Difference of total activation depends on stimulation paradigm at motor and visual cortices and cerebellum

운동과 시각 피질, 소뇌에서 자극변화에 따른 총활성화의 차이

  • Chung, S.C. (Dept. of Electrical Engineering, KAIST) ;
  • Song, I.C. (Institute of Radiation Medicine, Seoul National University) ;
  • Chang, K.H. (Dept. of Diagnostic Radiology, Seoul National University College of Medicine) ;
  • Yu, B.K. (Dept. of Diagnostic Radiology, Seoul National University College of Medicine) ;
  • Mun, C.W. (Medical Electronics Team, Samsung Advanced Institute of Technology) ;
  • Cho, Z.H. (Dept. of Radiological Sciences, University of California )
  • 정순철 (한국과학기술원 전기및전자공학과) ;
  • 송인찬 (서울대학교 의학연구원 방사선의학연구소) ;
  • 장기현 (서울대학교 의과대학 방사선과학교실) ;
  • 유병기 (서울대학교 의과대학 방사선과학교실) ;
  • 문치웅 (삼성 종합기술원 의료기기 연구팀) ;
  • 조장희 (캘리포니아 어바인대학 방사선과학과)
  • Published : 1998.11.20

Abstract

Purpose To investigate the difference of total activation in visual area, motor area, and cerebellum according to the stimulation paradigm. Materials and Methods Functional MR imaging was performed in 5 healthy volunteers with visual and motor activity using EPI technique. LED and Checker-Board stimulation were performed for visual activity. Thumb motion and Finger tapping were performed for motor and cerebellum activity. Time course data was obtained by calculating the total activation which was defined as the number of activated pixels x averaged pixel intensity. Results In the case of visual activity with LED stimulation, we found increased total activity of more than 100% compared with Checker-Board stimulation. In the case of motor area and cerebellum with Finger tapping stimulation, we found increased total activity of more than 100% and 150%, respectively compared with Thumb motion stimulation.

Keywords