Estrogenic Activity Assessment of Alkylphenolic chemicals using in vitro assays : III. Rcombinant Yeast Transcriptional Assay

  • Park, Hyo-Joung (Toxicology Laboratory, Korea Institute of Science and Technology) ;
  • Lee, Ho-Ja (Department of Biology, Kyunghee University) ;
  • Park, Kyunghee (National Institute of Environmental Researc) ;
  • Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science and Technology)
  • Published : 2001.05.01

Abstract

There is a concern that chemicals in our environment are affecting human health by disrupting a normal endocrine function. Much of the concern has focused on chemicals that can interact directly with steroid hormone receptors. The ability of certain man-made chemicals to mimic the effects of natural steroid hormones and their potential to disrupt the delicate balance of the endocrine system in animals are of increasing concern. (omitted)

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