Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Microarray Analysis of Differential Gene Expression in Alcohol-Exposed Post Implantation Embryos

  • Kim, So-Hee (National Institute of Toxicological Research, Korea FDA) ;
  • Rhee, Gyu-Seek (National Institute of Toxicological Research, Korea FDA) ;
  • Kim, Soon-Sun (National Institute of Toxicological Research, Korea FDA) ;
  • Sohn, Kyung-Hee (National Institute of Toxicological Research, Korea FDA) ;
  • Kwack, Seung-Jun (National Institute of Toxicological Research, Korea FDA) ;
  • Lee, Rhee-Da (National Institute of Toxicological Research, Korea FDA) ;
  • Chae, Soo-Yeong (National Institute of Toxicological Research, Korea FDA) ;
  • An, Sang-Mi (National Institute of Toxicological Research, Korea FDA) ;
  • Hur, Man-Wook (Dep. of Biochem. and Mol.Biol., Yonsei Univ. College of Medicine)
  • Published : 2002.11.01
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Abstract

Alcohol drinking during pregnancy can result in abnormal fetal development including fetal alcohol syndrome (FAS). The molecular mechanisms of FAS, however, is not completely elucidated. In the present study, we evaluated the developmental toxicity of ethanol and its metabolite, acetaldehyde using post implantation whole embryo culture and determined changes of gene expression by ethanol treatment by cDNA microarray.(omitted)

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