Proceedings of the KACD Conference (대한치과보존학회:학술대회논문집)

The Korean Academy of Conservative Dentistry (대한치과보존학회)
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Influence of NK1 receptor antagonists applied iontophoretically on pulpal blood flow in the cat

  • Kim, Young-Kyung (Department of Conservative Dentistry, School of Dentistry, Kyungpook National University) ;
  • Park, Jeong-Won (Department of Conservative Dentistry, School of Dentistry, Kyungpook National University) ;
  • Kim, Sung-Kyo (Department of Conservative Dentistry, School of Dentistry, Kyungpook National University)
  • Published : 2003.11.01
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Abstract

Pulpal inflammation is a kind of neurogenic inflammation and it shows vascular changes such as vasodilation and changes in vascular leakage. Various kinds of neuropeptides including substance P (SP) are known to be involved in the pulpal inflammation. The purpose of this study was to investigate the influence of NK1 receptor antagonists on the pulpal blood flow (PBF) when applied iontophoretically through the dentinal cavity of the teeth in order to understand whether iontophoretic ally applied NK1 receptor antagonists can control the pulpal inflammation.(omitted)

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