대한화장품학회:학술대회논문집 (Proceedings of the SCSK Conference)
- 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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- Pages.660-671
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- 2003
Inhibitors of Melanogenesis from the Roots of Peucedanum praeruptorum
- Kim, Cheong-Taek (C.I. Center, LG Household & Health Care) ;
- Kim, Won-Chan (C.I. Center, LG Household & Health Car) ;
- Jin, Mu-Hyun (C.I. Center, LG Household & Health Car) ;
- Kim, Ho-Jeong (C.I. Center, LG Household & Health Car) ;
- Kang, Sang-Jin (C.I. Center, LG Household & Health Car) ;
- Cho, Wan-Goo (C.I. Center, LG Household & Health Care)
- 발행 : 2003.09.01
초록
A chemical investigation of Peucedanum praeruptorum has resulted in the isolation of 3 khellactone derivatives, which have inhibitory effects on melanogenesis in B16 mouse melanoma cell lines. The khellactone derivatives were isolated from the crude extract of the roots of Pecedanum praeruptorum by a combination of adsorption chromatography and HPLC. The structures of isolated compounds were identified as 3', 4'-diangeloyl-cis-khellactone, 3'-angeloyl-4'-senecioyl-cis-khellactone and, 3', 4'-disenecioyl-cis-khellactone by
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