optimized via response surface methodology using a Box-Behnken design. Three independent variables, including solid-liquid ratio (1/30-1/50 g/mL), extraction time (2-10 min), and amplitude (20-100%), significantly affected total anthocyanin content. However, no significant effect of these variables was observed in the total phenolic compound content. The optimized extraction conditions were solid-liquid ratio of 1/48.13 g/mL, extraction time of 2 min, and amplitude of 20%. Under these conditions, the predicted values of total anthocyanins and total phenolic compounds were 94.96 and 1,661.16 mg/100 g dry weight (DW), respectively. The experimental values of total anthocyanins and total phenolic compounds were 88.25 and 1,554.37 mg/100 g DW, respectively, which is well matched with the predicted values within 7.5% difference.

Extraction of Useful component from Natural plants using Ultrasound system (초음파 시스템을 이용한 천연물로부터 유용성분의 추출)

  • Lee, Kwang-Jin;Um, Byung-Hun
    • KSBB Journal
    • /
    • v.23 no.2
    • /
    • pp.101-108
    • /
    • 2008
  • Ultrasound assisted extraction (UAE) process enhancement for food and allied industries are reported in this review. Recently ultrasound system has been used more frequently to extract drugs and natural substances. This modern emulsification, homogenization, particle size reduction and viscosity alteration methodologies require reliable tools that perform on a high level in terms of efficiency and reproducibility. Also, Ultrasound can enhance existing extraction processes and enable new commercial extraction opportunities and processes. Therefore, ultrasound technologies could have a strong presence in the future of the food industry.