Proceedings of the Ginseng society Conference (고려인삼학회:학술대회논문집)

The Korean Society of Ginseng (고려인삼학회)
권호 표지

STUDIES ON BIOLOGICALLY ACTIVE SUBSTANCES IN NON-SAPONIN FRACTION OF KOREAN RED GINSENG

  • Okuda Hiromichi (Department of Medical Biochemistry School of Midicine, Ehime University) ;
  • Zheng Yinan (Department of Medical Biochemistry School of Midicine, Ehime University) ;
  • Matsuura Yukinaga (Department of Medical Biochemistry School of Midicine, Ehime University) ;
  • Takaku Takeshi (Central Research Laboratory, School of Medicine, Ehime University) ;
  • Kameda Kenji (Central Research Laboratory, School of Medicine, Ehime University)
  • Published : 1993.09.01
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Abstract

Acidic polysaccharide from Korean red ginseng was found to inhibit pancreatic lipase activity and cause reduction of plasma triglyceride level after oral administration of corn oil emulsion to rats. Thus acidic polysaccharide may reduce plasma triglyceride through its inhibitory action on pancreatic lipase and successive inhibition of intestinal absorption of fat due to reduction of lipolysis. In the course of this experiment, we found an unknown ninhydrin positive substance in Korean red ginseng. The unknown substance was identified to be arginyl-fructosyl glucose(Arg - Fru - Glc). Coment of this new compound was $5.37\%$ in Korean red ginseng powder. Sucrase and maltase activities in mucous layer of rat jejunum were found to be inhibited by Arg-Fru-Glc. Physiological significance of the new compound was discussed based on these experimental results.

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