Evaluation of Sulfite Solution to Predict Oxygen Transfer Rates in Artificial Lung

인공폐에서의 산소전달 속도를 예측하기 위한 아황산용액의 평가

  • Lee, S.C. (Department of Petrochemical Engineering, Hanlyo University) ;
  • Kim, K.B. (School of Chemical Engineering and Technology, College of Engineering, Chonbuk National University) ;
  • Jheong, G.R. (School of Chemical Engineering and Technology, College of Engineering, Chonbuk National University)
  • 이삼철 (한려대학교 석유화학공학과) ;
  • 김기범 (전북대학교 공과대학 화학공학부) ;
  • 정경락 (전북대학교 공과대학 화학공학부)
  • Published : 1998.11.20

Abstract

The kinetics of sulfite oxidation must be fast and the concentration of sulfite must be low to emulate oxygen uptake by blood. The kinetics were studied yielding a first order rate constant in sulfile, zero order in oxygen. Limitations of the technique were evaluated using the experimental rate constant and an adaptation of Lightfoot's approximation, while the reaction of hemoglobin is reversible and essentially instantaneous, that for sulfite is irreversible and finite. Thus if the approach to saturations not monotonic or if the mass transfer resistance is significantly lowered, e. g. when blood film thicknesses are thinner than a few hundred microns, deviations may occur.

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