Effects of Allii tuberosi Semen on the testicular function, the activity of catalase and peroxidase in male Rat

구子가 웅성 백서의 정소기능 및 catalase와 peroxidase의 활성에 미치는 영향

Park, Chang-Gun;Baek, Seung-Hee
박창건;백승희

  • Published : 20040000

Abstract

Objective:Allii tuberosi Semen has been used to treat impotence, nocturnal emission, enuresis, lumbago, leukorrhea etc. The aim of this study was to investigate the effects of Allii tuberosi Semen on testicular tissues and to evaluate Allii tuberosi Semen on treatment male infertility caused by azoospermia or oligozoospermia. Methods:To investigate the effects of Allii tuberosi Semen on testis and spermatogenesis, male rats were administered Allii tuberosi Semen extract for 28 days. We assayed total sperm concentration, morphologically normality, motility, activity of catalase and peroxidase from the testis in male rats at 28 days afterwards. Results:1)Total sperm concentration, morphologically normality and motility showed significant increase in male rat administered with Allii tuberosi Semen extract for 28 days. 2) It was observed that spermatogenesis has developed with vigor from testicular tissues in male rat administered with Allii tuberosi Semen. 3) Activity of peroxidase showed significant increase in male rat administered with Allii tuberosi Semen. Conclusion:These results indicate the effects of Allii tuberosi Semen on testicular function, activity of peroxidase in male rat. We suggested that Allii tuberosi Semen is an appropriate herbal medicine to treat medicaly male infertility caused by oligozoospermia or azoospermia.

Keywords

References

  1. 國譯編註醫學入門(卷四) v.4 李천
  2. Fam Plann Perspect v.30 no.1 Impaired fecundity in the United States, 1982-1995 Chandra, A.; Stephen, E.H.
  3. Demography v.22 no.3 Reproductive impairments in the United States, 1965-1982 Mosher, W.D.
  4. Int J Androl no.SUP.7 Towards more objectivity in diagnosis and management of male infertility Comhaire, F.H.;de Kretser, D.M.;Farley, T.M.(et al.)
  5. 대한산부인과학회 v.39 no.7 원인불명의 남성불임 환자에서 Pure Follicle Stimulating Hormone과 Human Chorionic Go4nadotropin을 이용한 전신적 치료에 관한 연구 김정훈;조윤경;목정은
  6. Br Med J. v.305 no.6854 Evidence for decreasing quality of semen during past 50 years Carlsen, E.;Giwercman, A.;Keiding, N.;Skakkebaek, N.E.
  7. Regulatory Toxicology and Pharmacology v.26 no.1 Hormonal disruptors and male infertility: are men at serious risk Lamb, D.J.
  8. Am J Hum Genet v.62 no.6 Male infertility and the genetics of spermatogenesis Okabe, M.;Ikawa, M.;Ashkenas, J.
  9. Fertil Steril v.26 no.4 The effect of orally administered androgens on sperm motility Brown, J.S.
  10. Fertil Steril v.54 no.4 Treatment of idiopathic testicular failure with high-dose testosterone undecanoate:a double-blind pilot study Comhaire, F.
  11. Fertil Steril v.55 no.3 Placebo-controlled trial of high-dose Mesterolone treatment of idiopathic male infertility Gerris, J.;Comhaire, F.;Hellemans, P.;Peeters, K.;Schoonjans, F.
  12. Fertil Steril v.29 no.4 Effect of clomiphene citrate on plasma levels of immunoreactive luteinizing hormone-releasing hormone, gonadotropin, and testosterone in normal subjects and in patients with idiopathic oligospermia Masala, A.;Delitala, G.;Alagna, S.;Devilla, L.;Lotti, G.
  13. 名醫別綠(輯校本) v.201 陶弘景
  14. 本草學 全國韓醫科大學 本草學敎授(編著)
  15. 中國藥材學 謝明村
  16. 中藥大辭典(上) 江蘇新醫學院
  17. 中華人民共和國藥典 中華人民共和國衛生部藥典委員會(編)
  18. 大韓本草學會誌. v.12 no.2 구子가 卵巢摘出로 誘發된 흰쥐의 骨多孔症에 미치는 影響(2) 徐富一;金先熙;卞晟僖;金美麗
  19. 大韓本草學會誌 v.14 no.2 구子의 抗酸化作用에 關한 硏究 朴涌基
  20. 泌尿器科學 金英均
  21. 中醫男科臨床治療學 冷方南
  22. Endocr Rev. v.22 no.2 chromosome microdeletions and alterations of spermatogenesis Foresta, C.;Moro, E.;Ferlin, A.Y .
  23. 諸病源候論校釋(上) 巢元方
  24. 備急千金要方 孫思邈
  25. 增補萬病回春(下) 공廷賢
  26. 六科證治準繩 王肯堂
  27. 婦人大全良方 陳自明
  28. 丹溪心法(附餘) 朱丹溪
  29. 實用中醫腎病學 張天
  30. 東國韓醫學硏究所論文集 v.3 金吉燮;徐雲敎;鄭智天
  31. 新藥品植物學 藥品植物學硏究會
  32. 原色韓國藥用植物圖鑑 陸昌洙
  33. 原色臨床本草學 辛民敎
  34. 臨床本草學 辛民敎
  35. 中醫百家藥論회萃 王輝武
  36. 中華臨床中藥學 雷載權(外)
  37. Fertil Steril v.28 no.12 Relation between indices of semen analysis and pregnancy rate in infertile couples Smith, K.D.;Rodriguez-Rigau, L.J.;Steinberger, E.
  38. Fertil Steril v.30 no.4 The duration of infertility: an important datum for the fertility prognosis of men with semen abnormalities Aafjes, J.H.;van der Vijver, J.C.;Schenck, P.E.
  39. Fertil Steril v.53 no.5 Effect of sperm morphology and motile sperm count on outcome of intrauterine insemination in oligozoospermia and/or asthenozoospermia Francavilla, F.;Romano, R.;Santucci, R.;Poccia, G.
  40. Fertil Steril v.61 no.2 Correlation of semen variables and pregnancy rates for donor insemination : a 15-year retrospective Johnston, R.C.;Kovacs, G.T.;Lording, D.H.;Baker, H.W.
  41. J In Vitro Fert Embryo Transf v.5 no.4 Failure of fertilization in in vitro fertilization: the occult male facto Oehninger, S.;Acosta, A.A.;Kruger, T.;Veeck, L.L.;Flood, J.;Jones, H.W. Jr.
  42. Science v.201 no.4359 The biology of oxygen radicals Fridovich, I.
  43. Biochem J. v.222 no.1 Free-radical mechanisms in tissue injury Slater, T.F.
  44. Nature v.262 no.5567 Oxygen and toxicity inhibition of amino acid biosynthesis Boehm, D.E.;Vincent, K.;Brown, O.R.
  45. Chest v.80 no.SUP. 1 DHydrogen peroxide mediates the toxic effect of oxygen radicals on human fibroblasts Simon, R.;Scoggin, C.;Patterson, D.
  46. Journal of Andrology v.16 no.6 Role of oxidative stress and antioxidants in male infertility Sikka, S.C.;Rajasekaran, M.;Hellstrom, W.J.