Optical-Electronic Method for Statistical Evaluation of Human Corneal Endothelial Patterns

Human Corneal Endothelial 패턴의 통계적 분석을 위한 광전자적 방법

Hybrid optical-electronic procedures are introduced for the automated estimation of cell parameters (e.g., size, size variation, and shape). Two different optical Fourier analysis procedures are applied to high contrast cell boundary patterns obtained from specular micrographs of the endothelial layer. In one case, a large number of cell patterns are illuminated to extract average cell size information. Once the average cell size information has been obtained, individual cells are illuminated to extract shape information.