THE DIFFERENCES IN REGULATION OF COX-2 EXPRESSION BETWEEN ESTROGEN AND ISOFLAVONES

  • Shin, Jang-In (Applied Sciences, College of Natural Sciences, Hannam University) ;
  • Kim, Jung-Hwan (College of Pharmacy, Seoul National University) ;
  • Park, Ock-Jin (Applied Sciences, College of Natural Sciences, Hannam University)
  • Published : 2001.05.01

Abstract

Estrogen is known to exert potent vasodilating effects accompanied with an elevation of cyclooxygenase-2 (COX -2) expression. Structurally similar compounds, isoflavones, have shown in our previous study that they stimulate COX-2 of the heart of animals fed soy isoflavones.(omitted)

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