Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Clinical Study of Cream Containing Pueraria mirifia for Skin Elasticity

Pueraria mirifica 추출물 함유 화장품의 피부 탄력 임상 효능 평가

  • Kim Bora (R&D center of Skin Science and Cosmetics, Enprani Co., Ltd.) ;
  • Jung Sung Won (R&D center of Skin Science and Cosmetics, Enprani Co., Ltd.) ;
  • Lee Joo Dong (R&D center of Skin Science and Cosmetics, Enprani Co., Ltd.) ;
  • Ryoo Hee Chang (R&D center of Skin Science and Cosmetics, Enprani Co., Ltd.) ;
  • Cherdshewasart Wichai (Department of Biology, Faculty of Science, Chulalongkorn University)
  • 김보라 (엔프라니(주) 피부과학연구소) ;
  • 정성원 (엔프라니(주) 피부과학연구소) ;
  • 이주동 (엔프라니(주) 피부과학연구소) ;
  • 유희창 (엔프라니(주) 피부과학연구소) ;
  • Published : 2004.11.01
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Abstract

Recently, along with the remarkable increase in interest in natural products, the application of phytoestrogens in anti-aging products has become very important. In the focus, we developed Pueraria mirifica (PM), in this in vivo study on skin elasticity and wrinkles, and investigated the anti-aging properties. Thirty healthy women volunteers, between the ages of 30 and 60, applied the cream formula with $4\% Pueraria mirifica or placebo, on the face area twice a day for 16 weeks. The evaluation was made by silicon replica analysis, Cutometer SEM 575 and Comeometer followed by statistical treatment using the student's t-test. Results of skin elasticity measurement showed that topical application on the skin increased the total surface of skin elasticity in comparison with placebo group (p<0.05). However, PM cream does not have prominent effect on the depth of wrinkles and skin moisturization. This in vivo study demonstrates that, PM exhibits a significant effect on skin elasticity therefore, is of great interest in anti-aging and firmness skin care products.

최근에 천연성분의 화장품 응용에 대한 관심이 높아지고 식물에 함유하고 있는 피토에스트로겐(Phytoestrogen)의 항노화 물질 연구가 중요해지고 있다. 태국 식물 Pueraria mirifica 추출물을 $4\%$ 함유한 크림제제(PM 크림)를 추출물 성분이 제외된 플라시보 크림과 비교하여 총 30명 여성을 대상으로 16주간 임상시험을 수행하였다. 피부 모사판을 제작하여 주름 측정을 하였고, 피부 탄력과 보습을 기기 평가하였다. 특히 피부 탄력도는 placebo 크림 사용군 대비 추출물 함유 크림 사용군이 통계적으로 유의하게 탄력도가 증가하였다. 주름이나 보습평가는 특이할 만한 결과를 나타내지는 못했다. Pueraria mirifiaca는 피부 탄력 개선을 주는 항노화 화장품 개발에 응용될 수 있을 것이라 기대된다.

Keywords

References

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