Proceedings of the KOSOMBE Conference (대한의용생체공학회:학술대회논문집)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Preparation of blood-compatible polyurethanes by surface modification

표면개질에 의한 혈액적합성 폴리우레탄의 제조

  • 한동근 (한국과학기술원 고분자화학연구실) ;
  • 정서영 (한국과학기술원 고분자화학연구실) ;
  • 김영하 (한국과학기술원 고분자화학연구실) ;
  • 민병구 (서울대학교 의과대학 의공학과)
  • Published : 1990.11.16
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Abstract

To develop better blood compatibility of commercial polyurethane(PU), PU surface was chemically modified wi th a hydrophobic perfluorocarhon or a hydrophilic polyethylene oxide(PEO) and/or sulfonated groups, respectively. The water contact angle of modified PUs varied from $110^{\circ}$ to $0^{\circ}$. All the modified PUs were more blood compatible than untreated PU. In particular, PEO-sulfonate grafted PUs showed a very enhanced antithrombogenicity due to the synergistic effect of PEO and $SO_3$ groups. Therefore more hydrophobic and hydrophilic PU surfaces are promising for improving the blood compatibility.

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