한국생물공학회:학술대회논문집

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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The anti-inflammatory efficacy test of Cosmetic Ingredients Using Bioartificial Skin Model

  • 이종원 (동국대학교 화학공학과 조직공학연구실) ;
  • 양은경 ((주) 바이오랜드 생명공학연구소) ;
  • 고강일 ((주) 바이오랜드 생명공학연구소) ;
  • 김기호 ((주) 바이오랜드 생명공학연구소) ;
  • 박정극 (동국대학교 화학공학과 조직공학연구실)
  • Published : 2001.11.07
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Abstract

In this study. an efficacy study of Portulaca Extract (PE) and ${\beta}$ -glucan. candidates for cosmetic additives. was pedormed using artificial skin model (AS). The AS consists of collagen gel matrix populated by ATCC human skin fibroblast cell line that is overlaid with epidermal human skin keratinocyte cell line. Cytotoxicity and anti - inflammatory activity of PE and ${\beta}$ -glucan were assessed using monolayer and AS models by measuring cell viability and the secretion of interleukin -1 ${\alpha}$.

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