Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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PC12 and Cortical Neuron cell Death by Bisphenol A Through ERK Signal Pathway: Role of Estrogen-Receptor $\beta$

  • Lee, Yoot-Mo (Department of Pharmacology, Chungbuk University) ;
  • Seong, Min-Je (Department of Pharmacology, Chungbuk University) ;
  • Lee, Sun-Young (Department of Pharmacology, Chungbuk University) ;
  • Lee, Sang-Min (Department of Pharmacology, Chungbuk University) ;
  • Kim, Tae-Seong (Department of Pharmacology, Chungbuk University) ;
  • Han, Soon-Young (Department of Pharmacology, Chungbuk University) ;
  • Yoo, Han-Soo (Department of Pharmacology, Chungbuk University) ;
  • Lee, Myung-Koo (Department of Pharmacology, Chungbuk University) ;
  • Oh, Ki-Wan (Department of Pharmacology, Chungbuk University)
  • Published : 2003.10.01
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Abstract

Bisphenol A (BPA) mimics estrogen and its activity is one third to one quarter that of estradiol. BPA, an ubiquitous environmental contaminent has been shown to cause development reproductive toxicity and carcinogenic effect. BPA may do physiological action through ER${\alpha}$ and ER${\beta}$ which are expressed in central nerve system.(omitted)

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