A comparison of functional MRI and MRSI on occipital cortex by visual stimulation

시각자극에 의한 후두엽 피질에서의 기능적 자기공명영상법과 양성자 대사물질영상의 비교

  • Kim, T. (Department of Biomedical Engineering, College of Medicine, Catholic University) ;
  • Suh, T.S. (Department of Biomedical Engineering, College of Medicine, Catholic University) ;
  • Choe, B.Y. (Department of Biomedical Engineering, College of Medicine, Catholic University) ;
  • Shinn, K.S. (Department of Biomedical Engineering, College of Medicine, Catholic University)
  • 김태 (가톨릭대학교 의과대학 의공학교실) ;
  • 서태석 (가톨릭대학교 의과대학 의공학교실) ;
  • 최보영 (가톨릭대학교 의과대학 의공학교실) ;
  • 신경섭 (가톨릭대학교 의과대학 의공학교실)
  • Published : 1998.11.20

Abstract

The purpose of the study was aimed to evaluate the BOLD contrast fMRI in occipital lobe and compare this imaging with metabolite changes based on $^1H$ MRS and MRSI before and after visual stimulation. As a result, the activation map were sucessfully produced by thresholding with minimum cross-correlate value of 0.45. In MRS, NAA/Cr ratio is almost same. however, latate was elevated almost 9 times higher than before activation. Lactate metabolic images were consistent with the BOLD effect map. The BOLD contrast fMRI is not enough to detect the activation area in human brain. so, the other modality was required such as lactate metabolic map.

Keywords