Determination of Total Hemoglobin in Whole Blood by Spectroscopy

분광학적 방법을 이용한 전혈내의 총 혈색소량 결정

  • Kim, Y.J. (Biomedical Engineering Research Center, Samsung Biomedical Research Institute) ;
  • Yoon, G. (Biomedical Engineering Research Center, Samsung Biomedical Research Institute) ;
  • Kim, W.K. (Biomedical Engineering Research Center, Samsung Biomedical Research Institute) ;
  • Kim, J.W. (Department of Clinical Pathology, Samsung Medical Center)
  • 김연주 (삼성생명과학연구소 임상의공학센타) ;
  • 윤길원 (삼성생명과학연구소 임상의공학센타) ;
  • 김원기 (삼성생명과학연구소 임상의공학센타) ;
  • 김종원 (삼성의료원 임상병리과)
  • Published : 1996.11.15

Abstract

Noninvasive monitoring of total Hemoglobin value is feasible with the use of spectroscopic measurements. As a step toward tile final goal of the development of a noninvasive monitor, the spectra$(400{\sim}800mm)$of EDTA whole blood were obtained along with reference total Hemoglobin values. Under the same condition water spectrum was generated. It was subtracted from each blood sample, and then tile first derivative of each subtracted data was taken by 'approximated first derivative algorithm' with gap (1,6,10,20nm). The correlation was obtained between total Hemoglobin and first valley wavelength of first derivative spectrum (sample number: 93).

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