Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.120-120
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- 2003
Inhibition by Hyaluronan of Collagen-Induced Activation of Hepatic Stellate Cells
- Lee, Gum-Hwa (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
- Cho, Min-Kyung (College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University) ;
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Kim, Sang-Geon
(College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University)
- Published : 2003.10.01
Abstract
Synthesis and distribution of extracellular matrix (ECM) components are dynamically altered in response to the pathophysiological processes including infection, inflammation and apoptosis. In particular, the levels of hyaluronan (HA) change with concomitant increases in the levels of collagen (e.g. type I collagen) and fibronectin in chronic liver diseases.(omitted)