Effect of introduction of fumarase on the production of succinic acid

  • 홍순호 (한국과학기술원 화학공학과 및 생물공정연구센터) ;
  • 이상엽 (한국과학기술원 화학공학과 및 생물공정연구센터)
  • Published : 2000.04.08

Abstract

The fumB gene encoding anaerobic fumarase of Escherichia coli XL1-Blue was introduced to solve the malic acid accumulation problem. When NZN111 harboring pTrcMLFu was cultured, 7 g/L of succinic acid was produced and malic acid was not accumulated.

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