Measurement of Biomechanical Property of Chondrocyte

연골세포의 기계적 물성치 측정

A cyto-indentation technique was used to obtain the biomechanical compressive compliance property of an chondrocyte cell attached to glass surface, which was tried to generate joint cartilage by tissue engineering. Piezo-transducer system and dual photo-diode system were used to conduct mechanical indentation through displacement-controlled testing and the measurement of corresponding cell reaction force. The Poisson's ratio of 0.37 was quoted from other report. The compressive compliance of chondrocyte, that was determined by elastic contact theory, was 1.38${\pm}$0.057 kPa. This value is 30% higher than that of MG63 osteoblast-like cell. The cyto-indentation technique employed in this study is so precise that it can quantify the biomechanical property of single cell.