Disseminated Juvenile Pilocytic Astrocytoma in Childhood

  • Kima, JI-Hye (Department of Radiology, Division of Hematology/Oncology Children's Hospital and Medical Center, University of Washington School of Medicine, Seattle, Washington) ;
  • Dennis WW Shaw (Department of Radiology, Division of Hematology/Oncology Children's Hospital and Medical Center, University of Washington School of Medicine, Seattle, Washington) ;
  • Richard Ellenbogen (Department of Neurosurgery, and Division of Hematology/Oncology Children′s Hospital and Medical Center, University of Washington School of Medicine, Seattle, Washington) ;
  • Geyer J Russel (Department of Pediatrics, Division of Hematology/Oncology Children's Hospital and Medical Center, University of Washington School of Medicine, Seattle, Washington.)
  • Published : 2003.10.01

Abstract

To evaluate the clinical characteristics and outcome of the patients with disseminated pilocytic astrocytoma compared to non-disseminated disease and to discuss treatment options for disseminated disease. We Identified patients with disseminated pilocytic astrocytoma from our Tumor Registry over 21 years of period and reviewed medical records and neuroimages to determine location of the tumor, pattern of dissemination, clinical characteristics, treatment, and outcome. 24 controls without dissemination, matched for age at diagnosis, tumor histology, and primary location were selected from the same registry and case/control comparison was done using Kaplan-Meier survival analysis.

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