Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.115-115
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- 2003
In vitro cytotoxicity of Chloromethyl-2-dihydroxyphosphinyl-6, 7-dimethoxy-l,2,3,4-tetra hydroisoquinoline on HL60 cells and apoptotic effet
- Kim, Kun-Jung (Department of Pathology, College of Oriental Medicine, Wonkwang University) ;
- Ju, Sung-Min (Department of Pathology, College of Oriental Medicine, Wonkwang University) ;
- Yeom, Kee-Bok (Department of Pathology, College of Oriental Medicine, Wonkwang University) ;
- Kim, Dae-Geun (Department of Pathology, College of Oriental Medicine, Wonkwang University) ;
- Lee, Chai-Ho (Division of Natural Science and Technology, College of Natural Sciences, Wonkwang University) ;
- Kim, Won-Sin (Division of Natural Science and Technology, College of Natural Sciences, Wonkwang University) ;
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Han, Dong-Min
(Division of Natural Science and Technology, College of Natural Sciences, Wonkwang University)
;
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Jeon, Byung-Hun
(Department of Pathology, College of Oriental Medicine, Wonkwang University)
- Published : 2003.10.01
Abstract
The chloromethyl-2-dihydroxyphosphinyl-6, 7-dimethoxy-1,2,3,4-tetrahydro isoquino- line (CDDT) is a newly synthesized agent which is derivated from 1,2,3,4- Tetrahydroiso- quinoline (TIQ). The TIQs include potent cytotoxic agents that display a range of antitumor activities, antimicrobial activity, and other biological properties. (omitted)