대한화장품학회:학술대회논문집 (Proceedings of the SCSK Conference)
- 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
- /
- Pages.313-319
- /
- 2003
LIPID-SOLUBLE VC DERIVATIVE ASCORBIC ACID TETRA-2-HEXYLDECANOATE (VC-IP) AS AN ANTI-AGING AGENT
- Obayashi, K. (Nikko Chemicals Group, Cosmos Technical Center Co., Ltd.) ;
- Ochiai, Y. (Nikko Chemicals Group, Cosmos Technical Center Co., Ltd) ;
- Ochiai, Y. (Nikko Chemicals Group, Cosmos Technical Center Co., Ltd) ;
- Masaki, H. (Nikko Chemicals Group, Cosmos Technical Center Co., Ltd) ;
- Kurata, Y. (Nikko Chemicals Group, Cosmos Technical Center Co., Ltd.)
- 발행 : 2003.09.01
초록
It is well known that ascorbic acid (VC) is an important factor for several physiological reactions. In the skin, VC works as an anti-aging agent due to removing of oxidative stress generated by UV irradiation and stimulation of collagen synthesis. Thus, developing more effective VC derivatives is an important issue in creating anti-aging skin care products. Our study succeeded to develop a novel ascorbic acid derivative, ascorbic acid tetra-2-hexyldecanoate (VC-IP), which is a lipid-soluble pro-VC. The purpose of this study was to indicate the effects of VC-IP as pro-VC and anti-aging agent. First, it was examined whether VC-IP is converted to VC in physiological conditions. Since VC was detected from the cell extracts treated with VC-IP, it was indicated that VC-IP is a pro- VC.(omiited)