한국동물번식학회:학술대회논문집 (Proceedings of the KSAR Conference)
- 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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- Pages.31-31
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- 2003
Effects of Maternal Exposure to Xenoestrogens on the Steroidogenesis in Mouse Testis of Male Offspring
- An, Su-Yeon (Animal Resource Research Center, Konkuk University, Department of Physiology, Eulji University School of Medicine) ;
- Lee, Hoon-Taek (Animal Resource Research Center, Konkuk University) ;
- Kim, Suel-Kee (Department of Lie Science, Hanyang University) ;
- Yoon, Yong-Dal (Department of Lie Science, Hanyang University) ;
- Lee, Ho-Joon (Department of Physiology, Eulji University School of Medicine)
- 발행 : 2003.06.01
초록
The incidence of reproductive abnormalities in the male has been reported to have increased during the past 50 years. These changes may be attributable to the presence of chemical with oestrogenic activity in our environment. Present study was carried out to determine the effects of maternal exposure to xenoestrogens on the testicular development and on the transcriptional expression of the steroidogenic enzyme and subunits of inhibin/activin in testis of male offspring. Pregnant female mice were administrated with 4-tert-octylphenol (OP; 2, 20, 200mg/kg), Bisphenol A (BPA; 2, 20, 200