Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2001.10a
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- Pages.169-169
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- 2001
SINGLE OR FOUR-WEEK REPEATED INTRAVENOUS TOXICITY STUDIES OF A NEW CEPHALOSPORIN ANTffiIOTIC AGENT, IDC-7181 IN RATS
- Zhang, Hu-Song (College of Veterinary Medicine, Chungbuk National University) ;
- Huang, Zai-Zhi (College of Veterinary Medicine, Chungbuk National University) ;
- Jung, Eun-Yong (College of Veterinary Medicine, Chungbuk National University) ;
- Jung, Seong-Eui (College of Veterinary Medicine, Chungbuk National University) ;
- Lim, Kwang-Hyun (College of Veterinary Medicine, Chungbuk National University) ;
- In, Chang-Hoon (College of Veterinary Medicine, Chungbuk National University) ;
- Kim, Dae-Joong (College of Veterinary Medicine, Chungbuk National University) ;
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Nam, Sang-Yoon
(College of Veterinary Medicine, Chungbuk National University)
;
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Kang, Jong-Koo
(College of Veterinary Medicine, Chungbuk National University)
- Published : 2001.10.01
Abstract
This study was designed to evaluate an acute and subacute intravenous dose toxicity of a new cephalosporin antibiotic agent, IDC-7181 in 7-week-old Sprague-Dawley rats. IDC-7181 was intravenously injected to rats at dose levels of 0, 3.2, 16, 80, 400 and 2, 000 mg/kg/day for single dose toxicity study and at dose levels of 0, 10, 50 and 250 mg/kg/day for 4 week-repeated dose toxicity study. All rats survived throughout the study periods.(omitted)
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