Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.11b
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- Pages.201-201
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- 2002
Investigation of gene expression of GX-12, a new DNA vaccine for HIV infection, in reproductive organs in SD rats
- Kang, Kyung-Koo (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Park, Min-Seul (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Ahn, Kook-Jun (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Baik, Dae-Hyun (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Sohn, Yong-Sung (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Lee, Dong-Sup (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Park, Jae-Hun (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
-
Ahn, Byoung-Ok
(Research Laboratories, Dong-A Pharm. Co. Ltd.)
;
- Kim, Won-Bae (Research Laboratories, Dong-A Pharm. Co. Ltd.)
- Published : 2002.11.01
Abstract
GX-12 is a naked DNA vaccine developed by Dong-A pharmaceutical company for the treatment of mv infection. GX-12 consists of four separate plasmids. This study was performed to evaluate the biodistribution and expression of GX-12 mRNA in gonadal tissues, and to investigate the histopathological changes in rats after repeated intramuscular injection.(omitted)