Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)
- 2003.09b
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- Pages.268-279
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- 2003
Nano Capsulization of Ceramide and the Efficacy of Atopy Skin
- Zhoh, Choon-Koo (Dept. of Chemical and Environmental Engineering, Soongsil University) ;
- Han, Chang-Giu (Cosmetics Research Institute, Dong-A Pharm. Co., LTD) ;
- Hong, Se-Heum (Dept. of Chemical and Environmental Engineering, Soongsil University) ;
- Kim, In-Young (Skin Science Research Institute,R & D Center, Enprani Co., LTD) ;
- Lee, Hee-Seob (Dept. of Chemical and Environmental Engineering, Soongsil University)
- Published : 2003.09.01
Abstract
The nano capsulation of the ceramide was a technique that capsulated ceramide III and tocopheryl linoleate at the mono-vesicle, so as to act the horny layer in skin. It was used 0.5-5.0 wt% of hydrogenated lecithin and 0.01~2.00 wt% of lysolecithin as the membrane-strengthen agents of the mono-vesicle, 5.0~10 wt% of propylene glycol and 5.0~10.0 wt% of ethyl alcohol made by high-pressure Microfluidizer. To enhance the moisturizing efficacy and treat an atopy skin, used ceramide III and tocopheryl linoleate as the active ingredients, and it was made the nano-capsule that synthetic emulsifiers were free. The optimal condition of capsulation of nano ceramide was as follows. The conditions were 3 times at 1,000bar and 60-7