In seismic analysis, there are two main ways - uniform load method and dynamic analysis, dynamic analysis can be divided into response spectrum analysis and time history analysis. In case of which get the complexion of the vibration with 3-axis of coordinate direction in each mode of free vibration mode happened owing to complication of the shape, 3-dimensional dynamic analysis is recommended to perform as multi-mode spectral analysis in standard specification for highway bridge. The purpose of this study is to understand the dynamic behavior by performing multi-mode seismic analysis according to responses analysis and time history anal)'sis in using record of earthquake. In accordance with the criterion of seismic design as defined in standard specification for highway bridge by using modified records of the El Centre and Coyote Lake earthquake, response spectrum was constructed by using the tripartite logarithmic plot. The 3-span continuous space truss bridge was selected as model of numerical analysis. As the result performed time history analysis and analysis of response spectrum for the model of numerical analysis, the result of time history analysis was slightly larger than that of response spectrum analysis. This coincide with the tendency of the result came from the analysis when using a jagged response spectrum analysis, This coincide with the tendency of the result came from the analysis when using a jagged response spectrum for a single excitation. In the Process of performing these two analysis. response spectrum analysis is more effective than time history analysis in saving times in analyzing data.