Proceedings of the Korean Society of Applied Pharmacology (한국응용약물학회:학술대회논문집)

The Korean Society of Applied Pharmacology (한국응용약물학회)
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The Anti-inflammatory Action and Effect on Collagen-induced Arthritis in DBA/1J Mice of Head of Panax ginseng

인삼노두의 소염작용 및 DBA/1J 마우스에서의 콜라겐유발 관절염에 대한 효과

  • 정춘식 (덕성여자대학교 약학대학) ;
  • 정기화 (덕성여자대학교 약학대학) ;
  • 조소연 (서울대학교 천연물과학연구소) ;
  • 김영식 (서울대학교 천연물과학연구소) ;
  • 이은방 (서울대학교 천연물과학연구소) ;
  • 이대위 (서울대학교 천연물과학연구소) ;
  • 현진이 (서울대학교 천연물과학연구소)
  • Published : 2001.11.01
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Abstract

Head of Panax ginseng indicates its growth number of years and it has been widely used for supplying energy to weak person. However, the underlying mechanisms are not sufficiently reported. Thus, we inclined to study head of Panax ginseng in rheumatoid arthritis and inflammation. Rheumatoid arthritis (RA), an organ-specific inflammatory disease of human, is characterized by a chronic and destructive inflammatory reaction and possibly autoimmune in etiology. It is occurred when the synobial membranes of joints and many other tissues of the body is attacked which induces significant health problem in terms of numbers of sufferers (U.S. incidence 23.7/100,000), and the synobial inflammatory is dominated by activated macrophage.

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