Evaluation of Cerebral Cortices Associated with Sexual Arousal in Healthy Male Using BOLD-based Functional MRI

  • Kim, Hyung-Joong (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Seo, Jeong-Jin (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Kang, Heoung-Keun (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Jeong, Gwang-Woo (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Park, Jin-Gyoon (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Jeong, Yong-Yeon (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Chung, Tae-Woong (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Woong Yoon (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School) ;
  • Park, Kwang-Sung (Departments of Radiology, Chonnam National University Medical School, Departments of Urology, Chonnam National University Medical School)
  • Published : 2001.11.01

Abstract

Purpose: The purpose of this study was to identify cerebral cortices related with sexual arousal fro visual sexual stimulation in healthy males using BOLD-based functional MR imaging Method: Sixteen male volunteers with sexually potent(mean age:24) were examined for thi study. Functional MRI was performed on a 1.5T MR scanner(GE Signa Horizon) with birdcage-type head coil. In this study, blood oxygenation level dependent(BOLD) technique was utilized to create fMR image reflecting local brain activities. The BOLD-based fMRI d were obtained from 7 oblique planes using gradient-echo EPI with $90^{\circ}$flip angle, 50ms TE 6000ms TR, $26cm{\times}26$ cm FOV, $128{\times}128$ matrix, and 10mm slice thickness. The sexual stimulation paradigm consisted of two alternating periods of rest and activati and it began with a 1 minute rest, followed by a 2 minute stimulation by a documentary a erotic video film. Brain activation maps were generated by cross-correlation of imag acquired during rest and activation periods. The index of activation was used to compare t number of pixels activated by each task in each volunteer, where the significance of th differences was evaluated by using Students t-test.

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