Clinical Efficacy of External Preparation Containing Herbal Extracts m Atopic Dermatitis Patients

아토피 피부염 환자에서 한방 추출물이 포함된 외용제품에 대한 임상 효과

  • 김정태 (대전대학교 한의과대학 안이비인후피부과학교실) ;
  • 정현아 (대전대학교 한의과대학 안이비인후피부과학교실) ;
  • 노석선 (대전대학교 한의과대학 안이비인후피부과학교실) ;
  • 김창훈 (대전대학교 한의과대학 안이비인후피부과학교실)
  • Published : 2007.08.25

Abstract

Background : Atopic dermatitis is a chronic and recurrent allergy eczema, called as 'Tae-yul'. It is a characteristic dermatitis, diagnosed from baby to adult, that carries severe itching. Objectivd : The aim of this trial is to examine the effect and safety of Medibebe in patients with atopic dermatitis. Methods : We made a comparison between before and after the use this product. Volunteers who satisfied the requirements were enrolled in the study. Degrees of severity of atopic dermatitis were measured by SCORAD index. Results : After 4 weeks' use of Medibebe, SCORAD index showed a decrease of $20.0{\pm}10.2$(95% C.I: 17.1-22.9) compared with when it was not applied, which is a statistically meaningful change(p-value<0.0001). Subjective pruritus and Sleeping loss reported after both 2 and 4 weeks' use of Medibebe decreased in a statistically meaningful way(p-value<0.0001) compared with before the application. but, 2 cases out of all 50 subjects for the clinical trial were excluded on the way. Conclusion : As a result of applying the 4 items of Medibebe(cream, lotion, soap, and body cleanser) to patients with atopic dermatitis and watching the progress, it is concluded and considered that these cleansing and moisturizing products can be used by atopic patients safely and effectively with almost no side-effect.

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