Lead Effects among Secondary Lead Smelter Workers with Blood Lead Levels below $80{\mu}g/100\;ml$

  • Lilis Ruth (Environmental Sciences Laboratory Mount Sinai School of Medicine City University of New York) ;
  • Fischbein Alf (Environmental Sciences Laboratory Mount Sinai School of Medicine City University of New York) ;
  • Diamond Sidney (Environmental Sciences Laboratory Mount Sinai School of Medicine City University of New York) ;
  • Anderson Henry A. (Environmental Sciences Laboratory Mount Sinai School of Medicine City University of New York) ;
  • Selikoff Irving J. (Environmental Sciences Laboratory Mount Sinai School of Medicine City University of New York) ;
  • Blumberg William E. (Biophysics Research Department Bell Labora tories Murray Hill, New Jersey) ;
  • Eisinger Josef (Biophysics Research Department Bell Labora tories Murray Hill, New Jersey)
  • Published : 1994.02.01

Abstract

A subgroup or workers from a secondary lead smelter was defined to include those with blood lead levels not exceeding $80{\mu}g/100\;ml$ and with no pest history of elevated blood lead. Central nervous system symptoms (tiredness, sleeplessness, irritability, headache) were reported by 55% of the group and muscle and joint pain by 39%. Zinc proteporphyrin (ZPP) levels were elevated in 71% or cases. Low hemoglobin levels (less than 14 gm/l00 ml) were round in more than a third of the workers. While BUN and creatinine were mostly in the normal range, there - nevertheless n correlation between ZPP and both BUN and creatinine. Reduced nerve-conduction velocities were present in 25% or the group; this was not significantly different from findings in Ii control group. The data indicate that n blood level of $80{\mu}g/100\;ml$ is an inappropriate biological guide in the prevention or lead disease.

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